Vertex Pharmaceuticals (VRTX) Net Margin (2009 - 2026)

Vertex Pharmaceuticals (VRTX) posted quarterly Net Margin of 34.53% for Q1 2026, up 1120.0% year-over-year from 2.83% in Q1 2025, and down 7.52% quarter-over-quarter from 37.34% in Q4 2025.

Vertex Pharmaceuticals (VRTX) Net Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Net Margin history runs 17 years deep, the most recent figure standing at 34.53% for Q1 2026.

  • In Q1 2026, Net Margin rose 1120.0% year-over-year to 34.53%; the TTM figure through Mar 2026 stood at 35.51% (up 4442.0% YoY), while the FY2025 annual figure was 32.94%, up 3780.0% from the prior year.
  • Net Margin for Q1 2026 stood at 34.53%, down from 37.34% in the prior quarter.
  • The five-year high for Net Margin was 41.69% in Q3 2023, with the low at 135.83% in Q2 2024.
  • The 5-year median for Net Margin is 36.33% (2022), against an average of 25.55%.
  • The sharpest annual moves came in 2024 and 2025: Net Margin slumped 17256 bps in 2024, then soared 17067 bps in 2025.
  • Vertex Pharmaceuticals' Net Margin stood at 35.56% in 2022, then gained by 8 bps to 38.48% in 2023, then declined by 19 bps to 31.35% in 2024, then climbed by 19 bps to 37.34% in 2025, then dropped by 8 bps to 34.53% in 2026.
  • Business Quant data shows VRTX's Net Margin at 34.53% in Q1 2026, 37.34% in Q4 2025, and 35.2% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 Roivant Sciences 26.16 Bn 26.85 Bn 1.16 Mn -20,152.98%

Historic Data

Download Data
DateValue
Jun 30, 2026 32.99%
Mar 31, 2026 34.53%
Dec 31, 2025 37.34%
Sep 30, 2025 35.20%
Jun 30, 2025 34.84%
Mar 31, 2025 23.33%
Dec 31, 2024 31.35%
Sep 30, 2024 37.71%
Jun 30, 2024 -135.83%
Mar 31, 2024 40.87%
Dec 31, 2023 38.48%
Sep 30, 2023 41.69%
Jun 30, 2023 36.73%
Mar 31, 2023 29.47%
Dec 31, 2022 35.56%
Sep 30, 2022 39.86%
Jun 30, 2022 36.90%
Mar 31, 2022 36.33%
Dec 31, 2021 37.16%
Sep 30, 2021 42.94%