Growth Metrics

BeOne Medicines (ONC) Gross Margin (2017 - 2026)

BeOne Medicines (ONC) reported Gross Margin of 88.95% for Q1 2026, up 372.0% year-over-year from 18.85% in Q1 2025, and down 1.7% on a QoQ basis from 90.49% in Q4 2025.

BeOne Medicines (ONC) has 10 years of Gross Margin data on file, last reported at 88.95% in Q1 2026.

  • Quarterly Gross Margin rose 372.0% year-over-year to 88.95% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 88.31% (up 350.0% YoY) and the FY2025 annual result came in at 87.49%, up 308.0% from the prior year.
  • Gross Margin declined to 88.95% in Q1 2026 per ONC's latest filing, from 90.49% in the prior quarter.
  • Across five years, Gross Margin topped out at 90.49% in Q4 2025 and bottomed at 78.72% in Q1 2022.
  • The 5-year median for Gross Margin is 83.87% (2023), against an average of 84.17%.
  • The widest annual swing landed in 2022, when Gross Margin plunged 1588 bps; it then jumped 742 bps in 2023.
  • Tracing ONC's Gross Margin over 5 years: stood at 80.66% in 2022, then advanced by 3 bps to 83.32% in 2023, then increased by 3 bps to 85.76% in 2024, then advanced by 6 bps to 90.49% in 2025, then dropped by 2 bps to 88.95% in 2026.
  • Per Business Quant, the three latest ONC Gross Margin figures stand at 88.95% (Q1 2026), 90.49% (Q4 2025), and 86.09% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 79.04%
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 86.85%
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 91.79%
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 82.22%
10 BeOne Medicines - - 1.35 Bn 88.95%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 88.95%
Dec 31, 2025 90.49%
Sep 30, 2025 86.09%
Jun 30, 2025 87.49%
Mar 31, 2025 85.23%
Dec 31, 2024 85.76%
Sep 30, 2024 82.98%
Jun 30, 2024 85.13%
Mar 31, 2024 83.38%
Dec 31, 2023 83.32%
Sep 30, 2023 87.67%
Jun 30, 2023 83.87%
Mar 31, 2023 81.74%
Dec 31, 2022 80.66%
Sep 30, 2022 80.25%
Jun 30, 2022 79.16%
Mar 31, 2022 78.72%
Dec 31, 2021 77.31%
Sep 30, 2021 77.03%
Jun 30, 2021 75.82%
Mar 31, 2021 94.61%
Dec 31, 2020 78.94%
Sep 30, 2020 76.81%
Jun 30, 2020 78.20%
Mar 31, 2020 72.82%
Dec 31, 2019 68.39%
Sep 30, 2019 59.90%
Jun 30, 2019 88.11%
Mar 31, 2019 80.39%
Dec 31, 2018 84.33%
Sep 30, 2018 83.94%
Jun 30, 2018 88.15%
Mar 31, 2018 86.02%
Dec 31, 2017 83.33%
Sep 30, 2017 99.12%