Alnylam Pharmaceuticals (ALNY) EBITDA (2009 - 2026)
Alnylam Pharmaceuticals' (ALNY) quarterly EBITDA came in at $231.4 million in Q2 2026, up 1528.74% YoY from $14.2 million in Q2 2025, and down 13.85% on a QoQ basis from $268.6 million in Q1 2026.
Analysis
Alnylam Pharmaceuticals (ALNY) EBITDA (2009 - 2026) Analysis & Trends
Alnylam Pharmaceuticals (ALNY) has 18 years of EBITDA data on file, last reported at $231.4 million in Q2 2026.
- Quarterly EBITDA rose 1528.74% year-over-year to $231.4 million in Q2 2026, while the trailing twelve-month figure through Jun 2026 was $999.8 million (up 654.86% YoY) and the FY2025 annual result came in at $501.6 million, up 383.56% from the prior year.
- EBITDA fell to $231.4 million in Q2 2026, from $268.6 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of $368.0 million in Q3 2025 to a low of -$258.0 million in Q3 2022.
- A 5-year average of -$13.5 million and a median of -$60.2 million in 2024 frame the typical range for EBITDA.
- Annual changes were most pronounced in 2024 — EBITDA sank 135.96% — and 2026, when it soared 1528.74%.
- Tracing ALNY's EBITDA over 5 years: stood at -$188.6 million in 2022, then jumped by 38.28% to -$116.4 million in 2023, then climbed by 9.66% to -$105.2 million in 2024, then soared by 225.26% to $131.7 million in 2025, then jumped by 75.71% to $231.4 million in 2026.
- The last three EBITDA figures came in at $231.4 million (Q2 2026), $268.6 million (Q1 2026), and $131.7 million (Q4 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 140.22 Bn | 132.37 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 86.04 Bn | 78.05 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 63.70 Bn | 58.52 Bn | 1.37 Bn | 493.00 Mn |
| 4 | Moderna | 57.56 Bn | 52.42 Bn | 52.00 Mn | -815.00 Mn |
| 5 | Revolution Medicines | 44.05 Bn | 44.05 Bn | - | -505.13 Mn |
| 6 | BeOne Medicines | 40.16 Bn | 35.06 Bn | 1.53 Bn | 325.05 Mn |
| 7 | Alnylam Pharmaceuticals | 35.63 Bn | 32.32 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Royalty Pharma | 28.63 Bn | 27.79 Bn | - | 133.12 Mn |
| 9 | Insmed | 27.73 Bn | 26.57 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Incyte | 25.60 Bn | 21.07 Bn | 1.57 Bn | 697.90 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 231.44 Mn |
| Mar 31, 2026 | 268.64 Mn |
| Dec 31, 2025 | 131.72 Mn |
| Sep 30, 2025 | 367.98 Mn |
| Jun 30, 2025 | -16.20 Mn |
| Mar 31, 2025 | 18.08 Mn |
| Dec 31, 2024 | -105.16 Mn |
| Sep 30, 2024 | -76.91 Mn |
| Jun 30, 2024 | 48.61 Mn |
| Mar 31, 2024 | -43.44 Mn |
| Dec 31, 2023 | -116.40 Mn |
| Sep 30, 2023 | 213.87 Mn |
| Jun 30, 2023 | -229.83 Mn |
| Mar 31, 2023 | -149.81 Mn |
| Dec 31, 2022 | -188.61 Mn |
| Sep 30, 2022 | -258.04 Mn |
| Jun 30, 2022 | -191.69 Mn |
| Mar 31, 2022 | -146.73 Mn |
| Dec 31, 2021 | -194.56 Mn |
| Sep 30, 2021 | -181.68 Mn |