Vertex Pharmaceuticals (VRTX) Net Margin (2009 - 2026)

Vertex Pharmaceuticals' (VRTX) quarterly Net Margin came in at 34.53% in Q1 2026, up 1120.0% year-on-year from 2.83% in Q1 2025, and down 7.52% quarter-over-quarter from 37.34% in Q4 2025.

Vertex Pharmaceuticals (VRTX) Net Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Net Margin history runs 17 years deep, the most recent figure standing at 34.53% for Q1 2026.

  • On a quarterly basis, Net Margin rose 1120.0% year-over-year to 34.53% in Q1 2026; TTM through Mar 2026 was 35.51%, a 4442.0% increase from a year earlier, with the FY2025 full-year figure at 32.94%, up 3780.0% from the prior year.
  • Net Margin slipped to 34.53% in Q1 2026 per VRTX's latest filing, from 37.34% in the prior quarter.
  • Across five years, Net Margin topped out at 41.69% in Q3 2023 and bottomed at 135.83% in Q2 2024.
  • The 5-year median for Net Margin is 36.33% (2022), against an average of 25.55%.
  • Across the five-year window, Net Margin tumbled 17256 bps in 2024 and soared 17067 bps in 2025, its largest moves.
  • Year by year, Net Margin stood at 35.56% in 2022, then advanced by 8 bps to 38.48% in 2023, then fell by 19 bps to 31.35% in 2024, then grew by 19 bps to 37.34% in 2025, then declined by 8 bps to 34.53% in 2026.
  • Per Business Quant, the three latest VRTX Net Margin figures stand at 34.53% (Q1 2026), 37.34% (Q4 2025), and 35.2% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 15.02%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 20.17%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 30.33%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn 17.65%

Historic Data

Download Data
DateValue
Mar 31, 2026 34.53%
Dec 31, 2025 37.34%
Sep 30, 2025 35.20%
Jun 30, 2025 34.84%
Mar 31, 2025 23.33%
Dec 31, 2024 31.35%
Sep 30, 2024 37.71%
Jun 30, 2024 -135.83%
Mar 31, 2024 40.87%
Dec 31, 2023 38.48%
Sep 30, 2023 41.69%
Jun 30, 2023 36.73%
Mar 31, 2023 29.47%
Dec 31, 2022 35.56%
Sep 30, 2022 39.86%
Jun 30, 2022 36.90%
Mar 31, 2022 36.33%
Dec 31, 2021 37.16%
Sep 30, 2021 42.94%
Jun 30, 2021 3.74%