Based on data from the past 90 days ending February 07, 2026, Praxis Precision Medicines's three largest insider shareholders are TenPercentOwner Capital Management, L.P. Adage (2.06Mn shares), TenPercentOwner Lifesciences Iii, L.P. Clarus (326.29K shares), Chief Executive Officer Marcio Souza (79.49K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| Lifesciences Iii, L.P. Clarus | 326,290 | 14 May, 2021 | |
| Capital Management, L.P. Adage | 2,060,175 | 17 Oct, 2025 | |
| Bernard Ravina | Chief Medical Officer | 6,632 | 15 Feb, 2022 |
| Marcio Souza | Chief Executive Officer | 79,490 | 12 Jan, 2026 |
| Nicole Sweeny | Chief Commercial Officer | 2,575 | 13 Feb, 2023 |
| Timothy Edwin Kelly | Chief Financial Officer | 31,046 | 13 Jan, 2026 |
| Megan Sniecinski | Chief Operating Officer | 28,530 | 13 Jan, 2026 |
| William D Young | 1,898 | 07 Jul, 2021 | |
| Alex Nemiroff | General Counsel And Secretary | 25,933 | 13 Jan, 2026 |
| Dean J Mitchell | 17,251 | 25 Sep, 2025 | |
| Jill Desimone | 967 | 10 Oct, 2023 | |
| Lauren Mastrocola | Principal Accounting Officer | 13,446 | 13 Jan, 2026 |
| Gregory Norden | 188 | 07 Jul, 2021 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 12 Jan, 2026 | Megan Sniecinski | Common Stock | D | 885 | $275.74 | 28,530 | D | F |
| 12 Jan, 2026 | Lauren Mastrocola | Common Stock | D | 344 | $275.74 | 13,446 | D | F |
| 12 Jan, 2026 | Alex Nemiroff | Common Stock | D | 768 | $275.74 | 25,933 | D | F |
| 12 Jan, 2026 | Timothy Edwin Kelly | Common Stock | D | 943 | $275.74 | 31,046 | D | F |
| 10 Jan, 2026 | Marcio Souza | Common Stock | D | 4,252 | $288.45 | 76,890 | D | F |
| 10 Jan, 2026 | Megan Sniecinski | Common Stock | D | 1,087 | $288.45 | 29,415 | D | F |
| 10 Jan, 2026 | Lauren Mastrocola | Common Stock | D | 367 | $288.45 | 13,790 | D | F |
| 10 Jan, 2026 | Alex Nemiroff | Common Stock | D | 917 | $288.45 | 26,701 | D | F |
| 10 Jan, 2026 | Timothy Edwin Kelly | Common Stock | D | 1,335 | $288.45 | 31,989 | D | F |
| 08 Jan, 2026 | Marcio Souza | Common Stock | A | 27,640 | $0.00 | 81,142 | D | A |
| 08 Jan, 2026 | Megan Sniecinski | Common Stock | A | 9,625 | $0.00 | 30,502 | D | A |
| 08 Jan, 2026 | Lauren Mastrocola | Common Stock | A | 3,750 | $0.00 | 14,157 | D | A |
| 08 Jan, 2026 | Alex Nemiroff | Common Stock | A | 6,875 | $0.00 | 27,618 | D | A |
| 08 Jan, 2026 | Timothy Edwin Kelly | Common Stock | A | 8,800 | $0.00 | 33,324 | D | A |
| 07 Jan, 2026 | Marcio Souza | Common Stock | D | 405 | $292.63 | 53,502 | D | F |
| 07 Jan, 2026 | Lauren Mastrocola | Common Stock | D | 35 | $292.63 | 10,407 | D | F |
| 07 Jan, 2026 | Alex Nemiroff | Common Stock | D | 89 | $292.63 | 20,743 | D | F |
| 07 Jan, 2026 | Timothy Edwin Kelly | Common Stock | D | 139 | $292.63 | 24,524 | D | F |
| 30 Dec, 2025 | Marcio Souza | Common Stock | D | 400 | $0.00 | 2,600 | I | G |
| 30 Dec, 2025 | Marcio Souza | - | - | 2,600 | I |