Growth Metrics

Vertex Pharmaceuticals (VRTX) Net Margin (2016 - 2025)

Vertex Pharmaceuticals (VRTX) has 17 years of Net Margin data on record, last reported at 37.34% in Q4 2025.

  • For Q4 2025, Net Margin rose 599.0% year-over-year to 37.34%; the TTM value through Dec 2025 reached 32.94%, up 3780.0%, while the annual FY2025 figure was 32.94%, 3780.0% up from the prior year.
  • Net Margin reached 37.34% in Q4 2025 per VRTX's latest filing, up from 35.2% in the prior quarter.
  • Across five years, Net Margin topped out at 42.94% in Q3 2021 and bottomed at 135.83% in Q2 2024.
  • Average Net Margin over 5 years is 26.08%, with a median of 36.82% recorded in 2022.
  • Peak YoY movement for Net Margin: tumbled -17256bps in 2024, then skyrocketed 17067bps in 2025.
  • A 5-year view of Net Margin shows it stood at 37.16% in 2021, then fell by -4bps to 35.56% in 2022, then grew by 8bps to 38.48% in 2023, then fell by -19bps to 31.35% in 2024, then grew by 19bps to 37.34% in 2025.
  • Per Business Quant database, its latest 3 readings for Net Margin were 37.34% in Q4 2025, 35.2% in Q3 2025, and 34.84% in Q2 2025.