Growth Metrics

Vertex Pharmaceuticals (VRTX) Gross Margin (2010 - 2026)

Vertex Pharmaceuticals' quarterly Gross Margin came in at 86.85% in Q1 2026, down 5.0% year-on-year from 91.42% in Q1 2025, and up 1.71% quarter-over-quarter from 85.39% in Q4 2025.

Vertex Pharmaceuticals has reported Gross Margin for 17 years, with the latest figure at 86.85% in Q1 2026.

  • For the quarter ending Q1 2026, Gross Margin fell 5.0% year-over-year to 86.85%; the trailing twelve-month figure through Mar 2026 stood at 86.24% (up 21.0% YoY), and the FY2025 full-year result was 86.24%, up 13.0% from the prior year.
  • Gross Margin for Q1 2026 stood at 86.85%, up from 85.39% in the prior quarter.
  • The five-year high for Gross Margin was 88.76% in Q1 2023, with the low at 85.38% in Q4 2023.
  • Average Gross Margin over 5 years is 86.88%, with a median of 86.9% recorded in 2025.
  • Year-over-year, Gross Margin soared 79 bps in 2022 and tumbled 231 bps in 2023.
  • Tracing VRTX's Gross Margin over 5 years: stood at 87.7% in 2022, then decreased by 3 bps to 85.38% in 2023, then rose by 0 bps to 85.46% in 2024, then fell by 0 bps to 85.39% in 2025, then gained by 2 bps to 86.85% in 2026.
  • The last three Gross Margin figures came in at 86.85% (Q1 2026), 85.39% (Q4 2025), and 86.52% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 79.04%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 86.85%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 91.79%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 82.22%
10 Revolution Medicines 31.20 Bn 31.20 Bn - -

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 86.85%
Dec 31, 2025 85.39%
Sep 30, 2025 86.52%
Jun 30, 2025 86.25%
Mar 31, 2025 86.90%
Dec 31, 2024 85.46%
Sep 30, 2024 85.84%
Jun 30, 2024 85.94%
Mar 31, 2024 87.27%
Dec 31, 2023 85.38%
Sep 30, 2023 87.17%
Jun 30, 2023 87.62%
Mar 31, 2023 88.76%
Dec 31, 2022 87.70%
Sep 30, 2022 87.60%
Jun 30, 2022 88.08%
Mar 31, 2022 88.28%
Dec 31, 2021 88.06%
Sep 30, 2021 88.08%
Jun 30, 2021 87.29%
Mar 31, 2021 88.85%
Dec 31, 2020 87.52%
Sep 30, 2020 87.90%
Jun 30, 2020 87.90%
Mar 31, 2020 89.27%
Dec 31, 2019 -18.75%
Sep 30, 2019 86.11%
Jun 30, 2019 85.58%
Mar 31, 2019 88.92%
Dec 31, 2018 85.95%
Sep 30, 2018 85.82%
Jun 30, 2018 86.12%
Mar 31, 2018 88.82%
Dec 31, 2017 87.10%
Sep 30, 2017 87.40%
Jun 30, 2017 86.91%
Mar 31, 2017 93.43%
Dec 31, 2016 87.00%
Sep 30, 2016 87.01%
Jun 30, 2016 89.63%
Mar 31, 2016 87.49%
Dec 31, 2015 84.73%
Sep 30, 2015 89.99%
Jun 30, 2015 90.72%
Mar 31, 2015 92.83%
Dec 31, 2014 92.19%
Sep 30, 2014 92.55%
Jun 30, 2014 92.11%
Mar 31, 2014 92.76%
Dec 31, 2013 89.69%
Sep 30, 2013 90.96%
Jun 30, 2013 90.31%
Mar 31, 2013 90.57%
Dec 31, 2012 77.37%
Sep 30, 2012 90.87%
Jun 30, 2012 75.01%
Mar 31, 2012 93.10%
Dec 31, 2011 95.93%
Sep 30, 2011 91.59%
Mar 31, 2011 100.00%
Jun 30, 2010 100.00%