Vertex Pharmaceuticals (VRTX) Net Margin (2009 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Net Margin of 34.53% in Q1 2026, down 7.52% quarter-over-quarter from 37.34% in Q4 2025, and up 1120.0% on a YoY basis from 2.83% in Q1 2025.

Vertex Pharmaceuticals (VRTX) Net Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Net Margin history runs 18 years deep, the most recent figure standing at 34.53% for Q1 2026.

  • In Q1 2026, Net Margin rose 1120.0% year-over-year to 34.53%; the TTM figure through Mar 2026 stood at 35.51% (up 4442.0% YoY), while the FY2025 annual figure was 32.94%, up 3780.0% from the prior year.
  • Net Margin was 34.53% for Q1 2026 at Vertex Pharmaceuticals, down from 37.34% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 41.69% in Q3 2023 to a low of 135.83% in Q2 2024.
  • Historically, Net Margin has averaged 25.55% across 5 years, with a median of 36.33% in 2022.
  • The sharpest annual moves came in 2024 and 2025: Net Margin tumbled 17256 bps in 2024, then jumped 17067 bps in 2025.
  • A 5-year view of Net Margin shows it stood at 35.56% in 2022, then grew by 8 bps to 38.48% in 2023, then fell by 19 bps to 31.35% in 2024, then grew by 19 bps to 37.34% in 2025, then declined by 8 bps to 34.53% in 2026.
  • The last three Net Margin figures came in at 34.53% (Q1 2026), 37.34% (Q4 2025), and 35.2% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.82%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 34.53%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn 20.17%

Historic Data

Download Data
DateValue
Mar 31, 2026 34.53%
Dec 31, 2025 37.34%
Sep 30, 2025 35.20%
Jun 30, 2025 34.84%
Mar 31, 2025 23.33%
Dec 31, 2024 31.35%
Sep 30, 2024 37.71%
Jun 30, 2024 -135.83%
Mar 31, 2024 40.87%
Dec 31, 2023 38.48%
Sep 30, 2023 41.69%
Jun 30, 2023 36.73%
Mar 31, 2023 29.47%
Dec 31, 2022 35.56%
Sep 30, 2022 39.86%
Jun 30, 2022 36.90%
Mar 31, 2022 36.33%
Dec 31, 2021 37.16%
Sep 30, 2021 42.94%
Jun 30, 2021 3.74%