Pyxis Oncology (PYXS) Change in Cash (2020 - 2025)
Pyxis Oncology's (PYXS) quarterly Change in Cash came in at $6.5 million in Q4 2025, down 12.32% year-on-year from $7.4 million in Q4 2024, and up 458.49% on a QoQ basis from -$1.8 million in Q3 2025.
Pyxis Oncology (PYXS) Change in Cash (2020 - 2025) Analysis & Trends
Pyxis Oncology (PYXS) has 6 years of Change in Cash data on file, last reported at $6.5 million in Q4 2025.
- On a quarterly basis, Change in Cash fell 12.32% year-over-year to $6.5 million in Q4 2025; TTM through Dec 2025 was -$4.1 million, a 141.3% decrease from a year earlier, with the FY2025 full-year figure at -$4.1 million, down 141.3% from the prior year.
- Change in Cash for Q4 2025 stood at $6.5 million, up from -$1.8 million in the prior quarter.
- Over the last five years, Change in Cash for PYXS reached as high as $142.7 million in Q4 2021 and fell as low as -$126.2 million in Q1 2023.
- Historically, Change in Cash has averaged $435300.0 across 5 years, with a median of -$5.9 million in 2023.
- Across the five-year window, Change in Cash soared 4608.24% in 2021 and plunged 1417.86% in 2022, its largest moves.
- Year by year, Change in Cash stood at $142.7 million in 2021, then slumped by 113.48% to -$19.2 million in 2022, then soared by 73.75% to -$5.1 million in 2023, then jumped by 246.84% to $7.4 million in 2024, then dropped by 12.32% to $6.5 million in 2025.
- Per Business Quant data, the three most recent Change in Cash figures were $6.5 million in Q4 2025, -$1.8 million in Q3 2025, and -$2.0 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -22.03 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 243.78 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -1.34 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 417.10 Mn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -153.10 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 57.19 Mn |
| 10 | Pyxis Oncology | 166.54 Mn | 99.69 Mn | 8.65 Mn | 6.50 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 6.50 Mn |
| Sep 30, 2025 | -1.81 Mn |
| Jun 30, 2025 | -2.03 Mn |
| Mar 31, 2025 | -6.71 Mn |
| Dec 31, 2024 | 7.42 Mn |
| Sep 30, 2024 | -13.02 Mn |
| Jun 30, 2024 | -2.89 Mn |
| Mar 31, 2024 | 18.30 Mn |
| Dec 31, 2023 | -5.05 Mn |
| Sep 30, 2023 | -11.18 Mn |
| Jun 30, 2023 | -27.16 Mn |
| Mar 31, 2023 | -126.23 Mn |
| Dec 31, 2022 | -19.25 Mn |
| Sep 30, 2022 | -24.82 Mn |
| Jun 30, 2022 | -23.84 Mn |
| Mar 31, 2022 | -27.65 Mn |
| Dec 31, 2021 | 142.73 Mn |
| Sep 30, 2021 | -9.00 Mn |
| Jun 30, 2021 | 1.81 Mn |
| Mar 31, 2021 | 132.58 Mn |