Praxis Precision Medicines, Inc. (PRAX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

9,055,882Shares Outstanding

31,561,255Shares held by institutions

$9,103,844,005Value of institutional holdings

1,263.26%Institutional ownership %

0.06%Shares Changed QoQ

75No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Praxis Precision Medicines, Inc. (NASDAQ:PRAX) currently has 4 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

These investors collectively held 2.0% of the company's total shares outstanding in December 2025, down from 113.9% in September 2025.
Quarterly data indicates a -0.80% shift in institutional share volume, and the annual owner count reflects a decrease of 97.52%.
A review of institutional activity for Praxis Precision Medicines shows 2 of 4 filers increasing their positions, while 2 reduced their stake, and 0 remained unchanged.
The aggregate institutional position in Praxis Precision Medicines now stands at 450.24K shares as of December 2025, after investors decreased their holdings (down by 3.63K shares quarter on quarter which is down 21.92Mn shares year over year).
The top institutional stake in Praxis Precision Medicines as of December 31, 2025 belongs to Assenagon Asset Management S.A., which owns 408.79K shares, or 1.86% of the company.
Among the most significant buyers of Praxis Precision Medicines during December 2025 were CONGRESS ASSET MANAGEMENT CO (807), GAMMA Investing LLC (88).
Leading sellers of Praxis Precision Medicines stock in December 2025 included SG Americas Securities, LLC (3.53K), Assenagon Asset Management S.A. (992).
The top 4 institutional holders of Praxis Precision Medicines for the quarter ending December 2025 included Assenagon Asset Management S.A. (408.79K), CONGRESS ASSET MANAGEMENT CO (31.25K), SG Americas Securities, LLC (9.96K), GAMMA Investing LLC (238).

153 Institutional Holders

31,561,255 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
JANUS HENDERSON GROUP PLC	30 Sep, 2025	2,763,859	230,454	9.10%	$146,475,065.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	30 Sep, 2025	2,374,085	399,500	20.23%	$125,826,505.00
BlackRock, Inc.	30 Sep, 2025	1,801,080	210,952	13.27%	$95,457,240.00
PERCEPTIVE ADVISORS LLC	30 Sep, 2025	1,564,554	811,633	107.80%	$82,921,362.00
Point72 Asset Management, L.P.	30 Sep, 2025	1,495,986	541,911	56.80%	$79,287,258.00
VANGUARD GROUP INC	30 Sep, 2025	1,267,286	51,642	4.25%	$67,166,158.00
PRICE T ROWE ASSOCIATES INC /MD/	30 Sep, 2025	1,003,490	-469,585	-31.88%	$53,186.00
Cormorant Asset Management, LP	30 Sep, 2025	1,000,000	-625,000	-38.46%	$53,000,000.00
STATE STREET CORP	30 Sep, 2025	907,108	209,015	29.94%	$48,076,724.00
Soleus Capital Management, L.P.	30 Sep, 2025	859,166	-107,574	-11.13%	$45,535,798.00
DEERFIELD MANAGEMENT COMPANY, L.P.	30 Sep, 2025	840,851	153,920	22.41%	$44,565,103.00
BAKER BROS. ADVISORS LP	30 Sep, 2025	689,488	0	0.00%	$36,542,864.00
MORGAN STANLEY	30 Sep, 2025	643,495	-582,844	-47.53%	$34,105,272.00
GOLDMAN SACHS GROUP INC	30 Sep, 2025	593,021	367,029	162.41%	$31,430,113.00
DRIEHAUS CAPITAL MANAGEMENT LLC	30 Sep, 2025	500,551	-30,437	-5.73%	$26,529,203.00
BANK OF AMERICA CORP /DE/	30 Sep, 2025	482,861	29,458	6.50%	$25,591,633.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	457,032	5,301	1.17%	$24,226,192.00
Woodline Partners LP	30 Sep, 2025	417,669	371,717	808.92%	$22,136,457.00
Assenagon Asset Management S.A.	30 Sep, 2025	409,779	-194,519	-32.19%	$21,718,287.00
CIBC Asset Management Inc	30 Sep, 2025	388,759	0	0.00%	$20,604,227.00

1 - 20 of 153

Research Tools

Praxis Precision Medicines, Inc. (PRAX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

153 Institutional Holders

Create an account

Sign In

Reset Password

Get Pro for 60% off