Pyxis Oncology PYXS
NASDAQ PYXS
$1.76 -0.08 (-4.35%)
At close: Oct 21, 2026 · 4:00 PM EDT

Pyxis Oncology (PYXS) Return on Equity [ROE] (2021 - 2026)

Updated

Pyxis Oncology (PYXS) reported Return on Equity [ROE] of -258.52% for Q2 2026, down 154.76 percentage points from -103.77% a year earlier.

Analysis

Pyxis Oncology (PYXS) Return on Equity [ROE] (2021 - 2026) Analysis & Trends

For FY2025, Pyxis Oncology posted Return on Equity [ROE] of -91.45%, down 28.70 percentage points from FY2024.

  • Return on Equity [ROE] has a four-year change of -34.71 percentage points (FY2021 to FY2025).
  • By year, Return on Equity [ROE] came in at -62.75% in FY2024 (-11.18 pp), -51.58% in FY2023 (+5.62 pp), -57.19% in FY2022 (-0.45 pp) and -56.74% in FY2021.
  • The Q2 2026 figure ranks as the lowest quarterly Return on Equity [ROE] in data going back to Q4 2021.
  • Year over year, Return on Equity [ROE] gained in 1 of the last seven quarters, with an average year-over-year change of -58.08 percentage points.
  • The high point for year-over-year Return on Equity [ROE] in five years was Q2 2024 (a gain of 32.38 percentage points); the low point was Q2 2026 (a drop of 154.76 percentage points).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Eli Lilly 1,136.97 Bn 1,105.55 Bn 19.71 Bn 82.09%
2 Johnson & Johnson 619.72 Bn 538.25 Bn 17.26 Bn 25.32%
3 AbbVie 503.40 Bn 476.52 Bn 12.70 Bn -
4 Merck 370.15 Bn 324.53 Bn 12.21 Bn 7.21%
5 Novartis Ag 298.64 Bn 262.63 Bn 11.24 Bn 31.52%
6 Astrazeneca 261.07 Bn 234.76 Bn 12.86 Bn 21.39%
7 Amgen 237.00 Bn 192.40 Bn 7.24 Bn 83.75%
8 Gilead Sciences 191.24 Bn 165.43 Bn 6.22 Bn -18.38%
9 Pfizer 170.31 Bn 116.96 Bn 10.94 Bn 4.97%
10 Pyxis Oncology 112.79 Mn -152.27 Mn - -258.52%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -258.52%
Dec 31, 2025 -131.19%
Sep 30, 2025 -127.56%
Jun 30, 2025 -103.77%
Mar 31, 2025 -87.48%
Dec 31, 2024 -58.48%
Sep 30, 2024 -36.28%
Jun 30, 2024 -34.54%
Mar 31, 2024 -38.91%
Dec 31, 2023 -57.32%
Sep 30, 2023 -67.43%
Jun 30, 2023 -66.92%
Mar 31, 2023 -69.41%
Dec 31, 2022 -69.07%
Sep 30, 2022 -50.43%
Jun 30, 2022 -38.15%
Mar 31, 2022 -26.41%
Dec 31, 2021 -73.41%
API Access

Pyxis Oncology Return on Equity [ROE] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PYXS&period=max&api_key=YOUR_API_KEY