Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026)
Vertex Pharmaceuticals' (VRTX) quarterly Gross Margin came in at 86.85% in Q1 2026, down 5.0% year-on-year from 91.42% in Q1 2025, and up 1.71% quarter-over-quarter from 85.39% in Q4 2025.
Vertex Pharmaceuticals (VRTX) Gross Margin (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Gross Margin history runs 18 years deep, the most recent figure standing at 86.85% for Q1 2026.
- On a quarterly basis, Gross Margin fell 5.0% year-over-year to 86.85% in Q1 2026; TTM through Mar 2026 was 86.24%, a 21.0% increase from a year earlier, with the FY2025 full-year figure at 86.24%, up 13.0% from the prior year.
- Gross Margin advanced to 86.85% in Q1 2026 per VRTX's latest filing, from 85.39% in the prior quarter.
- Across five years, Gross Margin topped out at 88.76% in Q1 2023 and bottomed at 85.38% in Q4 2023.
- The 5-year median for Gross Margin is 86.9% (2025), against an average of 86.88%.
- Across the five-year window, Gross Margin soared 79 bps in 2022 and tumbled 231 bps in 2023, its largest moves.
- Year by year, Gross Margin stood at 87.7% in 2022, then retreated by 3 bps to 85.38% in 2023, then increased by 0 bps to 85.46% in 2024, then declined by 0 bps to 85.39% in 2025, then rose by 2 bps to 86.85% in 2026.
- Per Business Quant, the three latest VRTX Gross Margin figures stand at 86.85% (Q1 2026), 85.39% (Q4 2025), and 86.52% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 88.95% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 90.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Alnylam Pharmaceuticals | 35.71 Bn | 32.70 Bn | 959.66 Mn | 82.22% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 86.85% |
| Dec 31, 2025 | 85.39% |
| Sep 30, 2025 | 86.52% |
| Jun 30, 2025 | 86.25% |
| Mar 31, 2025 | 86.90% |
| Dec 31, 2024 | 85.46% |
| Sep 30, 2024 | 85.84% |
| Jun 30, 2024 | 85.94% |
| Mar 31, 2024 | 87.27% |
| Dec 31, 2023 | 85.38% |
| Sep 30, 2023 | 87.17% |
| Jun 30, 2023 | 87.62% |
| Mar 31, 2023 | 88.76% |
| Dec 31, 2022 | 87.70% |
| Sep 30, 2022 | 87.60% |
| Jun 30, 2022 | 88.08% |
| Mar 31, 2022 | 88.28% |
| Dec 31, 2021 | 88.06% |
| Sep 30, 2021 | 88.08% |
| Jun 30, 2021 | 87.29% |