Insmed (INSM) EBITDA (2010 - 2026)

Insmed (INSM) recorded quarterly EBITDA of -$165.0 million in Q1 2026, up 49.85% quarter-over-quarter from -$329.0 million in Q4 2025, and up 35.34% on a YoY basis from -$121.9 million in Q1 2025.

Insmed (INSM) EBITDA (2010 - 2026) Analysis & Trends

Insmed's EBITDA history runs 17 years deep, the most recent figure standing at -$165.0 million for Q1 2026.

  • In Q1 2026, EBITDA rose 35.34% year-over-year to -$165.0 million; the TTM figure through Mar 2026 stood at -$1.2 billion (down 16.82% YoY), while the FY2025 annual figure was -$1.3 billion, down 39.08% from the prior year.
  • EBITDA was -$165.0 million for Q1 2026 at Insmed, up from -$329.0 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$95.8 million in Q1 2022 to a low of -$369.8 million in Q3 2025.
  • Historically, EBITDA has averaged -$211.0 million across 5 years, with a median of -$184.7 million in 2023.
  • The sharpest annual moves came in 2023 and 2026: EBITDA plunged 156.52% in 2023, then soared 35.34% in 2026.
  • A 5-year view of EBITDA shows it stood at -$158.0 million in 2022, then declined by 16.93% to -$184.7 million in 2023, then declined by 29.05% to -$238.4 million in 2024, then sank by 38.02% to -$329.0 million in 2025, then jumped by 49.85% to -$165.0 million in 2026.
  • The last three EBITDA figures came in at -$165.0 million (Q1 2026), -$329.0 million (Q4 2025), and -$369.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 788,338.31 Bn 788,338.28 Bn - -
2 Belite Bio 56,560.00 Bn 56,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,329.30 Bn 17,329.30 Bn - -13.63 Mn
4 Legend Biotech 3,341.00 Bn 3,340.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,727.91 Bn 1,727.91 Bn - -14.44 Mn
6 Evaxion A 1,536.68 Bn 1,536.67 Bn - -3.82 Mn
7 Psyence Biomedical 238.34 Bn 238.33 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.42 Bn 106.17 Bn 2.59 Bn 1.14 Bn
9 Abivax 95.45 Bn 95.45 Bn - -65.83 Mn
10 Insmed 21.32 Bn 20.09 Bn 258.54 Mn -165.02 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -165.02 Mn
Dec 31, 2025 -329.02 Mn
Sep 30, 2025 -369.76 Mn
Jun 30, 2025 -319.05 Mn
Mar 31, 2025 -255.20 Mn
Dec 31, 2024 -238.38 Mn
Sep 30, 2024 -217.15 Mn
Jun 30, 2024 -301.80 Mn
Mar 31, 2024 -157.98 Mn
Dec 31, 2023 -184.73 Mn
Sep 30, 2023 -159.76 Mn
Jun 30, 2023 -247.14 Mn
Mar 31, 2023 -159.44 Mn
Dec 31, 2022 -157.98 Mn
Sep 30, 2022 -131.60 Mn
Jun 30, 2022 -96.34 Mn
Mar 31, 2022 -95.82 Mn
Dec 31, 2021 -112.11 Mn
Sep 30, 2021 -113.04 Mn
Jun 30, 2021 -116.99 Mn