Pyxis Oncology (PYXS) Net Margin (2024 - 2025)

Pyxis Oncology (PYXS) reported Net Margin of 164.16% for Q4 2025, up 74.38% quarter-over-quarter from 640.82% in Q2 2025.

Pyxis Oncology (PYXS) Net Margin (2024 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has 2 years of Net Margin data on file, last reported at 164.16% in Q4 2025.

  • Net Margin for Q4 2025 came in at 164.16%, changed N/A year-over-year; the trailing twelve-month figure through Dec 2025 was 576.32% (down 8445.0% YoY), and the FY2025 annual result was 574.65%, down 9570.0% from the prior year.
  • Net Margin climbed to 164.16% in Q4 2025 per PYXS's latest filing, from 640.82% in the prior quarter.
  • Over five years, Net Margin peaked at 33.09% in Q1 2024 and troughed at 640.82% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.82%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 34.53%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Pyxis Oncology 125.84 Mn 108.95 Mn 8.65 Mn -164.16%

Historic Data

Download Data
DateValue
Dec 31, 2025 -164.16%
Jun 30, 2025 -640.82%
Mar 31, 2024 -33.09%