Revolution Medicines (RVMD) EBITDA (2019 - 2026)

Revolution Medicines (RVMD) recorded quarterly EBITDA of -$445.2 million in Q1 2026, down 22.06% quarter-over-quarter from -$364.8 million in Q4 2025, and down 84.92% on a YoY basis from -$3.0 billion in Q1 2025.

Revolution Medicines (RVMD) EBITDA (2019 - 2026) Analysis & Trends

Revolution Medicines' EBITDA history runs 8 years deep, the most recent figure standing at -$445.2 million for Q1 2026.

  • In Q1 2026, EBITDA fell 84.92% year-over-year to -$445.2 million; the TTM figure through Mar 2026 stood at -$1.4 billion (down 84.96% YoY), while the FY2025 annual figure was -$1.1 billion, down 88.45% from the prior year.
  • EBITDA was -$445.2 million for Q1 2026 at Revolution Medicines, down from -$364.8 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$57.9 million in Q1 2022 to a low of -$445.2 million in Q1 2026.
  • Historically, EBITDA has averaged -$175.0 million across 5 years, with a median of -$150.6 million in 2024.
  • The sharpest annual moves came in 2022 and 2023: EBITDA fell 16.62% in 2022, then plunged 159.49% in 2023.
  • A 5-year view of EBITDA shows it stood at -$61.7 million in 2022, then slumped by 159.49% to -$160.1 million in 2023, then decreased by 23.07% to -$197.1 million in 2024, then tumbled by 85.11% to -$364.8 million in 2025, then dropped by 22.06% to -$445.2 million in 2026.
  • The last three EBITDA figures came in at -$445.2 million (Q1 2026), -$364.8 million (Q4 2025), and -$303.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Revolution Medicines 32.33 Bn 32.33 Bn - -445.22 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -445.22 Mn
Dec 31, 2025 -364.77 Mn
Sep 30, 2025 -303.39 Mn
Jun 30, 2025 -264.71 Mn
Mar 31, 2025 -240.76 Mn
Dec 31, 2024 -197.06 Mn
Sep 30, 2024 -150.61 Mn
Jun 30, 2024 -156.64 Mn
Mar 31, 2024 -140.86 Mn
Dec 31, 2023 -160.12 Mn
Sep 30, 2023 -108.05 Mn
Jun 30, 2023 -108.80 Mn
Mar 31, 2023 -75.16 Mn
Dec 31, 2022 -61.71 Mn
Sep 30, 2022 -76.53 Mn
Jun 30, 2022 -62.09 Mn
Mar 31, 2022 -57.95 Mn
Dec 31, 2021 -52.91 Mn
Sep 30, 2021 -53.16 Mn
Jun 30, 2021 -44.54 Mn