Pyxis Oncology (PYXS) Cash from Investing Activities (2021 - 2025)
Pyxis Oncology (PYXS) posted quarterly Cash from Investing Activities of $16.3 million for Q4 2025, down 39.0% year-over-year from $26.7 million in Q4 2024, and up 41.76% quarter-over-quarter from $11.5 million in Q3 2025.
Pyxis Oncology (PYXS) Cash from Investing Activities (2021 - 2025) Analysis & Trends
Pyxis Oncology (PYXS) has reported Cash from Investing Activities for 5 consecutive years, with $16.3 million the latest figure, recorded in Q4 2025.
- In Q4 2025, Cash from Investing Activities fell 39.0% year-over-year to $16.3 million; the TTM figure through Dec 2025 stood at $58.9 million (up 621.73% YoY), while the FY2025 annual figure was $58.9 million, up 621.73% from the prior year.
- Cash from Investing Activities rose to $16.3 million in Q4 2025 per PYXS's latest filing, from $11.5 million in the prior quarter.
- Across five years, Cash from Investing Activities topped out at $26.7 million in Q4 2024 and bottomed at -$99.4 million in Q1 2023.
- Historically, Cash from Investing Activities has averaged -$2.5 million across 5 years, with a median of -$68500.0 in 2022.
- Annual changes were most pronounced in 2023 — Cash from Investing Activities sank 67977.4% — and 2025, when it surged 382500.0%.
- Pyxis Oncology's Cash from Investing Activities stood at -$371000.0 in 2021, then tumbled by 400.81% to -$1.9 million in 2022, then soared by 650.48% to $10.2 million in 2023, then soared by 160.63% to $26.7 million in 2024, then plunged by 39.0% to $16.3 million in 2025.
- Business Quant data shows PYXS's Cash from Investing Activities at $16.3 million in Q4 2025, $11.5 million in Q3 2025, and $15.3 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Investing Activities (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.13 Bn | 131.28 Bn | 2.84 Bn | -45.80 Mn |
| 2 | Regeneron Pharmaceuticals | 85.77 Bn | 77.77 Bn | 3.93 Bn | -92.70 Mn |
| 3 | Argenx Se | 64.64 Bn | 59.46 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.29 Bn | 53.16 Bn | 52.00 Mn | 329.00 Mn |
| 5 | BeOne Medicines | 41.92 Bn | 36.82 Bn | 1.53 Bn | -49.35 Mn |
| 6 | Alnylam Pharmaceuticals | 31.58 Bn | 28.28 Bn | 992.69 Mn | -363.46 Mn |
| 7 | BioNTech SE | 28.12 Bn | 9.73 Bn | 668.28 Mn | -3.17 Bn |
| 8 | Insmed | 27.39 Bn | 26.22 Bn | 358.27 Mn | 24.51 Mn |
| 9 | Royalty Pharma | 27.27 Bn | 26.43 Bn | - | -229.72 Mn |
| 10 | Pyxis Oncology | 198.37 Mn | 165.38 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 16.26 Mn |
| Dec 31, 2025 | 16.26 Mn |
| Sep 30, 2025 | 11.47 Mn |
| Sep 30, 2025 | 11.47 Mn |
| Jun 30, 2025 | 15.30 Mn |
| Jun 30, 2025 | 15.30 Mn |
| Mar 31, 2025 | 15.82 Mn |
| Mar 31, 2025 | 15.82 Mn |
| Dec 31, 2024 | 26.66 Mn |
| Dec 31, 2024 | 26.66 Mn |
| Sep 30, 2024 | -8,000.00 |
| Sep 30, 2024 | -8,000.00 |
| Jun 30, 2024 | 4,000.00 |
| Jun 30, 2024 | 4,000.00 |
| Mar 31, 2024 | -18.50 Mn |
| Mar 31, 2024 | -18.50 Mn |
| Dec 31, 2023 | 10.23 Mn |
| Dec 31, 2023 | 10.23 Mn |
| Sep 30, 2023 | 6.57 Mn |
| Sep 30, 2023 | 6.57 Mn |