Alnylam Pharmaceuticals (ALNY) EBITDA (2009 - 2026)
Alnylam Pharmaceuticals posted quarterly EBITDA of $201.2 million for Q1 2026, up 1046.8% year-on-year from $17.5 million in Q1 2025, and up 77.7% on a QoQ basis from $113.2 million in Q4 2025.
Alnylam Pharmaceuticals (ALNY) has 18 years of EBITDA data on file, last reported at $201.2 million in Q1 2026.
- For the quarter ending Q1 2026, EBITDA rose 1046.8% year-over-year to $201.2 million; the trailing twelve-month figure through Mar 2026 stood at $515.0 million (up 313.68% YoY), and the FY2025 full-year result was $328.2 million, up 213.44% from the prior year.
- EBITDA for Q1 2026 stood at $201.2 million, up from $113.2 million in the prior quarter.
- Across five years, EBITDA topped out at $259.3 million in Q3 2025 and bottomed at -$407.5 million in Q3 2022.
- The 5-year median for EBITDA is -$93.5 million (2024), against an average of -$79.8 million.
- The widest annual swing landed in 2024, when EBITDA slumped 166.73%; it then surged 1046.8% in 2026.
- A 5-year view of EBITDA shows it stood at -$208.4 million in 2022, then surged by 38.13% to -$128.9 million in 2023, then grew by 27.5% to -$93.5 million in 2024, then jumped by 221.15% to $113.2 million in 2025, then soared by 77.7% to $201.2 million in 2026.
- The last three EBITDA figures came in at $201.2 million (Q1 2026), $113.2 million (Q4 2025), and $259.3 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 661.60 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 201.19 Mn |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | -445.22 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 201.19 Mn |
| Dec 31, 2025 | 113.22 Mn |
| Sep 30, 2025 | 259.26 Mn |
| Jun 30, 2025 | -58.71 Mn |
| Mar 31, 2025 | -21.25 Mn |
| Dec 31, 2024 | -93.46 Mn |
| Sep 30, 2024 | -101.76 Mn |
| Jun 30, 2024 | -24.54 Mn |
| Mar 31, 2024 | -69.55 Mn |
| Dec 31, 2023 | -128.91 Mn |
| Sep 30, 2023 | 152.49 Mn |
| Jun 30, 2023 | -273.98 Mn |
| Mar 31, 2023 | -168.57 Mn |
| Dec 31, 2022 | -208.36 Mn |
| Sep 30, 2022 | -407.48 Mn |
| Jun 30, 2022 | -281.56 Mn |
| Mar 31, 2022 | -245.15 Mn |
| Dec 31, 2021 | -257.49 Mn |
| Sep 30, 2021 | -202.66 Mn |
| Jun 30, 2021 | -188.92 Mn |
| Mar 31, 2021 | -193.39 Mn |
| Dec 31, 2020 | -249.97 Mn |
| Sep 30, 2020 | -257.27 Mn |
| Jun 30, 2020 | -180.38 Mn |
| Mar 31, 2020 | -177.76 Mn |
| Dec 31, 2019 | -278.33 Mn |
| Sep 30, 2019 | -207.08 Mn |
| Jun 30, 2019 | -222.46 Mn |
| Mar 31, 2019 | -181.56 Mn |
| Dec 31, 2018 | -211.26 Mn |
| Sep 30, 2018 | -244.87 Mn |
| Jun 30, 2018 | -162.51 Mn |
| Mar 31, 2018 | -141.63 Mn |
| Dec 31, 2017 | -142.92 Mn |
| Sep 30, 2017 | -122.72 Mn |
| Jun 30, 2017 | -118.55 Mn |
| Mar 31, 2017 | -107.68 Mn |
| Dec 31, 2016 | -118.60 Mn |
| Sep 30, 2016 | -103.55 Mn |
| Jun 30, 2016 | -109.41 Mn |
| Mar 31, 2016 | -116.35 Mn |
| Dec 31, 2015 | -79.13 Mn |
| Sep 30, 2015 | -102.77 Mn |
| Jun 30, 2015 | -105.41 Mn |
| Mar 31, 2015 | -47.16 Mn |
| Dec 31, 2014 | 12.19 Mn |
| Sep 30, 2014 | -50.79 Mn |
| Jun 30, 2014 | -47.12 Mn |
| Mar 31, 2014 | -245.63 Mn |
| Dec 31, 2013 | -39.81 Mn |
| Sep 30, 2013 | -30.65 Mn |
| Jun 30, 2013 | -10.86 Mn |
| Mar 31, 2013 | -3.85 Mn |
| Dec 31, 2012 | -46.63 Mn |
| Sep 30, 2012 | -19.33 Mn |
| Jun 30, 2012 | -12.98 Mn |
| Mar 31, 2012 | -11.24 Mn |
| Dec 31, 2011 | -14.32 Mn |
| Sep 30, 2011 | -13.14 Mn |
| Jun 30, 2011 | -14.05 Mn |
| Mar 31, 2011 | -17.02 Mn |
| Dec 31, 2010 | -7.50 Mn |
| Sep 30, 2010 | -9.63 Mn |
| Jun 30, 2010 | -14.17 Mn |
| Mar 31, 2010 | -12.22 Mn |
| Dec 31, 2009 | -8.96 Mn |
| Sep 30, 2009 | -8.94 Mn |
| Jun 30, 2009 | -21.70 Mn |