Pyxis Oncology (PYXS) EBITDA (2020 - 2026)
Pyxis Oncology's EBITDA came in at -$15.4 million for Q4 2025, compared with -$39.52 million a year earlier.
Powered by 
Analysis
Pyxis Oncology (PYXS) EBITDA (2020 - 2026) Analysis & Trends
For FY2025, Pyxis Oncology's EBITDA was -$79.91 million.
- Going back by year, EBITDA was -$86.48 million in FY2024, -$80.27 million in FY2023, -$122.77 million in FY2022 and -$69.07 million in FY2021.
- The Q4 2025 figure represents the highest quarterly EBITDA since Q1 2024.
- Business Quant data shows PYXS's EBITDA at -$22.93 million (Q3 2025), -$19.22 million (Q2 2025) and -$22.36 million (Q1 2025) in the three quarters before Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 8.95 Bn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 8.30 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 8.16 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 7.34 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 5.99 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 4.83 Bn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 4.20 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 7.05 Bn |
| 10 | Pyxis Oncology | 136.12 Mn | -60.32 Mn | - | -20.22 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -20.22 Mn |
| Jun 30, 2026 | -25.69 Mn |
| Mar 31, 2026 | -23.90 Mn |
| Dec 31, 2025 | -15.40 Mn |
| Sep 30, 2025 | -22.93 Mn |
| Jun 30, 2025 | -19.22 Mn |
| Mar 31, 2025 | -22.36 Mn |
| Dec 31, 2024 | -39.52 Mn |
| Sep 30, 2024 | -23.02 Mn |
| Jun 30, 2024 | -19.45 Mn |
| Mar 31, 2024 | -4.49 Mn |
| Dec 31, 2023 | -17.08 Mn |
| Sep 30, 2023 | -24.83 Mn |
| Jun 30, 2023 | -17.60 Mn |
| Mar 31, 2023 | -20.76 Mn |
| Dec 31, 2022 | -37.78 Mn |
| Sep 30, 2022 | -28.19 Mn |
| Jun 30, 2022 | -25.57 Mn |
| Mar 31, 2022 | -31.23 Mn |
| Dec 31, 2021 | -16.27 Mn |
API Access
Pyxis Oncology EBITDA API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda&ticker=PYXS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda", "ticker": "PYXS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda&ticker=PYXS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();