Pyxis Oncology PYXS
NASDAQ PYXS
$3.26 -0.12 (-3.61%)
As of: Sep 10, 2026 · 2:43 PM EDT

Pyxis Oncology (PYXS) EBITDA (2020 - 2026)

Pyxis Oncology's (PYXS) quarterly EBITDA came in at -$26.0 million in Q2 2026, down 31.59% year-over-year from -$38.0 million in Q2 2025, and down 42.06% quarter-over-quarter from -$18.3 million in Q4 2025.

Analysis

Pyxis Oncology (PYXS) EBITDA (2020 - 2026) Analysis & Trends

Pyxis Oncology (PYXS) has reported EBITDA for 7 consecutive years, with -$26.0 million the latest figure, recorded in Q2 2026.

  • On a quarterly basis, EBITDA fell 31.59% year-over-year to -$26.0 million in Q2 2026; TTM through Jun 2026 was -$87.5 million, a 17.83% increase from a year earlier, with the FY2025 full-year figure at -$84.4 million, up 5.63% from the prior year.
  • EBITDA was -$26.0 million for Q2 2026 at Pyxis Oncology, down from -$18.3 million in the prior quarter.
  • Over five years, EBITDA peaked at -$5.6 million in Q1 2024 and troughed at -$40.1 million in Q4 2024.
  • A 5-year average of -$23.9 million and a median of -$23.5 million in 2025 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA plunged 333.02% in 2022 and soared 73.25% in 2024, its largest moves.
  • Over 5 years, EBITDA stood at -$38.0 million in 2022, then surged by 53.21% to -$17.8 million in 2023, then plunged by 125.52% to -$40.1 million in 2024, then surged by 54.34% to -$18.3 million in 2025, then plunged by 42.06% to -$26.0 million in 2026.
  • The last three EBITDA figures came in at -$26.0 million (Q2 2026), -$18.3 million (Q4 2025), and -$23.5 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Amgen 206.12 Bn 192.13 Bn 7.24 Bn 3.51 Bn
2 Gilead Sciences 180.16 Bn 176.98 Bn 6.22 Bn -10.39 Bn
3 Vertex Pharmaceuticals 131.52 Bn 123.67 Bn 2.84 Bn 1.25 Bn
4 Regeneron Pharmaceuticals 81.95 Bn 73.96 Bn 3.93 Bn 1.29 Bn
5 Argenx Se 60.36 Bn 55.18 Bn 1.37 Bn 493.00 Mn
6 Moderna 53.81 Bn 48.67 Bn 52.00 Mn -815.00 Mn
7 Alnylam Pharmaceuticals 33.01 Bn 29.70 Bn 992.69 Mn 231.44 Mn
8 Biogen 31.96 Bn 30.67 Bn 1.96 Bn -644.50 Mn
9 Roivant Sciences 29.25 Bn 29.25 Bn 1.16 Mn -365.99 Mn
10 Pyxis Oncology 208.29 Mn 175.30 Mn - -25.99 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -25.99 Mn
Dec 31, 2025 -18.30 Mn
Sep 30, 2025 -23.46 Mn
Jun 30, 2025 -19.75 Mn
Mar 31, 2025 -22.91 Mn
Dec 31, 2024 -40.07 Mn
Sep 30, 2024 -23.75 Mn
Jun 30, 2024 -20.03 Mn
Mar 31, 2024 -5.61 Mn
Dec 31, 2023 -17.77 Mn
Sep 30, 2023 -25.35 Mn
Jun 30, 2023 -18.12 Mn
Mar 31, 2023 -20.95 Mn
Dec 31, 2022 -37.97 Mn
Sep 30, 2022 -28.39 Mn
Jun 30, 2022 -25.73 Mn
Mar 31, 2022 -31.39 Mn
Dec 31, 2021 -16.43 Mn
Sep 30, 2021 -11.62 Mn
Jun 30, 2021 -5.94 Mn