Pliant Therapeutics (PLRX) Operating Expenses (2019 - 2026)

Pliant Therapeutics (PLRX) reported Operating Expenses of $21.8 million for Q1 2026, down 63.06% year-over-year from $58.9 million in Q1 2025, and down 7.66% quarter-over-quarter from $23.6 million in Q4 2025.

Pliant Therapeutics (PLRX) Operating Expenses (2019 - 2026) Analysis & Trends

Pliant Therapeutics (PLRX) has 8 years of Operating Expenses data on file, last reported at $21.8 million in Q1 2026.

  • Operating Expenses for Q1 2026 came in at $21.8 million, down 63.06% year-over-year; the trailing twelve-month figure through Mar 2026 was $119.2 million (down 49.25% YoY), and the FY2025 annual result was $156.4 million, down 31.52% from the prior year.
  • Operating Expenses eased to $21.8 million in Q1 2026 per PLRX's latest filing, from $23.6 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $62.0 million in Q3 2024 and troughed at $21.8 million in Q1 2026.
  • A 5-year average of $42.9 million and a median of $45.6 million in 2025 frame the typical range for Operating Expenses.
  • The sharpest annual moves came in 2022 and 2026: Operating Expenses surged 48.0% in 2022, then plunged 63.06% in 2026.
  • A 5-year view of Operating Expenses shows it stood at $39.4 million in 2022, then rose by 19.49% to $47.0 million in 2023, then climbed by 13.36% to $53.3 million in 2024, then tumbled by 55.78% to $23.6 million in 2025, then slipped by 7.66% to $21.8 million in 2026.
  • Business Quant data shows PLRX's Operating Expenses at $21.8 million in Q1 2026, $23.6 million in Q4 2025, and $28.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - 4.33 Mn
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - 32.68 Mn
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - 2.97 Mn
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - 15.76 Mn
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -3.82 Mn
7 Psyence Biomedical 251.43 Bn 251.42 Bn - 574,669.00
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 1.85 Bn
9 Abivax 94.37 Bn 94.37 Bn - -67.40 Mn
10 Pliant Therapeutics 71.07 Mn 71.07 Mn - 21.77 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 21.77 Mn
Dec 31, 2025 23.58 Mn
Sep 30, 2025 28.27 Mn
Jun 30, 2025 45.59 Mn
Mar 31, 2025 58.94 Mn
Dec 31, 2024 53.32 Mn
Sep 30, 2024 62.01 Mn
Jun 30, 2024 60.64 Mn
Mar 31, 2024 52.39 Mn
Dec 31, 2023 47.04 Mn
Sep 30, 2023 47.69 Mn
Jun 30, 2023 47.58 Mn
Mar 31, 2023 43.43 Mn
Dec 31, 2022 39.37 Mn
Sep 30, 2022 33.43 Mn
Jun 30, 2022 34.63 Mn
Mar 31, 2022 29.46 Mn
Dec 31, 2021 26.60 Mn
Sep 30, 2021 28.72 Mn
Jun 30, 2021 24.69 Mn