Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026)

Protagonist Therapeutics (PTGX) reported Operating Expenses of $60.0 million for Q1 2026, up 26.0% on a YoY basis from $47.6 million in Q1 2025, and up 3.85% sequentially from $57.8 million in Q4 2025.

Protagonist Therapeutics (PTGX) Operating Expenses (2015 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 12 years of Operating Expenses data on file, last reported at $60.0 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses rose 26.0% year-over-year to $60.0 million; the trailing twelve-month figure through Mar 2026 stood at $216.5 million (up 19.91% YoY), and the FY2025 full-year result was $204.1 million, up 12.42% from the prior year.
  • Operating Expenses rose to $60.0 million in Q1 2026, from $57.8 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $60.0 million in Q1 2026 to a low of $32.3 million in Q3 2022.
  • A 5-year average of $44.6 million and a median of $43.9 million in 2024 frame the typical range for Operating Expenses.
  • Peak annual rise in Operating Expenses reached 55.02% in 2022, while the deepest fall reached 26.94% in 2022.
  • Tracing PTGX's Operating Expenses over 5 years: stood at $36.5 million in 2022, then grew by 1.19% to $37.0 million in 2023, then grew by 18.69% to $43.9 million in 2024, then surged by 31.77% to $57.8 million in 2025, then advanced by 3.85% to $60.0 million in 2026.
  • Business Quant data shows PTGX's Operating Expenses at $60.0 million in Q1 2026, $57.8 million in Q4 2025, and $51.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Protagonist Therapeutics 8.88 Bn 8.88 Bn - 60.02 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 60.02 Mn
Dec 31, 2025 57.79 Mn
Sep 30, 2025 51.13 Mn
Jun 30, 2025 47.59 Mn
Mar 31, 2025 47.63 Mn
Dec 31, 2024 43.86 Mn
Sep 30, 2024 46.13 Mn
Jun 30, 2024 42.96 Mn
Mar 31, 2024 48.64 Mn
Dec 31, 2023 36.95 Mn
Sep 30, 2023 38.33 Mn
Jun 30, 2023 42.35 Mn
Mar 31, 2023 36.02 Mn
Dec 31, 2022 36.52 Mn
Sep 30, 2022 32.30 Mn
Jun 30, 2022 42.30 Mn
Mar 31, 2022 46.83 Mn
Dec 31, 2021 45.63 Mn
Sep 30, 2021 44.21 Mn
Jun 30, 2021 33.15 Mn