Data spanning the past 90 days through December 12, 2025 reveals that Praxis Precision Medicines's three principal insider shareholders consist of TenPercentOwner Capital Management, L.P. Adage (2.06Mn shares), Chief Financial Officer Timothy Edwin Kelly (24.66K shares), General Counsel And Secretary Alex Nemiroff (20.83K shares).
| Holder | Position | Shares | Report Date |
|---|---|---|---|
| Lifesciences Iii, L.P. Clarus | 326,290 | 14 May, 2021 | |
| Capital Management, L.P. Adage | 2,060,175 | 17 Oct, 2025 | |
| Bernard Ravina | Chief Medical Officer | 6,632 | 15 Feb, 2022 |
| Marcio Souza | Chief Executive Officer | 56,907 | 19 May, 2025 |
| Nicole Sweeny | Chief Commercial Officer | 2,575 | 13 Feb, 2023 |
| William D Young | 1,898 | 07 Jul, 2021 | |
| Timothy Edwin Kelly | Chief Financial Officer | 24,663 | 21 Nov, 2025 |
| Alex Nemiroff | General Counsel And Secretary | 20,832 | 21 Nov, 2025 |
| Dean J Mitchell | 17,251 | 25 Sep, 2025 | |
| Jill Desimone | 967 | 10 Oct, 2023 | |
| Lauren Mastrocola | Principal Accounting Officer | 10,442 | 21 Nov, 2025 |
| Gregory Norden | 188 | 07 Jul, 2021 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 1,714 | $83.85 | 22,546 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 1,047 | $49.50 | 11,489 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 508 | $83.85 | 11,997 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 6,230 | $133.65 | 28,776 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 1,557 | $133.65 | 13,554 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 2,434 | $44.40 | 31,210 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 5,652 | $44.40 | 36,862 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 2,680 | $43.37 | 16,234 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | A | 9,100 | $56.94 | 45,962 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 207 | $44.40 | 16,441 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | D | 1,714 | $190.86 | 44,248 | D | S |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 2,351 | $44.40 | 18,792 | D | M |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | A | 5,250 | $56.94 | 24,042 | D | M |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | D | 13,339 | $192.53 | 30,909 | D | S |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | D | 11,455 | $191.96 | 12,587 | D | S |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | D | 977 | $193.23 | 29,932 | D | S |
| 20 Nov, 2025 | Alex Nemiroff | Common Stock | D | 9,100 | $194.30 | 20,832 | D | S |
| 20 Nov, 2025 | Lauren Mastrocola | Common Stock | D | 2,145 | $192.71 | 10,442 | D | S |
| 14 Nov, 2025 | Timothy Edwin Kelly | Common Stock | A | 384 | $31.62 | 24,663 | D | A |
| 16 Oct, 2025 | Capital Management, L.P. Adage | Common Stock, $0.0001 par value per share ("Common Stock") | A | 12,600 | $90.00 | 2,361,485 | I | S |