Pyxis Oncology PYXS
NASDAQ PYXS
$1.76 -0.08 (-4.35%)
At close: Oct 21, 2026 · 4:00 PM EDT

Pyxis Oncology (PYXS) EBITDA (2020 - 2025)

Updated

Pyxis Oncology's EBITDA came in at -$15.4 million for Q4 2025, compared with -$39.52 million a year earlier.

Analysis

Pyxis Oncology (PYXS) EBITDA (2020 - 2025) Analysis & Trends

For FY2025, Pyxis Oncology's EBITDA was -$79.91 million.

  • Going back by year, EBITDA was -$86.48 million in FY2024, -$80.27 million in FY2023, -$122.77 million in FY2022 and -$69.07 million in FY2021.
  • The Q4 2025 figure represents the highest quarterly EBITDA since Q1 2024.
  • Business Quant data shows PYXS's EBITDA at -$22.93 million (Q3 2025), -$19.22 million (Q2 2025) and -$22.36 million (Q1 2025) in the three quarters before Q4 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Eli Lilly 1,136.97 Bn 1,105.55 Bn 19.71 Bn 12.29 Bn
2 Johnson & Johnson 619.72 Bn 538.25 Bn 17.26 Bn 9.10 Bn
3 AbbVie 503.40 Bn 476.52 Bn 12.70 Bn 8.33 Bn
4 Merck 370.15 Bn 324.53 Bn 12.21 Bn 999.00 Mn
5 Novartis Ag 298.64 Bn 262.63 Bn 11.24 Bn -
6 Astrazeneca 261.07 Bn 234.76 Bn 12.86 Bn 5.09 Bn
7 Amgen 237.00 Bn 192.40 Bn 7.24 Bn 4.63 Bn
8 Gilead Sciences 191.24 Bn 165.43 Bn 6.22 Bn -9.70 Bn
9 Pfizer 170.31 Bn 116.96 Bn 10.94 Bn 5.89 Bn
10 Pyxis Oncology 112.79 Mn -152.27 Mn - -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 -15.40 Mn
Sep 30, 2025 -22.93 Mn
Jun 30, 2025 -19.22 Mn
Mar 31, 2025 -22.36 Mn
Dec 31, 2024 -39.52 Mn
Sep 30, 2024 -23.02 Mn
Jun 30, 2024 -19.45 Mn
Mar 31, 2024 -4.49 Mn
Dec 31, 2023 -17.08 Mn
Sep 30, 2023 -24.83 Mn
Jun 30, 2023 -17.60 Mn
Mar 31, 2023 -20.76 Mn
Dec 31, 2022 -37.78 Mn
Sep 30, 2022 -28.19 Mn
Jun 30, 2022 -25.57 Mn
Mar 31, 2022 -31.23 Mn
Dec 31, 2021 -16.27 Mn
Sep 30, 2021 -11.46 Mn
Jun 30, 2021 -5.72 Mn
Mar 31, 2021 -35.62 Mn
API Access

Pyxis Oncology EBITDA API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=ebitda&ticker=PYXS&period=max&api_key=YOUR_API_KEY