Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026)
Protagonist Therapeutics' (PTGX) quarterly Operating Expenses came in at $60.0 million in Q1 2026, up 26.0% year-on-year from $47.6 million in Q1 2025, and up 3.85% quarter-over-quarter from $57.8 million in Q4 2025.
Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026) Analysis & Trends
Protagonist Therapeutics has disclosed Operating Expenses across 12 years of filings, most recently posting $60.0 million for Q1 2026.
- Operating Expenses for Q1 2026 came in at $60.0 million, up 26.0% year-over-year; the trailing twelve-month figure through Mar 2026 was $216.5 million (up 19.91% YoY), and the FY2025 annual result was $204.1 million, up 12.42% from the prior year.
- Operating Expenses came in at $60.0 million for Q1 2026 at Protagonist Therapeutics, up from $57.8 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $60.0 million in Q1 2026 to a low of $32.3 million in Q3 2022.
- The 5-year median for Operating Expenses is $43.9 million (2024), against an average of $44.6 million.
- Peak annual rise in Operating Expenses reached 55.02% in 2022, while the deepest fall reached 26.94% in 2022.
- Protagonist Therapeutics' Operating Expenses stood at $36.5 million in 2022, then increased by 1.19% to $37.0 million in 2023, then increased by 18.69% to $43.9 million in 2024, then soared by 31.77% to $57.8 million in 2025, then climbed by 3.85% to $60.0 million in 2026.
- The last three Operating Expenses figures came in at $60.0 million (Q1 2026), $57.8 million (Q4 2025), and $51.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | Protagonist Therapeutics | 7.35 Bn | 7.35 Bn | - | 60.02 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 60.02 Mn |
| Dec 31, 2025 | 57.79 Mn |
| Sep 30, 2025 | 51.13 Mn |
| Jun 30, 2025 | 47.59 Mn |
| Mar 31, 2025 | 47.63 Mn |
| Dec 31, 2024 | 43.86 Mn |
| Sep 30, 2024 | 46.13 Mn |
| Jun 30, 2024 | 42.96 Mn |
| Mar 31, 2024 | 48.64 Mn |
| Dec 31, 2023 | 36.95 Mn |
| Sep 30, 2023 | 38.33 Mn |
| Jun 30, 2023 | 42.35 Mn |
| Mar 31, 2023 | 36.02 Mn |
| Dec 31, 2022 | 36.52 Mn |
| Sep 30, 2022 | 32.30 Mn |
| Jun 30, 2022 | 42.30 Mn |
| Mar 31, 2022 | 46.83 Mn |
| Dec 31, 2021 | 45.63 Mn |
| Sep 30, 2021 | 44.21 Mn |
| Jun 30, 2021 | 33.15 Mn |