Praxis Precision Medicines (PRAX) Enterprise Value (2019 - 2026)

Praxis Precision Medicines (PRAX) recorded quarterly Enterprise Value of -$786.9 million in Q1 2026, down 31.29% quarter-over-quarter from -$599.3 million in Q4 2025, and down 139.9% on a YoY basis from $2.0 billion in Q1 2025.

Praxis Precision Medicines (PRAX) Enterprise Value (2019 - 2026) Analysis & Trends

Praxis Precision Medicines' Enterprise Value history runs 8 years deep, the most recent figure standing at -$786.9 million for Q1 2026.

  • In Q1 2026, Enterprise Value fell 139.9% year-over-year to -$786.9 million; the TTM figure through Mar 2026 stood at -$786.9 million (down 139.9% YoY), while the FY2025 annual figure was -$599.3 million, down 52.67% from the prior year.
  • Enterprise Value was -$786.9 million for Q1 2026 at Praxis Precision Medicines, down from -$599.3 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$56.0 million in Q2 2022 to a low of -$786.9 million in Q1 2026.
  • Historically, Enterprise Value has averaged -$249.2 million across 5 years, with a median of -$207.4 million in 2024.
  • The sharpest annual moves came in 2022 and 2024: Enterprise Value jumped 68.14% in 2022, then plunged 382.86% in 2024.
  • A 5-year view of Enterprise Value shows it stood at -$61.6 million in 2022, then tumbled by 31.95% to -$81.3 million in 2023, then slumped by 382.86% to -$392.6 million in 2024, then slumped by 52.67% to -$599.3 million in 2025, then sank by 31.29% to -$786.9 million in 2026.
  • The last three Enterprise Value figures came in at -$786.9 million (Q1 2026), -$599.3 million (Q4 2025), and -$267.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Praxis Precision Medicines 200.22 Mn -586.65 Mn - -786.87 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -786.87 Mn
Dec 31, 2025 -599.33 Mn
Sep 30, 2025 -267.16 Mn
Jun 30, 2025 -301.28 Mn
Mar 31, 2025 -327.99 Mn
Dec 31, 2024 -392.57 Mn
Sep 30, 2024 -357.03 Mn
Jun 30, 2024 -351.88 Mn
Mar 31, 2024 -207.42 Mn
Dec 31, 2023 -81.30 Mn
Sep 30, 2023 -101.09 Mn
Jun 30, 2023 -124.30 Mn
Mar 31, 2023 -80.84 Mn
Dec 31, 2022 -61.62 Mn
Sep 30, 2022 -62.44 Mn
Jun 30, 2022 -56.04 Mn
Mar 31, 2022 -77.85 Mn
Dec 31, 2021 -138.70 Mn
Sep 30, 2021 -165.68 Mn
Jun 30, 2021 -175.88 Mn