Vertex Pharmaceuticals (VRTX) Gross Margin (2010 - 2026)
Vertex Pharmaceuticals (VRTX) recorded quarterly Gross Margin of 86.85% in Q1 2026, up 1.71% quarter-over-quarter from 85.39% in Q4 2025, and down 5.0% on a YoY basis from 91.42% in Q1 2025.
Vertex Pharmaceuticals (VRTX) Gross Margin (2010 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Gross Margin history runs 17 years deep, the most recent figure standing at 86.85% for Q1 2026.
- In Q1 2026, Gross Margin fell 5.0% year-over-year to 86.85%; the TTM figure through Mar 2026 stood at 86.24% (up 21.0% YoY), while the FY2025 annual figure was 86.24%, up 13.0% from the prior year.
- Gross Margin was 86.85% for Q1 2026 at Vertex Pharmaceuticals, up from 85.39% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 88.76% in Q1 2023 to a low of 85.38% in Q4 2023.
- Historically, Gross Margin has averaged 86.88% across 5 years, with a median of 86.9% in 2025.
- The sharpest annual moves came in 2022 and 2023: Gross Margin jumped 79 bps in 2022, then tumbled 231 bps in 2023.
- A 5-year view of Gross Margin shows it stood at 87.7% in 2022, then retreated by 3 bps to 85.38% in 2023, then increased by 0 bps to 85.46% in 2024, then declined by 0 bps to 85.39% in 2025, then rose by 2 bps to 86.85% in 2026.
- The last three Gross Margin figures came in at 86.85% (Q1 2026), 85.39% (Q4 2025), and 86.52% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Regeneron Pharmaceuticals | 63.43 Bn | 54.67 Bn | 3.31 Bn | 91.79% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 86.85% |
| Dec 31, 2025 | 85.39% |
| Sep 30, 2025 | 86.52% |
| Jun 30, 2025 | 86.25% |
| Mar 31, 2025 | 86.90% |
| Dec 31, 2024 | 85.46% |
| Sep 30, 2024 | 85.84% |
| Jun 30, 2024 | 85.94% |
| Mar 31, 2024 | 87.27% |
| Dec 31, 2023 | 85.38% |
| Sep 30, 2023 | 87.17% |
| Jun 30, 2023 | 87.62% |
| Mar 31, 2023 | 88.76% |
| Dec 31, 2022 | 87.70% |
| Sep 30, 2022 | 87.60% |
| Jun 30, 2022 | 88.08% |
| Mar 31, 2022 | 88.28% |
| Dec 31, 2021 | 88.06% |
| Sep 30, 2021 | 88.08% |
| Jun 30, 2021 | 87.29% |