Vaxcyte (PCVX) Operating Expenses (2019 - 2026)
Vaxcyte (PCVX) reported Operating Expenses of $345.8 million for Q1 2026, up 91.3% year-over-year from $180.8 million in Q1 2025, and up 26.09% quarter-over-quarter from $274.3 million in Q4 2025.
Vaxcyte (PCVX) Operating Expenses (2019 - 2026) Analysis & Trends
Vaxcyte (PCVX) has 8 years of Operating Expenses data on file, last reported at $345.8 million in Q1 2026.
- Operating Expenses for Q1 2026 came in at $345.8 million, up 91.3% year-over-year; the trailing twelve-month figure through Mar 2026 was $1.1 billion (up 71.22% YoY), and the FY2025 annual result was $923.7 million, up 62.18% from the prior year.
- Operating Expenses climbed to $345.8 million in Q1 2026 per PCVX's latest filing, from $274.3 million in the prior quarter.
- Over five years, Operating Expenses peaked at $345.8 million in Q1 2026 and troughed at $39.2 million in Q1 2022.
- A 5-year average of $149.4 million and a median of $139.9 million in 2024 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2022 and 2024: Operating Expenses jumped 190.07% in 2022, then decreased 17.55% in 2024.
- A 5-year view of Operating Expenses shows it stood at $86.6 million in 2022, then jumped by 127.18% to $196.7 million in 2023, then declined by 17.55% to $162.2 million in 2024, then surged by 69.13% to $274.3 million in 2025, then climbed by 26.09% to $345.8 million in 2026.
- Business Quant data shows PCVX's Operating Expenses at $345.8 million in Q1 2026, $274.3 million in Q4 2025, and $242.4 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 15.76 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | -67.40 Mn |
| 10 | Vaxcyte | 6.34 Bn | 6.34 Bn | - | 345.85 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 345.85 Mn |
| Dec 31, 2025 | 274.28 Mn |
| Sep 30, 2025 | 242.38 Mn |
| Jun 30, 2025 | 226.22 Mn |
| Mar 31, 2025 | 180.79 Mn |
| Dec 31, 2024 | 162.17 Mn |
| Sep 30, 2024 | 139.92 Mn |
| Jun 30, 2024 | 152.98 Mn |
| Mar 31, 2024 | 114.47 Mn |
| Dec 31, 2023 | 196.68 Mn |
| Sep 30, 2023 | 113.03 Mn |
| Jun 30, 2023 | 87.15 Mn |
| Mar 31, 2023 | 71.19 Mn |
| Dec 31, 2022 | 86.57 Mn |
| Sep 30, 2022 | 58.58 Mn |
| Jun 30, 2022 | 47.89 Mn |
| Mar 31, 2022 | 39.22 Mn |
| Dec 31, 2021 | 29.85 Mn |
| Sep 30, 2021 | 26.95 Mn |
| Jun 30, 2021 | 23.73 Mn |