Vaxcyte (PCVX) Operating Expenses (2019 - 2026)

Vaxcyte (PCVX) reported Operating Expenses of $345.8 million for Q1 2026, up 91.3% year-over-year from $180.8 million in Q1 2025, and up 26.09% quarter-over-quarter from $274.3 million in Q4 2025.

Vaxcyte (PCVX) Operating Expenses (2019 - 2026) Analysis & Trends

Vaxcyte (PCVX) has 8 years of Operating Expenses data on file, last reported at $345.8 million in Q1 2026.

  • Operating Expenses for Q1 2026 came in at $345.8 million, up 91.3% year-over-year; the trailing twelve-month figure through Mar 2026 was $1.1 billion (up 71.22% YoY), and the FY2025 annual result was $923.7 million, up 62.18% from the prior year.
  • Operating Expenses climbed to $345.8 million in Q1 2026 per PCVX's latest filing, from $274.3 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $345.8 million in Q1 2026 and troughed at $39.2 million in Q1 2022.
  • A 5-year average of $149.4 million and a median of $139.9 million in 2024 frame the typical range for Operating Expenses.
  • The sharpest annual moves came in 2022 and 2024: Operating Expenses jumped 190.07% in 2022, then decreased 17.55% in 2024.
  • A 5-year view of Operating Expenses shows it stood at $86.6 million in 2022, then jumped by 127.18% to $196.7 million in 2023, then declined by 17.55% to $162.2 million in 2024, then surged by 69.13% to $274.3 million in 2025, then climbed by 26.09% to $345.8 million in 2026.
  • Business Quant data shows PCVX's Operating Expenses at $345.8 million in Q1 2026, $274.3 million in Q4 2025, and $242.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 4.33 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 2.97 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 15.76 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.82 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 574,669.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.71 Bn 91.71 Bn - -67.40 Mn
10 Vaxcyte 6.34 Bn 6.34 Bn - 345.85 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 345.85 Mn
Dec 31, 2025 274.28 Mn
Sep 30, 2025 242.38 Mn
Jun 30, 2025 226.22 Mn
Mar 31, 2025 180.79 Mn
Dec 31, 2024 162.17 Mn
Sep 30, 2024 139.92 Mn
Jun 30, 2024 152.98 Mn
Mar 31, 2024 114.47 Mn
Dec 31, 2023 196.68 Mn
Sep 30, 2023 113.03 Mn
Jun 30, 2023 87.15 Mn
Mar 31, 2023 71.19 Mn
Dec 31, 2022 86.57 Mn
Sep 30, 2022 58.58 Mn
Jun 30, 2022 47.89 Mn
Mar 31, 2022 39.22 Mn
Dec 31, 2021 29.85 Mn
Sep 30, 2021 26.95 Mn
Jun 30, 2021 23.73 Mn