Vertex Pharmaceuticals (VRTX) Gross Margin (2010 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Gross Margin of 86.85% in Q1 2026, up 1.71% quarter-over-quarter from 85.39% in Q4 2025, and down 5.0% on a YoY basis from 91.42% in Q1 2025.

Vertex Pharmaceuticals (VRTX) Gross Margin (2010 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Gross Margin history runs 17 years deep, the most recent figure standing at 86.85% for Q1 2026.

  • In Q1 2026, Gross Margin fell 5.0% year-over-year to 86.85%; the TTM figure through Mar 2026 stood at 86.24% (up 21.0% YoY), while the FY2025 annual figure was 86.24%, up 13.0% from the prior year.
  • Gross Margin was 86.85% for Q1 2026 at Vertex Pharmaceuticals, up from 85.39% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 88.76% in Q1 2023 to a low of 85.38% in Q4 2023.
  • Historically, Gross Margin has averaged 86.88% across 5 years, with a median of 86.9% in 2025.
  • The sharpest annual moves came in 2022 and 2023: Gross Margin jumped 79 bps in 2022, then tumbled 231 bps in 2023.
  • A 5-year view of Gross Margin shows it stood at 87.7% in 2022, then retreated by 3 bps to 85.38% in 2023, then increased by 0 bps to 85.46% in 2024, then declined by 0 bps to 85.39% in 2025, then rose by 2 bps to 86.85% in 2026.
  • The last three Gross Margin figures came in at 86.85% (Q1 2026), 85.39% (Q4 2025), and 86.52% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn 91.79%

Historic Data

Download Data
DateValue
Mar 31, 2026 86.85%
Dec 31, 2025 85.39%
Sep 30, 2025 86.52%
Jun 30, 2025 86.25%
Mar 31, 2025 86.90%
Dec 31, 2024 85.46%
Sep 30, 2024 85.84%
Jun 30, 2024 85.94%
Mar 31, 2024 87.27%
Dec 31, 2023 85.38%
Sep 30, 2023 87.17%
Jun 30, 2023 87.62%
Mar 31, 2023 88.76%
Dec 31, 2022 87.70%
Sep 30, 2022 87.60%
Jun 30, 2022 88.08%
Mar 31, 2022 88.28%
Dec 31, 2021 88.06%
Sep 30, 2021 88.08%
Jun 30, 2021 87.29%