Pyxis Oncology (PYXS) Cash from Operations (2020 - 2025)
Pyxis Oncology (PYXS) reported Cash from Operations of 10427000.0 for Q4 2025, up 45.95% year-over-year from 7144419.07 in Q4 2024, and up 21.47% quarter-over-quarter from 13277000.0 in Q3 2025.
Pyxis Oncology (PYXS) Cash from Operations (2020 - 2025) Analysis & Trends
Pyxis Oncology (PYXS) has 6 years of Cash from Operations data on file, last reported at 10427000.0 in Q4 2025.
- Cash from Operations for Q4 2025 came in at 10427000.0, up 45.95% year-over-year; the trailing twelve-month figure through Dec 2025 was 63502000.0 (down 10.11% YoY), and the FY2025 annual result was 63502000.0, down 10.11% from the prior year.
- Cash from Operations rose to 10427000.0 in Q4 2025 per PYXS's latest filing, from 13277000.0 in the prior quarter.
- Over five years, Cash from Operations peaked at 2862000.0 in Q2 2021 and troughed at 27679000.0 in Q1 2022.
- A 5-year average of 15827200.0 and a median of 17325000.0 in 2022 frame the typical range for Cash from Operations.
- The sharpest annual moves came in 2022 and 2024: Cash from Operations plunged 928.51% in 2022, then soared 72.74% in 2024.
- A 5-year view of Cash from Operations shows it stood at 12169000.0 in 2021, then plunged by 42.88% to 17387000.0 in 2022, then advanced by 12.27% to 15254000.0 in 2023, then dropped by 26.46% to 19290000.0 in 2024, then surged by 45.95% to 10427000.0 in 2025.
- Business Quant data shows PYXS's Cash from Operations at 10427000.0 in Q4 2025, 13277000.0 in Q3 2025, and 17263000.0 in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Ops. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -1.67 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -12.20 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.49 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.43 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Pyxis Oncology | 125.84 Mn | 108.95 Mn | 8.65 Mn | -10.43 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -10.43 Mn |
| Dec 31, 2025 | -10.43 Mn |
| Sep 30, 2025 | -13.28 Mn |
| Sep 30, 2025 | -13.28 Mn |
| Jun 30, 2025 | -17.26 Mn |
| Jun 30, 2025 | -17.26 Mn |
| Mar 31, 2025 | -22.54 Mn |
| Mar 31, 2025 | -22.54 Mn |
| Dec 31, 2024 | -19.29 Mn |
| Dec 31, 2024 | -19.29 Mn |
| Sep 30, 2024 | -14.67 Mn |
| Sep 30, 2024 | -14.67 Mn |
| Jun 30, 2024 | -3.01 Mn |
| Jun 30, 2024 | -3.01 Mn |
| Mar 31, 2024 | -20.71 Mn |
| Mar 31, 2024 | -20.71 Mn |
| Dec 31, 2023 | -15.25 Mn |
| Dec 31, 2023 | -15.25 Mn |
| Sep 30, 2023 | -17.58 Mn |
| Sep 30, 2023 | -17.58 Mn |