Praxis Precision Medicines (PRAX) Return on Sales (2023 - 2025)

Praxis Precision Medicines' Return on Sales history runs 3 years deep, the most recent figure standing at 0.39% for Q3 2025.

• In Q3 2025, Return on Sales rose 149.0% year-over-year to 0.39%; the TTM figure through Sep 2025 stood at 0.39% (up 63.0% YoY), while the FY2024 annual figure was 0.23%, up 28.0% from the prior year.
• Return on Sales was 0.39% for Q3 2025 at Praxis Precision Medicines, down from 0.35% in the prior quarter.
• In the past five years, Return on Sales ranged from a high of 0.09% in Q4 2024 to a low of 1.88% in Q3 2024.
• Historically, Return on Sales has averaged 0.65% across 3 years, with a median of 0.54% in 2023.
• The sharpest annual moves came in 2024 and 2025: Return on Sales tumbled 134 bps in 2024, then jumped 149 bps in 2025.
• A 3-year view of Return on Sales shows it stood at 0.54% in 2023, then surged by 84 bps to 0.09% in 2024, then tumbled by 358 bps to 0.39% in 2025.
• The last three Return on Sales figures came in at 0.39% (Q3 2025), 0.35% (Q2 2025), and 0.29% (Q1 2025), per Business Quant data.