Ultragenyx Pharmaceutical Inc. (RARE) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

99,675,691Shares Outstanding

5,050,122Shares held by institutions

$101,911,462Value of institutional holdings

93.57%Institutional ownership %

9.31%Shares Changed QoQ

270No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Ultragenyx Pharmaceutical Inc. (NASDAQ:RARE) is held by 270 institutional firms.

The collective stake of institutional investors in Ultragenyx Pharmaceutical moved to 93.6% in December 2025, a shift down from the 97.5% reported for September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 9.31%, with a year-over-year a decrease of 13.46% in the count of filers.
The latest 13F cycle for Ultragenyx Pharmaceutical reveals that of 270 total investors, 162 funds grew their exposure, whereas 82 reduced theirs and 26 made no changes.
Collectively, institutional investors increased their stake in Ultragenyx Pharmaceutical to 93.26Mn shares as of December 2025, a change that is up by 7.94Mn shares quarter on quarter and up 5.28Mn shares year over year.
With 10.26Mn shares, VANGUARD GROUP INC commands the largest institutional position in Ultragenyx Pharmaceutical as of December 31, 2025, equating to 10.30% of the company.
Among the most significant buyers of Ultragenyx Pharmaceutical during December 2025 were CITADEL ADVISORS LLC (2.00Mn), NORGES BANK (1.26Mn), MORGAN STANLEY (916.11K), FRONTIER CAPITAL MANAGEMENT CO LLC (895.99K), MILLENNIUM MANAGEMENT LLC (781.43K).
Leading sellers of Ultragenyx Pharmaceutical stock in December 2025 included FMR LLC (4.62Mn), DEUTSCHE BANK AG\ (946.63K), JACOBS LEVY EQUITY MANAGEMENT, INC (418.46K), Schonfeld Strategic Advisors LLC (402.97K), FRANKLIN RESOURCES INC (368.12K).
The top 10 institutional holders of Ultragenyx Pharmaceutical for the quarter ending December 2025 included VANGUARD GROUP INC (10.26Mn), BlackRock, Inc. (6.63Mn), STATE STREET CORP (4.30Mn), JPMORGAN CHASE & CO (3.97Mn), SANDS CAPITAL MANAGEMENT, LLC (3.49Mn), RTW INVESTMENTS, LP (3.00Mn), BAKER BROS. ADVISORS LP (2.77Mn), FMR LLC (2.67Mn), WELLINGTON MANAGEMENT GROUP LLP (2.46Mn), CITADEL ADVISORS LLC (2.33Mn).

270 Institutional Holders

5,050,122 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	10,263,815	131,087	1.29%	$236,067,745.00
BlackRock, Inc.	31 Dec, 2025	6,631,554	206,291	3.21%	$152,525,742.00
STATE STREET CORP	31 Dec, 2025	4,303,046	610,559	16.54%	$98,970,058.00
JPMORGAN CHASE & CO	31 Dec, 2025	3,974,030	-37,399	-0.93%	$91,402,705.00
SANDS CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,485,724	-284,129	-7.54%	$80,171,652.00
RTW INVESTMENTS, LP	31 Dec, 2025	3,000,139	-258,127	-7.92%	$69,003,197.00
BAKER BROS. ADVISORS LP	31 Dec, 2025	2,772,692	0	0.00%	$63,771,916.00
FMR LLC	31 Dec, 2025	2,666,249	-4,617,047	-63.39%	$61,323,732.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	2,461,910	516,781	26.57%	$56,623,930.00
CITADEL ADVISORS LLC	31 Dec, 2025	2,326,125	1,995,172	602.86%	$53,500,875.00
SUVRETTA CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,019,000	0	0.00%	$46,437,000.00
FRONTIER CAPITAL MANAGEMENT CO LLC	31 Dec, 2025	1,965,084	895,986	83.81%	$45,196,925.00
BNP Paribas Asset Management Holding S.A.	31 Dec, 2025	1,899,661	354,382	22.93%	$43,692.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,838,208	257,701	16.30%	$42,287,465.00
MORGAN STANLEY	31 Dec, 2025	1,826,295	916,112	100.65%	$42,004,816.00
JACOBS LEVY EQUITY MANAGEMENT, INC	31 Dec, 2025	1,749,268	-418,461	-19.30%	$40,233,164.00
Aberdeen Group plc	31 Dec, 2025	1,469,951	496,295	50.97%	$33,808,873.00
GW&K Investment Management, LLC	31 Dec, 2025	1,375,407	225,238	19.58%	$31,634.00
AQR CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,360,497	614,315	82.33%	$31,291,431.00
Rock Springs Capital Management LP	31 Dec, 2025	1,267,241	20,900	1.68%	$29,146,543.00

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