Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026)
Protagonist Therapeutics (PTGX) reported Operating Expenses of $60.0 million for Q1 2026, up 26.0% on a YoY basis from $47.6 million in Q1 2025, and up 3.85% sequentially from $57.8 million in Q4 2025.
Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026) Analysis & Trends
Protagonist Therapeutics (PTGX) has 12 years of Operating Expenses data on file, last reported at $60.0 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Expenses rose 26.0% year-over-year to $60.0 million; the trailing twelve-month figure through Mar 2026 stood at $216.5 million (up 19.91% YoY), and the FY2025 full-year result was $204.1 million, up 12.42% from the prior year.
- Operating Expenses rose to $60.0 million in Q1 2026, from $57.8 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $60.0 million in Q1 2026 to a low of $32.3 million in Q3 2022.
- A 5-year average of $44.6 million and a median of $43.9 million in 2024 frame the typical range for Operating Expenses.
- Peak annual rise in Operating Expenses reached 55.02% in 2022, while the deepest fall reached 26.94% in 2022.
- Tracing PTGX's Operating Expenses over 5 years: stood at $36.5 million in 2022, then grew by 1.19% to $37.0 million in 2023, then grew by 18.69% to $43.9 million in 2024, then surged by 31.77% to $57.8 million in 2025, then advanced by 3.85% to $60.0 million in 2026.
- Business Quant data shows PTGX's Operating Expenses at $60.0 million in Q1 2026, $57.8 million in Q4 2025, and $51.1 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | Protagonist Therapeutics | 8.88 Bn | 8.88 Bn | - | 60.02 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 60.02 Mn |
| Dec 31, 2025 | 57.79 Mn |
| Sep 30, 2025 | 51.13 Mn |
| Jun 30, 2025 | 47.59 Mn |
| Mar 31, 2025 | 47.63 Mn |
| Dec 31, 2024 | 43.86 Mn |
| Sep 30, 2024 | 46.13 Mn |
| Jun 30, 2024 | 42.96 Mn |
| Mar 31, 2024 | 48.64 Mn |
| Dec 31, 2023 | 36.95 Mn |
| Sep 30, 2023 | 38.33 Mn |
| Jun 30, 2023 | 42.35 Mn |
| Mar 31, 2023 | 36.02 Mn |
| Dec 31, 2022 | 36.52 Mn |
| Sep 30, 2022 | 32.30 Mn |
| Jun 30, 2022 | 42.30 Mn |
| Mar 31, 2022 | 46.83 Mn |
| Dec 31, 2021 | 45.63 Mn |
| Sep 30, 2021 | 44.21 Mn |
| Jun 30, 2021 | 33.15 Mn |