Praxis Precision Medicines (PRAX) Change in Cash (2019 - 2026)
Praxis Precision Medicines (PRAX) posted Change in Cash of -$62.0 million for Q2 2026, down 134.63% on a QoQ basis from $179.0 million in Q1 2026, and down 660.4% year-over-year from $11.1 million in Q2 2025.
Praxis Precision Medicines (PRAX) Change in Cash (2019 - 2026) Analysis & Trends
Praxis Precision Medicines has reported Change in Cash for 8 years, with the latest figure at -$62.0 million in Q2 2026.
- On a quarterly basis, Change in Cash fell 660.4% year-over-year to -$62.0 million in Q2 2026; TTM through Jun 2026 was $316.9 million, a 2482.55% increase from a year earlier, with the FY2025 full-year figure at $142.0 million, up 5.88% from the prior year.
- Change in Cash was -$62.0 million for Q2 2026 at Praxis Precision Medicines, down from $179.0 million in the prior quarter.
- The five-year high for Change in Cash was $207.8 million in Q4 2025, with the low at -$62.0 million in Q2 2026.
- Average Change in Cash over 5 years is $18.6 million, with a median of -$3.8 million recorded in 2022.
- The sharpest annual moves came in 2023 and 2026: Change in Cash sank 2298.18% in 2023, then jumped 459.41% in 2026.
- Over 5 years, Change in Cash stood at -$825000.0 in 2022, then tumbled by 2298.18% to -$19.8 million in 2023, then soared by 336.17% to $46.7 million in 2024, then jumped by 344.72% to $207.8 million in 2025, then tumbled by 129.83% to -$62.0 million in 2026.
- The last three Change in Cash figures came in at -$62.0 million (Q2 2026), $179.0 million (Q1 2026), and $207.8 million (Q4 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 212.54 Bn | 198.55 Bn | 7.24 Bn | 1.95 Bn |
| 2 | Gilead Sciences | 186.84 Bn | 183.58 Bn | 6.22 Bn | -4.45 Bn |
| 3 | Vertex Pharmaceuticals | 129.39 Bn | 121.54 Bn | 2.84 Bn | 649.20 Mn |
| 4 | Regeneron Pharmaceuticals | 82.05 Bn | 74.06 Bn | 3.93 Bn | -504.60 Mn |
| 5 | Moderna | 69.00 Bn | 63.87 Bn | 52.00 Mn | -185.00 Mn |
| 6 | Argenx Se | 61.15 Bn | 55.97 Bn | 1.37 Bn | - |
| 7 | Alnylam Pharmaceuticals | 32.67 Bn | 29.37 Bn | 992.69 Mn | -2.94 Mn |
| 8 | Biogen | 32.37 Bn | 31.08 Bn | 1.96 Bn | -2.09 Bn |
| 9 | Roivant Sciences | 28.18 Bn | 28.87 Bn | 1.16 Mn | -170.44 Mn |
| 10 | Praxis Precision Medicines | 8.34 Bn | 7.58 Bn | - | -61.99 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -61.99 Mn |
| Mar 31, 2026 | 179.00 Mn |
| Dec 31, 2025 | 207.80 Mn |
| Sep 30, 2025 | -7.89 Mn |
| Jun 30, 2025 | -8.15 Mn |
| Mar 31, 2025 | -49.81 Mn |
| Dec 31, 2024 | 46.73 Mn |
| Sep 30, 2024 | 23.50 Mn |
| Jun 30, 2024 | -6.84 Mn |
| Mar 31, 2024 | 70.68 Mn |
| Dec 31, 2023 | -19.79 Mn |
| Sep 30, 2023 | -23.22 Mn |
| Jun 30, 2023 | 43.46 Mn |
| Mar 31, 2023 | 19.22 Mn |
| Dec 31, 2022 | -825,000.00 |
| Sep 30, 2022 | 6.40 Mn |
| Jun 30, 2022 | -21.82 Mn |
| Mar 31, 2022 | -61.45 Mn |
| Dec 31, 2021 | -26.98 Mn |
| Sep 30, 2021 | -10.20 Mn |
Praxis Precision Medicines Change in Cash API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=change-in-cash&ticker=PRAX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "change-in-cash", "ticker": "PRAX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=change-in-cash&ticker=PRAX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();