Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026)
Vertex Pharmaceuticals (VRTX) posted quarterly Gross Margin of 86.85% for Q1 2026, down 5.0% year-over-year from 91.42% in Q1 2025, and up 1.71% quarter-over-quarter from 85.39% in Q4 2025.
Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Gross Margin history runs 18 years deep, the most recent figure standing at 86.85% for Q1 2026.
- In Q1 2026, Gross Margin fell 5.0% year-over-year to 86.85%; the TTM figure through Mar 2026 stood at 86.24% (up 21.0% YoY), while the FY2025 annual figure was 86.24%, up 13.0% from the prior year.
- Gross Margin for Q1 2026 stood at 86.85%, up from 85.39% in the prior quarter.
- The five-year high for Gross Margin was 88.76% in Q1 2023, with the low at 85.38% in Q4 2023.
- The 5-year median for Gross Margin is 86.9% (2025), against an average of 86.88%.
- The sharpest annual moves came in 2022 and 2023: Gross Margin soared 79 bps in 2022, then slumped 231 bps in 2023.
- Vertex Pharmaceuticals' Gross Margin stood at 87.7% in 2022, then fell by 3 bps to 85.38% in 2023, then grew by 0 bps to 85.46% in 2024, then dropped by 0 bps to 85.39% in 2025, then increased by 2 bps to 86.85% in 2026.
- Business Quant data shows VRTX's Gross Margin at 86.85% in Q1 2026, 85.39% in Q4 2025, and 86.52% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 90.68% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 89.76% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 60,631,834.75% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | - |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 76.90% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 84.20% |
| 10 | Roivant Sciences | 26.16 Bn | 26.85 Bn | 1.16 Mn | 80.31% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 85.33% |
| Mar 31, 2026 | 86.85% |
| Dec 31, 2025 | 85.39% |
| Sep 30, 2025 | 86.52% |
| Jun 30, 2025 | 86.25% |
| Mar 31, 2025 | 86.90% |
| Dec 31, 2024 | 85.46% |
| Sep 30, 2024 | 85.84% |
| Jun 30, 2024 | 85.94% |
| Mar 31, 2024 | 87.27% |
| Dec 31, 2023 | 85.38% |
| Sep 30, 2023 | 87.17% |
| Jun 30, 2023 | 87.62% |
| Mar 31, 2023 | 88.76% |
| Dec 31, 2022 | 87.70% |
| Sep 30, 2022 | 87.60% |
| Jun 30, 2022 | 88.08% |
| Mar 31, 2022 | 88.28% |
| Dec 31, 2021 | 88.06% |
| Sep 30, 2021 | 88.08% |