Pliant Therapeutics (PLRX) Operating Expenses (2019 - 2026)
Pliant Therapeutics (PLRX) reported Operating Expenses of $21.8 million for Q1 2026, down 63.06% year-over-year from $58.9 million in Q1 2025, and down 7.66% quarter-over-quarter from $23.6 million in Q4 2025.
Pliant Therapeutics (PLRX) Operating Expenses (2019 - 2026) Analysis & Trends
Pliant Therapeutics (PLRX) has 8 years of Operating Expenses data on file, last reported at $21.8 million in Q1 2026.
- Operating Expenses for Q1 2026 came in at $21.8 million, down 63.06% year-over-year; the trailing twelve-month figure through Mar 2026 was $119.2 million (down 49.25% YoY), and the FY2025 annual result was $156.4 million, down 31.52% from the prior year.
- Operating Expenses eased to $21.8 million in Q1 2026 per PLRX's latest filing, from $23.6 million in the prior quarter.
- Over five years, Operating Expenses peaked at $62.0 million in Q3 2024 and troughed at $21.8 million in Q1 2026.
- A 5-year average of $42.9 million and a median of $45.6 million in 2025 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2022 and 2026: Operating Expenses surged 48.0% in 2022, then plunged 63.06% in 2026.
- A 5-year view of Operating Expenses shows it stood at $39.4 million in 2022, then rose by 19.49% to $47.0 million in 2023, then climbed by 13.36% to $53.3 million in 2024, then tumbled by 55.78% to $23.6 million in 2025, then slipped by 7.66% to $21.8 million in 2026.
- Business Quant data shows PLRX's Operating Expenses at $21.8 million in Q1 2026, $23.6 million in Q4 2025, and $28.3 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | 15.76 Mn |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | -67.40 Mn |
| 10 | Pliant Therapeutics | 71.07 Mn | 71.07 Mn | - | 21.77 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 21.77 Mn |
| Dec 31, 2025 | 23.58 Mn |
| Sep 30, 2025 | 28.27 Mn |
| Jun 30, 2025 | 45.59 Mn |
| Mar 31, 2025 | 58.94 Mn |
| Dec 31, 2024 | 53.32 Mn |
| Sep 30, 2024 | 62.01 Mn |
| Jun 30, 2024 | 60.64 Mn |
| Mar 31, 2024 | 52.39 Mn |
| Dec 31, 2023 | 47.04 Mn |
| Sep 30, 2023 | 47.69 Mn |
| Jun 30, 2023 | 47.58 Mn |
| Mar 31, 2023 | 43.43 Mn |
| Dec 31, 2022 | 39.37 Mn |
| Sep 30, 2022 | 33.43 Mn |
| Jun 30, 2022 | 34.63 Mn |
| Mar 31, 2022 | 29.46 Mn |
| Dec 31, 2021 | 26.60 Mn |
| Sep 30, 2021 | 28.72 Mn |
| Jun 30, 2021 | 24.69 Mn |