Insmed (INSM) EBITDA (2010 - 2026)
Insmed (INSM) recorded quarterly EBITDA of -$165.0 million in Q1 2026, up 49.85% quarter-over-quarter from -$329.0 million in Q4 2025, and up 35.34% on a YoY basis from -$121.9 million in Q1 2025.
Insmed (INSM) EBITDA (2010 - 2026) Analysis & Trends
Insmed's EBITDA history runs 17 years deep, the most recent figure standing at -$165.0 million for Q1 2026.
- In Q1 2026, EBITDA rose 35.34% year-over-year to -$165.0 million; the TTM figure through Mar 2026 stood at -$1.2 billion (down 16.82% YoY), while the FY2025 annual figure was -$1.3 billion, down 39.08% from the prior year.
- EBITDA was -$165.0 million for Q1 2026 at Insmed, up from -$329.0 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$95.8 million in Q1 2022 to a low of -$369.8 million in Q3 2025.
- Historically, EBITDA has averaged -$211.0 million across 5 years, with a median of -$184.7 million in 2023.
- The sharpest annual moves came in 2023 and 2026: EBITDA plunged 156.52% in 2023, then soared 35.34% in 2026.
- A 5-year view of EBITDA shows it stood at -$158.0 million in 2022, then declined by 16.93% to -$184.7 million in 2023, then declined by 29.05% to -$238.4 million in 2024, then sank by 38.02% to -$329.0 million in 2025, then jumped by 49.85% to -$165.0 million in 2026.
- The last three EBITDA figures came in at -$165.0 million (Q1 2026), -$329.0 million (Q4 2025), and -$369.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 788,338.31 Bn | 788,338.28 Bn | - | - |
| 2 | Belite Bio | 56,560.00 Bn | 56,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,329.30 Bn | 17,329.30 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,341.00 Bn | 3,340.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,727.91 Bn | 1,727.91 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,536.68 Bn | 1,536.67 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 238.34 Bn | 238.33 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.42 Bn | 106.17 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 95.45 Bn | 95.45 Bn | - | -65.83 Mn |
| 10 | Insmed | 21.32 Bn | 20.09 Bn | 258.54 Mn | -165.02 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -165.02 Mn |
| Dec 31, 2025 | -329.02 Mn |
| Sep 30, 2025 | -369.76 Mn |
| Jun 30, 2025 | -319.05 Mn |
| Mar 31, 2025 | -255.20 Mn |
| Dec 31, 2024 | -238.38 Mn |
| Sep 30, 2024 | -217.15 Mn |
| Jun 30, 2024 | -301.80 Mn |
| Mar 31, 2024 | -157.98 Mn |
| Dec 31, 2023 | -184.73 Mn |
| Sep 30, 2023 | -159.76 Mn |
| Jun 30, 2023 | -247.14 Mn |
| Mar 31, 2023 | -159.44 Mn |
| Dec 31, 2022 | -157.98 Mn |
| Sep 30, 2022 | -131.60 Mn |
| Jun 30, 2022 | -96.34 Mn |
| Mar 31, 2022 | -95.82 Mn |
| Dec 31, 2021 | -112.11 Mn |
| Sep 30, 2021 | -113.04 Mn |
| Jun 30, 2021 | -116.99 Mn |