Praxis Precision Medicines (PRAX) Enterprise Value (2019 - 2026)

Praxis Precision Medicines' (PRAX) quarterly Enterprise Value came in at -$786.9 million in Q1 2026, down 139.9% year-on-year from $2.0 billion in Q1 2025, and down 31.29% quarter-over-quarter from -$599.3 million in Q4 2025.

Praxis Precision Medicines (PRAX) Enterprise Value (2019 - 2026) Analysis & Trends

Praxis Precision Medicines' Enterprise Value history runs 8 years deep, the most recent figure standing at -$786.9 million for Q1 2026.

  • On a quarterly basis, Enterprise Value fell 139.9% year-over-year to -$786.9 million in Q1 2026; TTM through Mar 2026 was -$786.9 million, a 139.9% decrease from a year earlier, with the FY2025 full-year figure at -$599.3 million, down 52.67% from the prior year.
  • Enterprise Value slipped to -$786.9 million in Q1 2026 per PRAX's latest filing, from -$599.3 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$56.0 million in Q2 2022 and bottomed at -$786.9 million in Q1 2026.
  • The 5-year median for Enterprise Value is -$207.4 million (2024), against an average of -$249.2 million.
  • Across the five-year window, Enterprise Value soared 68.14% in 2022 and plunged 382.86% in 2024, its largest moves.
  • Year by year, Enterprise Value stood at -$61.6 million in 2022, then sank by 31.95% to -$81.3 million in 2023, then plunged by 382.86% to -$392.6 million in 2024, then plunged by 52.67% to -$599.3 million in 2025, then tumbled by 31.29% to -$786.9 million in 2026.
  • Per Business Quant, the three latest PRAX Enterprise Value figures stand at -$786.9 million (Q1 2026), -$599.3 million (Q4 2025), and -$267.2 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Praxis Precision Medicines 8.98 Bn 8.20 Bn - -786.87 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -786.87 Mn
Dec 31, 2025 -599.33 Mn
Sep 30, 2025 -267.16 Mn
Jun 30, 2025 -301.28 Mn
Mar 31, 2025 -327.99 Mn
Dec 31, 2024 -392.57 Mn
Sep 30, 2024 -357.03 Mn
Jun 30, 2024 -351.88 Mn
Mar 31, 2024 -207.42 Mn
Dec 31, 2023 -81.30 Mn
Sep 30, 2023 -101.09 Mn
Jun 30, 2023 -124.30 Mn
Mar 31, 2023 -80.84 Mn
Dec 31, 2022 -61.62 Mn
Sep 30, 2022 -62.44 Mn
Jun 30, 2022 -56.04 Mn
Mar 31, 2022 -77.85 Mn
Dec 31, 2021 -138.70 Mn
Sep 30, 2021 -165.68 Mn
Jun 30, 2021 -175.88 Mn