Pyxis Oncology PYXS
NASDAQ PYXS
$1.64 +0.01 (+0.61%)
At close: Nov 11, 2026 · 4:00 PM EST

Pyxis Oncology (PYXS) Return on Equity [ROE] (2021 - 2026)

Updated

Pyxis Oncology (PYXS) reported Return on Equity [ROE] of -258.52% for Q2 2026, down 154.76 percentage points from -103.77% a year earlier.

Analysis

Pyxis Oncology (PYXS) Return on Equity [ROE] (2021 - 2026) Analysis & Trends

For FY2025, Pyxis Oncology posted Return on Equity [ROE] of -91.45%, down 28.70 percentage points from FY2024.

  • Return on Equity [ROE] has a four-year change of -34.71 percentage points (FY2021 to FY2025).
  • By year, Return on Equity [ROE] came in at -62.75% in FY2024 (-11.18 pp), -51.58% in FY2023 (+5.62 pp), -57.19% in FY2022 (-0.45 pp) and -56.74% in FY2021.
  • The Q2 2026 figure ranks as the lowest quarterly Return on Equity [ROE] in data going back to Q4 2021.
  • Year over year, Return on Equity [ROE] gained in 1 of the last seven quarters, with an average year-over-year change of -58.08 percentage points.
  • The high point for year-over-year Return on Equity [ROE] in five years was Q2 2024 (a gain of 32.38 percentage points); the low point was Q2 2026 (a drop of 154.76 percentage points).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Eli Lilly 1,348.13 Bn 1,321.74 Bn 20.46 Bn 74.39%
2 Johnson & Johnson 675.90 Bn 595.76 Bn 17.30 Bn 19.33%
3 AbbVie 519.45 Bn 487.50 Bn 13.12 Bn -
4 Merck 364.95 Bn 327.95 Bn 13.19 Bn 5.63%
5 Novartis Ag 311.58 Bn 285.16 Bn - -
6 Astrazeneca 289.34 Bn 262.94 Bn 13.26 Bn 21.60%
7 Amgen 251.64 Bn 203.30 Bn 7.58 Bn 72.13%
8 Gilead Sciences 212.05 Bn 187.07 Bn 6.73 Bn -31.17%
9 Pfizer 167.35 Bn 115.00 Bn 12.56 Bn 4.66%
10 Pyxis Oncology 136.12 Mn -60.32 Mn - -329.16%
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2026 -329.16%
Jun 30, 2026 -415.50%
Mar 31, 2026 -193.17%
Dec 31, 2025 -130.52%
Sep 30, 2025 -124.49%
Jun 30, 2025 -100.86%
Mar 31, 2025 -84.99%
Dec 31, 2024 -56.28%
Sep 30, 2024 -35.18%
Jun 30, 2024 -33.46%
Mar 31, 2024 -37.80%
Dec 31, 2023 -55.93%
Sep 30, 2023 -66.66%
Jun 30, 2023 -66.57%
Mar 31, 2023 -68.94%
Dec 31, 2022 -69.07%
Sep 30, 2022 -50.43%
Jun 30, 2022 -38.15%
Mar 31, 2022 -26.41%
Dec 31, 2021 -73.41%
API Access

Pyxis Oncology Return on Equity [ROE] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PYXS&period=max&api_key=YOUR_API_KEY