As of August 29, 2026, the three largest insider holders of PTGX are Dinesh V Ph D Patel (President And Ceo, 523.48K shares), Suneel Gupta (Chief Development Officer, 267.43K shares), David Y Liu (Chief Rd Strategy Officer, 167.59K shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Dinesh V Ph D Patel | President And Ceo | 523,478 | 0 | 523,478 | 43.0% | 12 Aug, 2026 |
| 2 | Suneel Gupta | Chief Development Officer | 267,433 | 0 | 267,433 | 22.0% | 27 Nov, 2024 |
| 3 | David Y Liu | Chief Rd Strategy Officer | 167,590 | 0 | 167,590 | 13.8% | 17 Nov, 2022 |
| 4 | Arturo Md Molina | Chief Medical Officer | 84,115 | 0 | 84,115 | 6.9% | 27 Mar, 2026 |
| 5 | Harold E Selick | Director | 60,845 | 0 | 60,845 | 5.0% | 27 Mar, 2026 |
| 6 | Asif Ali | Chief Financial Officer | 59,003 | 0 | 59,003 | 4.8% | 21 Apr, 2026 |
| 7 | Donald A. Kalkofen | Chief Financial Officer | 18,521 | 0 | 18,521 | 1.5% | 17 Feb, 2022 |
| 8 | Bryan Giraudo | Director | 12,695 | 0 | 12,695 | 1.0% | 11 May, 2026 |
| 9 | William D. Waddill | Director | 7,825 | 0 | 7,825 | 0.6% | 11 Jun, 2026 |
| 10 | Lewis T Williams | Director | 7,825 | 0 | 7,825 | 0.6% | 18 Feb, 2026 |
| 11 | Sarah A O'Dowd | Director | 7,825 | 0 | 7,825 | 0.6% | 06 Jan, 2026 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 10 Aug, 2026 | Dinesh V Ph D Patel | President And Ceo | Acquired M | 65,761 | $21.58 | $1.42Mn | 589,239 | Direct |
| 10 Aug, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed S | 65,761 | $149.11 | $9.81Mn | 523,478 | Direct |
| 11 Aug, 2026 | Dinesh V Ph D Patel | President And Ceo | Acquired M | 34,239 | $21.58 | $738.88K | 557,717 | Direct |
| 11 Aug, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed S | 34,239 | $148.52 | $5.09Mn | 523,478 | Direct |
| 10 Aug, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed M | 65,761 | $0.00 | $0 | 159,239 | Direct |
| 11 Aug, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed M | 34,239 | $0.00 | $0 | 125,000 | Direct |
| 10 Jun, 2026 | William D. Waddill | Director | Acquired M | 3,000 | $11.80 | $35.40K | 10,825 | Direct |
| 10 Jun, 2026 | William D. Waddill | Director | Acquired M | 6,000 | $16.54 | $99.24K | 16,825 | Direct |
| 10 Jun, 2026 | William D. Waddill | Director | Disposed S | 9,000 | $107.68 | $969.12K | 7,825 | Direct |
| 10 Jun, 2026 | William D. Waddill | Director | Disposed M | 3,000 | $0.00 | $0 | 0 | Direct |
| 10 Jun, 2026 | William D. Waddill | Director | Disposed M | 6,000 | $0.00 | $0 | 9,000 | Direct |
| 12 May, 2026 | Dinesh V Ph D Patel | President And Ceo | Acquired M | 75,000 | $21.58 | $1.62Mn | 598,478 | Direct |
| 12 May, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed S | 75,000 | $100.12 | $7.51Mn | 523,478 | Direct |
| 12 May, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed M | 75,000 | $0.00 | $0 | 225,000 | Direct |
| 12 May, 2026 | Dinesh V Ph D Patel | President And Ceo | Acquired M | 75,000 | $21.58 | $1.62Mn | 598,478 | Direct |
| 12 May, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed S | 75,000 | $100.12 | $7.51Mn | 523,478 | Direct |
| 12 May, 2026 | Dinesh V Ph D Patel | President And Ceo | Disposed M | 75,000 | $0.00 | $0 | 225,000 | Direct |
| 07 May, 2026 | Bryan Giraudo | Director | Acquired M | 24,000 | $6.45 | $154.80K | 31,825 | Direct |
| 07 May, 2026 | Bryan Giraudo | Director | Acquired M | 12,000 | $6.98 | $83.76K | 43,825 | Direct |
| 07 May, 2026 | Bryan Giraudo | Director | Disposed S | 36,000 | $100.14 | $3.61Mn | 27,825 | Direct |