Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026)
Protagonist Therapeutics' Operating Expenses came in at $54.71 million for Q2 2026, up 15.0% from $47.59 million a year earlier but down 8.8% from the prior quarter.
Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Protagonist Therapeutics reported Operating Expenses of $223.65 million, up 20.8% year-over-year; for FY2025, it was $204.14 million, up 12.4% from FY2024.
- Operating Expenses carries a five-year compound annual growth rate of 17.0% (FY2020 to FY2025).
- Going back by year, Operating Expenses was $181.59 million in FY2024 (+18.2%), $153.65 million in FY2023 (-2.7%), $157.95 million in FY2022 (+3.1%) and $153.2 million in FY2021 (+64.5%).
- The five-year range for quarterly Operating Expenses is $32.3 million (Q3 2022) to $60.02 million (Q1 2026).
- Year-over-year, Operating Expenses has increased for five consecutive quarters, with growth averaging 16.4% over the last eight quarters.
- The fastest year-over-year change in Operating Expenses over five years came in Q3 2021 (growth of 111.7%), and the weakest in Q3 2022 (a decline of 26.9%).
- Business Quant data shows PTGX's Operating Expenses at $60.02 million (Q1 2026), $57.79 million (Q4 2025) and $51.13 million (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 10.12 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 10.56 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 12.80 Bn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | -6.09 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | -9.70 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 6.54 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 18.20 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 6.68 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 2.09 Bn |
| 10 | Protagonist Therapeutics | 9.21 Bn | 9.21 Bn | - | 54.71 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 54.71 Mn |
| Mar 31, 2026 | 60.02 Mn |
| Dec 31, 2025 | 57.79 Mn |
| Sep 30, 2025 | 51.13 Mn |
| Jun 30, 2025 | 47.59 Mn |
| Mar 31, 2025 | 47.63 Mn |
| Dec 31, 2024 | 43.86 Mn |
| Sep 30, 2024 | 46.13 Mn |
| Jun 30, 2024 | 42.96 Mn |
| Mar 31, 2024 | 48.64 Mn |
| Dec 31, 2023 | 36.95 Mn |
| Sep 30, 2023 | 38.33 Mn |
| Jun 30, 2023 | 42.35 Mn |
| Mar 31, 2023 | 36.02 Mn |
| Dec 31, 2022 | 36.52 Mn |
| Sep 30, 2022 | 32.30 Mn |
| Jun 30, 2022 | 42.30 Mn |
| Mar 31, 2022 | 46.83 Mn |
| Dec 31, 2021 | 45.63 Mn |
| Sep 30, 2021 | 44.21 Mn |
Protagonist Therapeutics Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-expenses&ticker=PTGX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-expenses", "ticker": "PTGX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-expenses&ticker=PTGX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();