Praxis Precision Medicines PRAX
NASDAQ PRAX
$371.47 +3.45 (+0.94%)
As of: Aug 26, 2026 · 9:41 AM EDT

Praxis Precision Medicines (PRAX) Enterprise Value (2019 - 2026)

Praxis Precision Medicines (PRAX) posted quarterly Enterprise Value of -$786.9 million for Q1 2026, down 139.9% year-over-year from $2.0 billion in Q1 2025, and down 31.29% quarter-over-quarter from -$599.3 million in Q4 2025.

Praxis Precision Medicines (PRAX) Enterprise Value (2019 - 2026) Analysis & Trends

Praxis Precision Medicines' Enterprise Value history runs 8 years deep, the most recent figure standing at -$786.9 million for Q1 2026.

  • In Q1 2026, Enterprise Value fell 139.9% year-over-year to -$786.9 million; the TTM figure through Mar 2026 stood at -$786.9 million (down 139.9% YoY), while the FY2025 annual figure was -$599.3 million, down 52.67% from the prior year.
  • Enterprise Value for Q1 2026 stood at -$786.9 million, down from -$599.3 million in the prior quarter.
  • The five-year high for Enterprise Value was -$56.0 million in Q2 2022, with the low at -$786.9 million in Q1 2026.
  • The 5-year median for Enterprise Value is -$207.4 million (2024), against an average of -$249.2 million.
  • The sharpest annual moves came in 2022 and 2024: Enterprise Value soared 68.14% in 2022, then tumbled 382.86% in 2024.
  • Praxis Precision Medicines' Enterprise Value stood at -$61.6 million in 2022, then slumped by 31.95% to -$81.3 million in 2023, then sank by 382.86% to -$392.6 million in 2024, then sank by 52.67% to -$599.3 million in 2025, then plunged by 31.29% to -$786.9 million in 2026.
  • Business Quant data shows PRAX's Enterprise Value at -$786.9 million in Q1 2026, -$599.3 million in Q4 2025, and -$267.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 139.72 Bn 131.87 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 85.07 Bn 77.08 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 64.59 Bn 59.41 Bn 1.37 Bn -5.18 Bn
4 Moderna 59.76 Bn 54.62 Bn 52.00 Mn -5.14 Bn
5 BeOne Medicines 41.86 Bn 36.77 Bn 1.53 Bn -5.10 Bn
6 Alnylam Pharmaceuticals 31.83 Bn 28.52 Bn 992.69 Mn -3.31 Bn
7 Royalty Pharma 27.47 Bn 26.64 Bn - 2.12 Bn
8 BioNTech SE 27.25 Bn 8.85 Bn 668.28 Mn -18.39 Bn
9 Insmed 26.73 Bn 25.57 Bn 358.27 Mn -1.16 Bn
10 Praxis Precision Medicines 10.71 Bn 9.95 Bn - -758.55 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -758.55 Mn
Mar 31, 2026 -786.87 Mn
Dec 31, 2025 -599.33 Mn
Sep 30, 2025 -267.16 Mn
Jun 30, 2025 -301.28 Mn
Mar 31, 2025 -327.99 Mn
Dec 31, 2024 -392.57 Mn
Sep 30, 2024 -357.03 Mn
Jun 30, 2024 -351.88 Mn
Mar 31, 2024 -207.42 Mn
Dec 31, 2023 -81.30 Mn
Sep 30, 2023 -101.09 Mn
Jun 30, 2023 -124.30 Mn
Mar 31, 2023 -80.84 Mn
Dec 31, 2022 -61.62 Mn
Sep 30, 2022 -62.44 Mn
Jun 30, 2022 -56.04 Mn
Mar 31, 2022 -77.85 Mn
Dec 31, 2021 -138.70 Mn
Sep 30, 2021 -165.68 Mn