Growth Metrics

Palvella Therapeutics (PVLA) Operating Expenses (2013 - 2026)

Palvella Therapeutics (PVLA) reported Operating Expenses of $14.9 million for Q1 2026, up 88.73% year-over-year from $7.9 million in Q1 2025, and up 31.41% on a QoQ basis from $11.3 million in Q4 2025.

Palvella Therapeutics (PVLA) has 14 years of Operating Expenses data on file, last reported at $14.9 million in Q1 2026.

  • Quarterly Operating Expenses rose 88.73% year-over-year to $14.9 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $45.6 million (up 125.6% YoY) and the FY2025 annual result came in at $38.6 million, up 173.87% from the prior year.
  • Operating Expenses advanced to $14.9 million in Q1 2026 per PVLA's latest filing, from $11.3 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $31.3 million in Q3 2023 and bottomed at -$54.9 million in Q4 2023.
  • The 5-year median for Operating Expenses is $10.7 million (2025), against an average of $8.2 million.
  • The widest annual swing landed in 2024, when Operating Expenses sank 89.92%; it then soared 347.47% in 2025.
  • Tracing PVLA's Operating Expenses over 5 years: stood at $17.5 million in 2022, then plunged by 413.02% to -$54.9 million in 2023, then jumped by 107.95% to $4.4 million in 2024, then jumped by 158.91% to $11.3 million in 2025, then soared by 31.41% to $14.9 million in 2026.
  • Per Business Quant, the three latest PVLA Operating Expenses figures stand at $14.9 million (Q1 2026), $11.3 million (Q4 2025), and $10.2 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Palvella Therapeutics 1.47 Bn 1.21 Bn - 14.86 Mn

Historic Data

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DateValue
Mar 31, 2026 14.86 Mn
Dec 31, 2025 11.30 Mn
Sep 30, 2025 10.18 Mn
Jun 30, 2025 9.25 Mn
Mar 31, 2025 7.87 Mn
Dec 31, 2024 4.37 Mn
Sep 30, 2024 5.06 Mn
Jun 30, 2024 2.91 Mn
Mar 31, 2024 1.76 Mn
Dec 31, 2023 -54.90 Mn
Sep 30, 2023 31.33 Mn
Jun 30, 2023 17.99 Mn
Mar 31, 2023 17.45 Mn
Sep 30, 2022 17.54 Mn
Jun 30, 2022 16.03 Mn
Mar 31, 2022 18.45 Mn
Dec 31, 2021 19.44 Mn
Sep 30, 2021 23.07 Mn
Jun 30, 2021 20.05 Mn
Mar 31, 2021 20.69 Mn
Dec 31, 2020 14.29 Mn
Sep 30, 2020 15.94 Mn
Jun 30, 2020 15.90 Mn
Mar 31, 2020 17.12 Mn
Dec 31, 2019 18.60 Mn
Sep 30, 2019 18.05 Mn
Jun 30, 2019 17.56 Mn
Mar 31, 2019 19.23 Mn
Dec 31, 2018 17.56 Mn
Sep 30, 2018 16.15 Mn
Jun 30, 2018 13.93 Mn
Mar 31, 2018 12.29 Mn
Dec 31, 2017 11.66 Mn
Sep 30, 2017 9.11 Mn
Jun 30, 2017 9.74 Mn
Mar 31, 2017 9.35 Mn
Dec 31, 2016 9.13 Mn
Sep 30, 2016 6.96 Mn
Jun 30, 2016 6.87 Mn
Mar 31, 2016 5.63 Mn
Dec 31, 2015 4.70 Mn
Sep 30, 2015 4.29 Mn
Jun 30, 2015 3.69 Mn
Mar 31, 2015 3.92 Mn
Sep 30, 2014 1.86 Mn
Jun 30, 2014 3.47 Mn
Mar 31, 2014 2.04 Mn
Dec 31, 2013 2,198.00
Sep 30, 2013 5,762.00
Jun 30, 2013 274.00