Protagonist Therapeutics (PTGX) Return on Capital Employed (2016 - 2026)
Protagonist Therapeutics' (PTGX) quarterly Return on Capital Employed came in at 21.98% in Q1 2026, up 159.0% year-on-year from 8.48% in Q1 2025, and up 11.12% quarter-over-quarter from 24.73% in Q4 2025.
Protagonist Therapeutics (PTGX) Return on Capital Employed (2016 - 2026) Analysis & Trends
Protagonist Therapeutics has disclosed Return on Capital Employed across 11 years of filings, most recently posting 21.98% for Q1 2026.
- Return on Capital Employed for Q1 2026 came in at 21.98%, up 159.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 21.98% (up 159.0% YoY), and the FY2025 annual result was 23.92%, down 3557.0% from the prior year.
- Return on Capital Employed came in at 21.98% for Q1 2026 at Protagonist Therapeutics, up from 24.73% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 49.76% in Q1 2024 to a low of 66.29% in Q1 2023.
- The 5-year median for Return on Capital Employed is 24.73% (2025), against an average of 20.99%.
- Across the five-year window, Return on Capital Employed surged 11605 bps in 2024 and sank 7333 bps in 2025, its largest moves.
- Protagonist Therapeutics' Return on Capital Employed stood at 56.17% in 2022, then surged by 91 bps to 5.14% in 2023, then soared by 282 bps to 9.36% in 2024, then tumbled by 364 bps to 24.73% in 2025, then grew by 11 bps to 21.98% in 2026.
- The last three Return on Capital Employed figures came in at 21.98% (Q1 2026), 24.73% (Q4 2025), and 26.34% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 450.31% |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 51.73% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -107.40% |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -50.43% |
| 10 | Protagonist Therapeutics | 7.35 Bn | 7.35 Bn | - | -21.98% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -21.98% |
| Dec 31, 2025 | -24.73% |
| Sep 30, 2025 | -26.34% |
| Jun 30, 2025 | -24.50% |
| Mar 31, 2025 | -23.57% |
| Dec 31, 2024 | 9.36% |
| Sep 30, 2024 | 40.06% |
| Jun 30, 2024 | 39.51% |
| Mar 31, 2024 | 49.76% |
| Dec 31, 2023 | -5.14% |
| Sep 30, 2023 | -51.52% |
| Jun 30, 2023 | -58.00% |
| Mar 31, 2023 | -66.29% |
| Dec 31, 2022 | -56.17% |
| Sep 30, 2022 | -50.80% |
| Jun 30, 2022 | -46.14% |
| Mar 31, 2022 | -40.37% |
| Dec 31, 2021 | -39.77% |
| Sep 30, 2021 | -30.80% |
| Jun 30, 2021 | -26.45% |