Vertex Pharmaceuticals (VRTX) Gross Margin (2010 - 2026)
Vertex Pharmaceuticals' Gross Margin was 85.33% in Q2 2026, down 0.93 percentage points from 86.25% a year earlier and down 1.52 percentage points from the prior quarter.
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Analysis
Vertex Pharmaceuticals (VRTX) Gross Margin (2010 - 2026) Analysis & Trends
On a trailing twelve-month basis, Vertex Pharmaceuticals' Gross Margin was 86.00% through Jun 30, 2026, down 0.11 percentage points year-over-year; for FY2025, it came in at 86.24%, up 0.13 percentage points from FY2024.
- Gross Margin shows a five-year change of -1.89 percentage points (FY2020 to FY2025).
- In earlier years, Gross Margin was 86.11% in FY2024 (-1.10 pp), 87.21% in FY2023 (-0.69 pp), 87.90% in FY2022 (-0.16 pp) and 88.06% in FY2021 (-0.07 pp).
- The Q2 2026 figure marks the lowest quarterly Gross Margin since Q4 2015.
- Compared with a year earlier, Gross Margin has declined for three straight quarters, with an average year-over-year change of -0.21 percentage points over the last eight quarters.
- The best year-over-year quarter for Gross Margin over five years was Q2 2022 (a gain of 0.79 percentage points); the worst was Q4 2023 (a drop of 2.31 percentage points).
- Per Business Quant data, VRTX's Gross Margin in the three quarters before Q2 2026 was 86.85% (Q1 2026), 85.39% (Q4 2025) and 86.52% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,221.09 Bn | 1,194.71 Bn | 20.46 Bn | 83.88% |
| 2 | Johnson & Johnson | 656.38 Bn | 576.24 Bn | 17.30 Bn | 68.12% |
| 3 | AbbVie | 510.79 Bn | 478.80 Bn | 13.12 Bn | 75.38% |
| 4 | Merck | 363.00 Bn | 317.38 Bn | 12.21 Bn | 73.54% |
| 5 | Novartis Ag | 313.89 Bn | 287.12 Bn | - | - |
| 6 | Astrazeneca | 290.02 Bn | 263.91 Bn | 13.26 Bn | 88.03% |
| 7 | Amgen | 249.59 Bn | 204.98 Bn | 7.24 Bn | 72.04% |
| 8 | Gilead Sciences | 208.15 Bn | 183.26 Bn | 6.73 Bn | 81.07% |
| 9 | Pfizer | 170.74 Bn | 118.10 Bn | 12.56 Bn | 75.71% |
| 10 | Vertex Pharmaceuticals | 137.20 Bn | 109.19 Bn | 2.91 Bn | 84.71% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 84.71% |
| Jun 30, 2026 | 85.33% |
| Mar 31, 2026 | 86.85% |
| Dec 31, 2025 | 85.39% |
| Sep 30, 2025 | 86.52% |
| Jun 30, 2025 | 86.25% |
| Mar 31, 2025 | 86.90% |
| Dec 31, 2024 | 85.46% |
| Sep 30, 2024 | 85.84% |
| Jun 30, 2024 | 85.94% |
| Mar 31, 2024 | 87.27% |
| Dec 31, 2023 | 85.38% |
| Sep 30, 2023 | 87.17% |
| Jun 30, 2023 | 87.62% |
| Mar 31, 2023 | 88.76% |
| Dec 31, 2022 | 87.70% |
| Sep 30, 2022 | 87.60% |
| Jun 30, 2022 | 88.08% |
| Mar 31, 2022 | 88.28% |
| Dec 31, 2021 | 88.06% |
API Access
Vertex Pharmaceuticals Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "VRTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();