Growth Metrics

Vertex Pharmaceuticals (VRTX) Net Margin (2016 - 2025)

Vertex Pharmaceuticals has reported Net Margin over the past 17 years, most recently at 37.34% for Q4 2025.

  • Quarterly results put Net Margin at 37.34% for Q4 2025, up 599.0% from a year ago — trailing twelve months through Dec 2025 was 32.94% (up 3780.0% YoY), and the annual figure for FY2025 was 32.94%, up 3780.0%.
  • Net Margin for Q4 2025 was 37.34% at Vertex Pharmaceuticals, up from 35.2% in the prior quarter.
  • Over the last five years, Net Margin for VRTX hit a ceiling of 42.94% in Q3 2021 and a floor of 135.83% in Q2 2024.
  • Median Net Margin over the past 5 years was 36.82% (2022), compared with a mean of 26.08%.
  • Biggest five-year swings in Net Margin: plummeted -17256bps in 2024 and later soared 17067bps in 2025.
  • Vertex Pharmaceuticals' Net Margin stood at 37.16% in 2021, then dropped by -4bps to 35.56% in 2022, then increased by 8bps to 38.48% in 2023, then dropped by -19bps to 31.35% in 2024, then increased by 19bps to 37.34% in 2025.
  • The last three reported values for Net Margin were 37.34% (Q4 2025), 35.2% (Q3 2025), and 34.84% (Q2 2025) per Business Quant data.