Insmed (INSM) EBITDA (2010 - 2026)

Insmed's (INSM) quarterly EBITDA came in at -$153.3 million in Q1 2026, up 38.21% year-on-year from -$110.9 million in Q1 2025, and up 52.05% quarter-over-quarter from -$319.7 million in Q4 2025.

Insmed (INSM) EBITDA (2010 - 2026) Analysis & Trends

Insmed's EBITDA history runs 17 years deep, the most recent figure standing at -$153.3 million for Q1 2026.

  • On a quarterly basis, EBITDA rose 38.21% year-over-year to -$153.3 million in Q1 2026; TTM through Mar 2026 was -$1.2 billion, a 17.44% decrease from a year earlier, with the FY2025 full-year figure at -$1.2 billion, down 41.96% from the prior year.
  • EBITDA rose to -$153.3 million in Q1 2026 per INSM's latest filing, from -$319.7 million in the prior quarter.
  • Across five years, EBITDA topped out at -$88.3 million in Q2 2022 and bottomed at -$366.0 million in Q3 2025.
  • The 5-year median for EBITDA is -$178.3 million (2023), against an average of -$202.7 million.
  • Across the five-year window, EBITDA slumped 166.69% in 2023 and surged 38.21% in 2026, its largest moves.
  • Year by year, EBITDA stood at -$151.5 million in 2022, then slipped by 17.69% to -$178.3 million in 2023, then slipped by 29.25% to -$230.4 million in 2024, then slumped by 38.77% to -$319.7 million in 2025, then surged by 52.05% to -$153.3 million in 2026.
  • Per Business Quant, the three latest INSM EBITDA figures stand at -$153.3 million (Q1 2026), -$319.7 million (Q4 2025), and -$366.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Insmed 23.02 Bn 21.80 Bn 258.54 Mn -153.32 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -153.32 Mn
Dec 31, 2025 -319.75 Mn
Sep 30, 2025 -366.01 Mn
Jun 30, 2025 -312.88 Mn
Mar 31, 2025 -248.14 Mn
Dec 31, 2024 -230.41 Mn
Sep 30, 2024 -213.43 Mn
Jun 30, 2024 -288.90 Mn
Mar 31, 2024 -145.51 Mn
Dec 31, 2023 -178.27 Mn
Sep 30, 2023 -147.67 Mn
Jun 30, 2023 -235.53 Mn
Mar 31, 2023 -148.16 Mn
Dec 31, 2022 -151.48 Mn
Sep 30, 2022 -127.70 Mn
Jun 30, 2022 -88.32 Mn
Mar 31, 2022 -89.83 Mn
Dec 31, 2021 -99.08 Mn
Sep 30, 2021 -103.62 Mn
Jun 30, 2021 -88.57 Mn