Pyxis Oncology PYXS
NASDAQ PYXS
$3.08 -0.04 (-1.44%)
As of: Aug 21, 2026 · 3:59 PM EDT

Pyxis Oncology (PYXS) Retained Earnings (2020 - 2026)

Pyxis Oncology (PYXS) posted quarterly Retained Earnings of $53000.0 for Q4 2025, down 99.99% year-over-year from $484.1 million in Q4 2024, and up 100.01% quarter-over-quarter from -$425.1 million in Q3 2025.

Pyxis Oncology (PYXS) Retained Earnings (2020 - 2026) Analysis & Trends

Pyxis Oncology (PYXS) has reported Retained Earnings for 6 consecutive years, with $53000.0 the latest figure, recorded in Q4 2025.

  • In Q4 2025, Retained Earnings fell 99.99% year-over-year to $53000.0; the TTM figure through Dec 2025 stood at $53000.0 (down 99.99% YoY), while the FY2025 annual figure was $53000.0, down 99.99% from the prior year.
  • Retained Earnings improved to $53000.0 in Q4 2025 per PYXS's latest filing, from -$425.1 million in the prior quarter.
  • Across five years, Retained Earnings topped out at $484.1 million in Q4 2024 and bottomed at -$425.1 million in Q3 2025.
  • Historically, Retained Earnings has averaged $83.6 million across 5 years, with a median of $176.5 million in 2021.
  • Annual changes were most pronounced in 2021 — Retained Earnings jumped 363816.49% — and 2025, when it slumped 188.33%.
  • Pyxis Oncology's Retained Earnings stood at $353.0 million in 2021, then gained by 5.73% to $373.2 million in 2022, then climbed by 10.34% to $411.8 million in 2023, then gained by 17.55% to $484.1 million in 2024, then plunged by 99.99% to $53000.0 in 2025.
  • Business Quant data shows PYXS's Retained Earnings at $53000.0 in Q4 2025, -$425.1 million in Q3 2025, and -$403.1 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 15.69 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 37.62 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 558.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 5.10 Bn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 13.05 Bn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn -6.33 Bn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 20.91 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 6.57 Bn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 4.38 Bn
10 Pyxis Oncology 198.37 Mn 165.38 Mn - 503.18 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 503.18 Mn
Dec 31, 2025 53,000.00
Sep 30, 2025 -425.07 Mn
Jun 30, 2025 -403.10 Mn
Mar 31, 2025 -384.70 Mn
Dec 31, 2024 484.08 Mn
Sep 30, 2024 481.26 Mn
Jun 30, 2024 476.62 Mn
Mar 31, 2024 -289.50 Mn
Dec 31, 2023 411.82 Mn
Sep 30, 2023 408.64 Mn
Jun 30, 2023 -247.58 Mn
Mar 31, 2023 -231.70 Mn
Dec 31, 2022 373.23 Mn
Sep 30, 2022 365.05 Mn
Jun 30, 2022 -148.70 Mn
Mar 31, 2022 356.58 Mn
Dec 31, 2021 353.00 Mn
Sep 30, 2021 -74.90 Mn
Dec 31, 2020 97,000.00