Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026)
Vertex Pharmaceuticals (VRTX) posted Gross Margin of 85.33% for Q2 2026, down 1.75% on a QoQ basis from 86.85% in Q1 2026, and down 93.0% year-over-year from 1218.95% in Q2 2025.
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Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals has reported Gross Margin for 18 years, with the latest figure at 85.33% in Q2 2026.
- On a quarterly basis, Gross Margin fell 93.0% year-over-year to 85.33% in Q2 2026; TTM through Jun 2026 was 86.0%, a 11.0% decrease from a year earlier, with the FY2025 full-year figure at 86.24%, up 13.0% from the prior year.
- Gross Margin was 85.33% for Q2 2026 at Vertex Pharmaceuticals, down from 86.85% in the prior quarter.
- The five-year high for Gross Margin was 88.76% in Q1 2023, with the low at 85.33% in Q2 2026.
- Average Gross Margin over 5 years is 86.8%, with a median of 86.87% recorded in 2025.
- The sharpest annual moves came in 2022 and 2023: Gross Margin surged 79 bps in 2022, then slumped 231 bps in 2023.
- Over 5 years, Gross Margin stood at 87.7% in 2022, then decreased by 3 bps to 85.38% in 2023, then rose by 0 bps to 85.46% in 2024, then fell by 0 bps to 85.39% in 2025, then slipped by 0 bps to 85.33% in 2026.
- The last three Gross Margin figures came in at 85.33% (Q2 2026), 86.85% (Q1 2026), and 85.39% (Q4 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 649.01 Bn | 628.25 Bn | 17.26 Bn | 68.19% |
| 2 | AbbVie | 468.55 Bn | 462.03 Bn | 12.70 Bn | 74.74% |
| 3 | Merck | 365.49 Bn | 358.40 Bn | 12.21 Bn | 73.54% |
| 4 | Novartis Ag | 272.39 Bn | 265.10 Bn | 11.24 Bn | 78.02% |
| 5 | Astrazeneca | 253.18 Bn | 247.96 Bn | 12.86 Bn | 83.60% |
| 6 | Amgen | 219.53 Bn | 205.54 Bn | 7.24 Bn | 72.04% |
| 7 | Gilead Sciences | 187.85 Bn | 184.59 Bn | 6.22 Bn | 79.76% |
| 8 | Pfizer | 160.56 Bn | 149.16 Bn | 10.94 Bn | 72.78% |
| 9 | Vertex Pharmaceuticals | 130.81 Bn | 122.96 Bn | 2.84 Bn | 85.33% |
| 10 | Bristol Myers Squibb | 124.95 Bn | 113.89 Bn | 9.25 Bn | 71.28% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 85.33% |
| Mar 31, 2026 | 86.85% |
| Dec 31, 2025 | 85.39% |
| Sep 30, 2025 | 86.52% |
| Jun 30, 2025 | 86.25% |
| Mar 31, 2025 | 86.90% |
| Dec 31, 2024 | 85.46% |
| Sep 30, 2024 | 85.84% |
| Jun 30, 2024 | 85.94% |
| Mar 31, 2024 | 87.27% |
| Dec 31, 2023 | 85.38% |
| Sep 30, 2023 | 87.17% |
| Jun 30, 2023 | 87.62% |
| Mar 31, 2023 | 88.76% |
| Dec 31, 2022 | 87.70% |
| Sep 30, 2022 | 87.60% |
| Jun 30, 2022 | 88.08% |
| Mar 31, 2022 | 88.28% |
| Dec 31, 2021 | 88.06% |
| Sep 30, 2021 | 88.08% |
API Access
Vertex Pharmaceuticals Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "VRTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();