Pyxis Oncology PYXS
NASDAQ PYXS
$3.08 -0.04 (-1.28%)
At close: Aug 21, 2026 · 4:00 PM EDT

Pyxis Oncology (PYXS) Cash from Investing Activities (2021 - 2025)

Pyxis Oncology (PYXS) posted quarterly Cash from Investing Activities of $16.3 million for Q4 2025, down 39.0% year-over-year from $26.7 million in Q4 2024, and up 41.76% quarter-over-quarter from $11.5 million in Q3 2025.

Pyxis Oncology (PYXS) Cash from Investing Activities (2021 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has reported Cash from Investing Activities for 5 consecutive years, with $16.3 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Cash from Investing Activities fell 39.0% year-over-year to $16.3 million; the TTM figure through Dec 2025 stood at $58.9 million (up 621.73% YoY), while the FY2025 annual figure was $58.9 million, up 621.73% from the prior year.
  • Cash from Investing Activities rose to $16.3 million in Q4 2025 per PYXS's latest filing, from $11.5 million in the prior quarter.
  • Across five years, Cash from Investing Activities topped out at $26.7 million in Q4 2024 and bottomed at -$99.4 million in Q1 2023.
  • Historically, Cash from Investing Activities has averaged -$2.5 million across 5 years, with a median of -$68500.0 in 2022.
  • Annual changes were most pronounced in 2023 — Cash from Investing Activities sank 67977.4% — and 2025, when it surged 382500.0%.
  • Pyxis Oncology's Cash from Investing Activities stood at -$371000.0 in 2021, then tumbled by 400.81% to -$1.9 million in 2022, then soared by 650.48% to $10.2 million in 2023, then soared by 160.63% to $26.7 million in 2024, then plunged by 39.0% to $16.3 million in 2025.
  • Business Quant data shows PYXS's Cash from Investing Activities at $16.3 million in Q4 2025, $11.5 million in Q3 2025, and $15.3 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn -45.80 Mn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn -92.70 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 329.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn -49.35 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn -363.46 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -3.17 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 24.51 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - -229.72 Mn
10 Pyxis Oncology 198.37 Mn 165.38 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 16.26 Mn
Dec 31, 2025 16.26 Mn
Sep 30, 2025 11.47 Mn
Sep 30, 2025 11.47 Mn
Jun 30, 2025 15.30 Mn
Jun 30, 2025 15.30 Mn
Mar 31, 2025 15.82 Mn
Mar 31, 2025 15.82 Mn
Dec 31, 2024 26.66 Mn
Dec 31, 2024 26.66 Mn
Sep 30, 2024 -8,000.00
Sep 30, 2024 -8,000.00
Jun 30, 2024 4,000.00
Jun 30, 2024 4,000.00
Mar 31, 2024 -18.50 Mn
Mar 31, 2024 -18.50 Mn
Dec 31, 2023 10.23 Mn
Dec 31, 2023 10.23 Mn
Sep 30, 2023 6.57 Mn
Sep 30, 2023 6.57 Mn