Over the 90-day window ending January 10, 2026, Praxis Precision Medicines's three dominant insider ownership positions are held by TenPercentOwner Capital Management, L.P. Adage (2.06Mn shares), TenPercentOwner Lifesciences Iii, L.P. Clarus (326.29K shares), Chief Executive Officer Marcio Souza (56.10K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| Lifesciences Iii, L.P. Clarus | 326,290 | 14 May, 2021 | |
| Capital Management, L.P. Adage | 2,060,175 | 17 Oct, 2025 | |
| Bernard Ravina | Chief Medical Officer | 6,632 | 15 Feb, 2022 |
| Marcio Souza | Chief Executive Officer | 56,102 | 09 Jan, 2026 |
| Nicole Sweeny | Chief Commercial Officer | 2,575 | 13 Feb, 2023 |
| William D Young | 1,898 | 07 Jul, 2021 | |
| Timothy Edwin Kelly | Chief Financial Officer | 24,524 | 09 Jan, 2026 |
| Alex Nemiroff | General Counsel And Secretary | 20,743 | 09 Jan, 2026 |
| Dean J Mitchell | 17,251 | 25 Sep, 2025 | |
| Jill Desimone | 967 | 10 Oct, 2023 | |
| Lauren Mastrocola | Principal Accounting Officer | 10,407 | 09 Jan, 2026 |
| Gregory Norden | 188 | 07 Jul, 2021 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 07 Jan, 2026 | Marcio Souza | Common Stock | D | 405 | $292.63 | 53,502 | D | F |
| 07 Jan, 2026 | Lauren Mastrocola | Common Stock | D | 35 | $292.63 | 10,407 | D | F |
| 07 Jan, 2026 | Alex Nemiroff | Common Stock | D | 89 | $292.63 | 20,743 | D | F |
| 07 Jan, 2026 | Timothy Edwin Kelly | Common Stock | D | 139 | $292.63 | 24,524 | D | F |
| 30 Dec, 2025 | Marcio Souza | - | - | 2,600 | I | |||
| 30 Dec, 2025 | Marcio Souza | Common Stock | D | 400 | $0.00 | 2,600 | I | G |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | D | 2,145 | $192.71 | 10,442 | D | S |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | D | 11,455 | $191.96 | 12,587 | D | S |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 207 | $44.40 | 16,441 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 1,047 | $49.50 | 11,489 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 508 | $83.85 | 11,997 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 2,351 | $44.40 | 18,792 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 1,557 | $133.65 | 13,554 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 5,250 | $56.94 | 24,042 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 2,680 | $43.37 | 16,234 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 6,230 | $133.65 | 28,776 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | D | 977 | $193.23 | 29,932 | D | S |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | D | 1,714 | $190.86 | 44,248 | D | S |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 5,652 | $44.40 | 36,862 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 1,714 | $83.85 | 22,546 | D | M |