Growth Metrics

Praxis Precision Medicines (PRAX) Free Cash Flow (2019 - 2026)

Praxis Precision Medicines' quarterly Free Cash Flow came in at -$86.2 million in Q1 2026, down 62.32% year-on-year from -$228.7 million in Q1 2025, and down 12.88% quarter-over-quarter from -$76.3 million in Q4 2025.

Praxis Precision Medicines has reported Free Cash Flow for 8 years, with the latest figure at -$86.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Free Cash Flow fell 62.32% year-over-year to -$86.2 million; the trailing twelve-month figure through Mar 2026 stood at -$282.2 million (down 72.1% YoY), and the FY2025 full-year result was -$249.1 million, down 89.08% from the prior year.
  • Free Cash Flow for Q1 2026 stood at -$86.2 million, down from -$76.3 million in the prior quarter.
  • The five-year high for Free Cash Flow was -$20.9 million in Q1 2024, with the low at -$86.2 million in Q1 2026.
  • Average Free Cash Flow over 5 years is -$44.9 million, with a median of -$44.5 million recorded in 2022.
  • Year-over-year, Free Cash Flow jumped 47.74% in 2023 and tumbled 154.47% in 2025.
  • Tracing PRAX's Free Cash Flow over 5 years: stood at -$29.2 million in 2022, then climbed by 18.42% to -$23.9 million in 2023, then slumped by 135.2% to -$56.1 million in 2024, then plunged by 36.0% to -$76.3 million in 2025, then decreased by 12.88% to -$86.2 million in 2026.
  • The last three Free Cash Flow figures came in at -$86.2 million (Q1 2026), -$76.3 million (Q4 2025), and -$65.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -1.67 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 48.67 Mn
10 Praxis Precision Medicines 10.11 Bn 9.32 Bn - -86.15 Mn

Historic Data

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DateValue
Mar 31, 2026 -86.15 Mn
Mar 31, 2026 -86.15 Mn
Dec 31, 2025 -76.33 Mn
Dec 31, 2025 -76.33 Mn
Sep 30, 2025 -65.06 Mn
Sep 30, 2025 -65.06 Mn
Jun 30, 2025 -54.67 Mn
Jun 30, 2025 -54.67 Mn
Mar 31, 2025 -53.07 Mn
Mar 31, 2025 -53.07 Mn
Dec 31, 2024 -56.12 Mn
Dec 31, 2024 -56.12 Mn
Sep 30, 2024 -27.50 Mn
Sep 30, 2024 -27.50 Mn
Jun 30, 2024 -27.28 Mn
Jun 30, 2024 -27.28 Mn
Mar 31, 2024 -20.86 Mn
Mar 31, 2024 -20.86 Mn
Dec 31, 2023 -23.86 Mn
Dec 31, 2023 -23.86 Mn
Sep 30, 2023 -23.27 Mn
Sep 30, 2023 -23.27 Mn
Jun 30, 2023 -31.21 Mn
Jun 30, 2023 -31.21 Mn
Mar 31, 2023 -32.85 Mn
Mar 31, 2023 -32.85 Mn
Dec 31, 2022 -29.25 Mn
Dec 31, 2022 -29.25 Mn
Sep 30, 2022 -44.52 Mn
Sep 30, 2022 -44.52 Mn
Jun 30, 2022 -57.32 Mn
Jun 30, 2022 -57.32 Mn
Mar 31, 2022 -54.40 Mn
Mar 31, 2022 -54.40 Mn
Dec 31, 2021 -45.39 Mn
Dec 31, 2021 -45.39 Mn
Sep 30, 2021 -24.40 Mn
Sep 30, 2021 -24.40 Mn
Jun 30, 2021 -30.09 Mn
Jun 30, 2021 -30.09 Mn
Mar 31, 2021 -25.73 Mn
Mar 31, 2021 -25.73 Mn
Dec 31, 2020 -20.23 Mn
Dec 31, 2020 -20.23 Mn
Sep 30, 2020 -13.88 Mn
Sep 30, 2020 -13.88 Mn
Jun 30, 2020 -9.94 Mn
Jun 30, 2020 -9.94 Mn
Mar 31, 2020 -8.57 Mn
Mar 31, 2020 -8.57 Mn
Dec 31, 2019 -9.85 Mn
Dec 31, 2019 -9.85 Mn