Alnylam Pharmaceuticals (ALNY) Gross Margin (2018 - 2026)
Alnylam Pharmaceuticals (ALNY) reported Gross Margin of 82.22% for Q1 2026, up 21616.0% on a YoY basis from N/an in Q1 2025, and up 8.76% quarter-over-quarter from 75.6% in Q4 2025.
Alnylam Pharmaceuticals (ALNY) Gross Margin (2018 - 2026) Analysis & Trends
Alnylam Pharmaceuticals has reported Gross Margin for 9 years, with the latest figure at 82.22% in Q1 2026.
- For the quarter ending Q1 2026, Gross Margin rose 21616.0% year-over-year to 82.22%; the trailing twelve-month figure through Mar 2026 stood at 81.0% (down 94.0% YoY), and the FY2025 full-year result was 81.77%, down 460.0% from the prior year.
- Gross Margin for Q1 2026 stood at 82.22%, up from 75.6% in the prior quarter.
- The five-year high for Gross Margin was 89.8% in Q2 2024, with the low at 133.94% in Q1 2025.
- Historically, Gross Margin has averaged 71.62% across 5 years, with a median of 84.21% in 2025.
- Annual changes were most pronounced in 2025 — Gross Margin plunged 22290 bps — and 2026, when it jumped 21616 bps.
- Alnylam Pharmaceuticals' Gross Margin stood at 86.22% in 2022, then declined by 3 bps to 83.63% in 2023, then decreased by 1 bps to 82.69% in 2024, then declined by 9 bps to 75.6% in 2025, then climbed by 9 bps to 82.22% in 2026.
- The last three Gross Margin figures came in at 82.22% (Q1 2026), 75.6% (Q4 2025), and 84.21% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Alnylam Pharmaceuticals | 37.04 Bn | 34.03 Bn | 959.66 Mn | 82.22% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 82.22% |
| Dec 31, 2025 | 75.60% |
| Sep 30, 2025 | 84.21% |
| Jun 30, 2025 | 81.64% |
| Mar 31, 2025 | -133.94% |
| Dec 31, 2024 | 82.69% |
| Sep 30, 2024 | 83.63% |
| Jun 30, 2024 | 89.80% |
| Mar 31, 2024 | 88.95% |
| Dec 31, 2023 | 83.63% |
| Sep 30, 2023 | 89.41% |
| Jun 30, 2023 | 76.37% |
| Mar 31, 2023 | 87.02% |
| Dec 31, 2022 | 86.22% |
| Sep 30, 2022 | 86.19% |
| Jun 30, 2022 | 84.86% |
| Mar 31, 2022 | 89.00% |
| Dec 31, 2021 | 86.99% |
| Sep 30, 2021 | 85.03% |
| Jun 30, 2021 | 86.28% |