Praxis Precision Medicines (PRAX) Return on Capital Employed (2020 - 2026)

Praxis Precision Medicines' (PRAX) quarterly Return on Capital Employed came in at 31.1% in Q1 2026, up 2168.0% year-on-year from 1.37% in Q1 2025, and up 42.08% quarter-over-quarter from 53.71% in Q4 2025.

Praxis Precision Medicines (PRAX) Return on Capital Employed (2020 - 2026) Analysis & Trends

Praxis Precision Medicines' Return on Capital Employed history runs 7 years deep, the most recent figure standing at 31.1% for Q1 2026.

  • On a quarterly basis, Return on Capital Employed rose 2168.0% year-over-year to 31.1% in Q1 2026; TTM through Mar 2026 was 31.1%, a 2168.0% increase from a year earlier, with the FY2025 full-year figure at 50.13%, up 3059.0% from the prior year.
  • Return on Capital Employed grew to 31.1% in Q1 2026 per PRAX's latest filing, from 53.71% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 31.1% in Q1 2026 and bottomed at 239.76% in Q1 2023.
  • The 5-year median for Return on Capital Employed is 86.56% (2024), against an average of 108.61%.
  • Across the five-year window, Return on Capital Employed plunged 17258 bps in 2022 and jumped 15320 bps in 2024, its largest moves.
  • Year by year, Return on Capital Employed stood at 234.52% in 2022, then surged by 34 bps to 154.89% in 2023, then surged by 69 bps to 48.57% in 2024, then dropped by 11 bps to 53.71% in 2025, then surged by 42 bps to 31.1% in 2026.
  • Per Business Quant, the three latest PRAX Return on Capital Employed figures stand at 31.1% (Q1 2026), 53.71% (Q4 2025), and 78.85% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Praxis Precision Medicines 8.98 Bn 8.20 Bn - -31.10%

Historic Data

Download Data
DateValue
Mar 31, 2026 -31.10%
Dec 31, 2025 -53.71%
Sep 30, 2025 -78.85%
Jun 30, 2025 -65.10%
Mar 31, 2025 -52.79%
Dec 31, 2024 -48.57%
Sep 30, 2024 -41.44%
Jun 30, 2024 -40.81%
Mar 31, 2024 -86.56%
Dec 31, 2023 -154.89%
Sep 30, 2023 -135.52%
Jun 30, 2023 -173.53%
Mar 31, 2023 -239.76%
Dec 31, 2022 -234.52%
Sep 30, 2022 -179.05%
Jun 30, 2022 -135.73%
Mar 31, 2022 -94.50%
Dec 31, 2021 -61.94%
Sep 30, 2021 -42.77%
Jun 30, 2021 -35.21%