Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Gross Margin came in at 86.85% in Q1 2026, down 5.0% year-on-year from 91.42% in Q1 2025, and up 1.71% quarter-over-quarter from 85.39% in Q4 2025.

Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Gross Margin history runs 18 years deep, the most recent figure standing at 86.85% for Q1 2026.

  • On a quarterly basis, Gross Margin fell 5.0% year-over-year to 86.85% in Q1 2026; TTM through Mar 2026 was 86.24%, a 21.0% increase from a year earlier, with the FY2025 full-year figure at 86.24%, up 13.0% from the prior year.
  • Gross Margin advanced to 86.85% in Q1 2026 per VRTX's latest filing, from 85.39% in the prior quarter.
  • Across five years, Gross Margin topped out at 88.76% in Q1 2023 and bottomed at 85.38% in Q4 2023.
  • The 5-year median for Gross Margin is 86.9% (2025), against an average of 86.88%.
  • Across the five-year window, Gross Margin soared 79 bps in 2022 and tumbled 231 bps in 2023, its largest moves.
  • Year by year, Gross Margin stood at 87.7% in 2022, then retreated by 3 bps to 85.38% in 2023, then increased by 0 bps to 85.46% in 2024, then declined by 0 bps to 85.39% in 2025, then rose by 2 bps to 86.85% in 2026.
  • Per Business Quant, the three latest VRTX Gross Margin figures stand at 86.85% (Q1 2026), 85.39% (Q4 2025), and 86.52% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 88.95%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 91.79%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 90.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn 82.22%

Historic Data

Download Data
DateValue
Mar 31, 2026 86.85%
Dec 31, 2025 85.39%
Sep 30, 2025 86.52%
Jun 30, 2025 86.25%
Mar 31, 2025 86.90%
Dec 31, 2024 85.46%
Sep 30, 2024 85.84%
Jun 30, 2024 85.94%
Mar 31, 2024 87.27%
Dec 31, 2023 85.38%
Sep 30, 2023 87.17%
Jun 30, 2023 87.62%
Mar 31, 2023 88.76%
Dec 31, 2022 87.70%
Sep 30, 2022 87.60%
Jun 30, 2022 88.08%
Mar 31, 2022 88.28%
Dec 31, 2021 88.06%
Sep 30, 2021 88.08%
Jun 30, 2021 87.29%