Pyxis Oncology (PYXS) Cash from Operations (2020 - 2025)

Pyxis Oncology's (PYXS) quarterly Cash from Operations came in at 10427000.0 in Q4 2025, up 45.95% year-on-year from 7144419.07 in Q4 2024, and up 21.47% on a QoQ basis from 13277000.0 in Q3 2025.

Pyxis Oncology (PYXS) Cash from Operations (2020 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has 6 years of Cash from Operations data on file, last reported at 10427000.0 in Q4 2025.

  • On a quarterly basis, Cash from Operations rose 45.95% year-over-year to 10427000.0 in Q4 2025; TTM through Dec 2025 was 63502000.0, a 10.11% decrease from a year earlier, with the FY2025 full-year figure at 63502000.0, down 10.11% from the prior year.
  • Cash from Operations for Q4 2025 stood at 10427000.0, up from 13277000.0 in the prior quarter.
  • Over the last five years, Cash from Operations for PYXS reached as high as 2862000.0 in Q2 2021 and fell as low as 27679000.0 in Q1 2022.
  • Historically, Cash from Operations has averaged 15827200.0 across 5 years, with a median of 17325000.0 in 2022.
  • Across the five-year window, Cash from Operations slumped 928.51% in 2022 and jumped 72.74% in 2024, its largest moves.
  • Year by year, Cash from Operations stood at 12169000.0 in 2021, then sank by 42.88% to 17387000.0 in 2022, then increased by 12.27% to 15254000.0 in 2023, then retreated by 26.46% to 19290000.0 in 2024, then surged by 45.95% to 10427000.0 in 2025.
  • Per Business Quant data, the three most recent Cash from Operations figures were 10427000.0 in Q4 2025, 13277000.0 in Q3 2025, and 17263000.0 in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Operations (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.59 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 201.34 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.43 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 1.08 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.17 Mn
10 Pyxis Oncology 166.54 Mn 99.69 Mn 8.65 Mn -10.43 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -10.43 Mn
Dec 31, 2025 -10.43 Mn
Sep 30, 2025 -13.28 Mn
Sep 30, 2025 -13.28 Mn
Jun 30, 2025 -17.26 Mn
Jun 30, 2025 -17.26 Mn
Mar 31, 2025 -22.54 Mn
Mar 31, 2025 -22.54 Mn
Dec 31, 2024 -19.29 Mn
Dec 31, 2024 -19.29 Mn
Sep 30, 2024 -14.67 Mn
Sep 30, 2024 -14.67 Mn
Jun 30, 2024 -3.01 Mn
Jun 30, 2024 -3.01 Mn
Mar 31, 2024 -20.71 Mn
Mar 31, 2024 -20.71 Mn
Dec 31, 2023 -15.25 Mn
Dec 31, 2023 -15.25 Mn
Sep 30, 2023 -17.58 Mn
Sep 30, 2023 -17.58 Mn