Growth Metrics

Puma Biotechnology (PBYI) Gross Margin (2017 - 2025)

Puma Biotechnology (PBYI) has disclosed Gross Margin for 9 consecutive years, with 69.35% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Gross Margin fell 709.0% year-over-year to 69.35%, compared with a TTM value of 74.53% through Dec 2025, up 248.0%, and an annual FY2025 reading of 74.53%, up 248.0% over the prior year.
  • Gross Margin was 69.35% for Q4 2025 at Puma Biotechnology, down from 77.65% in the prior quarter.
  • Across five years, Gross Margin topped out at 80.79% in Q4 2022 and bottomed at 63.87% in Q3 2024.
  • Average Gross Margin over 5 years is 75.18%, with a median of 76.49% recorded in 2024.
  • The sharpest move saw Gross Margin crashed -1449bps in 2023, then surged 1378bps in 2025.
  • Year by year, Gross Margin stood at 78.51% in 2021, then increased by 3bps to 80.79% in 2022, then fell by -18bps to 66.3% in 2023, then rose by 15bps to 76.44% in 2024, then decreased by -9bps to 69.35% in 2025.
  • Business Quant data shows Gross Margin for PBYI at 69.35% in Q4 2025, 77.65% in Q3 2025, and 76.54% in Q2 2025.