Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026)
Vertex Pharmaceuticals (VRTX) posted quarterly Gross Margin of 86.85% for Q1 2026, down 5.0% year-over-year from 91.42% in Q1 2025, and up 1.71% quarter-over-quarter from 85.39% in Q4 2025.
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Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Gross Margin history runs 18 years deep, the most recent figure standing at 86.85% for Q1 2026.
- In Q1 2026, Gross Margin fell 5.0% year-over-year to 86.85%; the TTM figure through Mar 2026 stood at 86.24% (up 21.0% YoY), while the FY2025 annual figure was 86.24%, up 13.0% from the prior year.
- Gross Margin for Q1 2026 stood at 86.85%, up from 85.39% in the prior quarter.
- The five-year high for Gross Margin was 88.76% in Q1 2023, with the low at 85.38% in Q4 2023.
- The 5-year median for Gross Margin is 86.9% (2025), against an average of 86.88%.
- The sharpest annual moves came in 2022 and 2023: Gross Margin soared 79 bps in 2022, then slumped 231 bps in 2023.
- Vertex Pharmaceuticals' Gross Margin stood at 87.7% in 2022, then fell by 3 bps to 85.38% in 2023, then grew by 0 bps to 85.46% in 2024, then dropped by 0 bps to 85.39% in 2025, then increased by 2 bps to 86.85% in 2026.
- Business Quant data shows VRTX's Gross Margin at 86.85% in Q1 2026, 85.39% in Q4 2025, and 86.52% in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.76 Bn | 131.91 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 85.72 Bn | 77.72 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 63.56 Bn | 58.38 Bn | 1.37 Bn | 90.43% |
| 4 | Moderna | 57.87 Bn | 52.73 Bn | 52.00 Mn | 35.86% |
| 5 | Revolution Medicines | 44.06 Bn | 44.06 Bn | - | - |
| 6 | BeOne Medicines | 40.08 Bn | 34.98 Bn | 1.53 Bn | 89.76% |
| 7 | Alnylam Pharmaceuticals | 35.50 Bn | 32.20 Bn | 992.69 Mn | 76.90% |
| 8 | Royalty Pharma | 28.54 Bn | 27.70 Bn | - | - |
| 9 | Insmed | 27.49 Bn | 26.33 Bn | 358.27 Mn | 84.20% |
| 10 | Incyte | 25.59 Bn | 21.06 Bn | 1.57 Bn | 93.73% |
Historic Data
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Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 85.33% |
| Mar 31, 2026 | 86.85% |
| Dec 31, 2025 | 85.39% |
| Sep 30, 2025 | 86.52% |
| Jun 30, 2025 | 86.25% |
| Mar 31, 2025 | 86.90% |
| Dec 31, 2024 | 85.46% |
| Sep 30, 2024 | 85.84% |
| Jun 30, 2024 | 85.94% |
| Mar 31, 2024 | 87.27% |
| Dec 31, 2023 | 85.38% |
| Sep 30, 2023 | 87.17% |
| Jun 30, 2023 | 87.62% |
| Mar 31, 2023 | 88.76% |
| Dec 31, 2022 | 87.70% |
| Sep 30, 2022 | 87.60% |
| Jun 30, 2022 | 88.08% |
| Mar 31, 2022 | 88.28% |
| Dec 31, 2021 | 88.06% |
| Sep 30, 2021 | 88.08% |