Alnylam Pharmaceuticals (ALNY) Gross Margin (2018 - 2026)

Alnylam Pharmaceuticals (ALNY) reported Gross Margin of 82.22% for Q1 2026, up 21616.0% on a YoY basis from N/an in Q1 2025, and up 8.76% quarter-over-quarter from 75.6% in Q4 2025.

Alnylam Pharmaceuticals (ALNY) Gross Margin (2018 - 2026) Analysis & Trends

Alnylam Pharmaceuticals has reported Gross Margin for 9 years, with the latest figure at 82.22% in Q1 2026.

  • For the quarter ending Q1 2026, Gross Margin rose 21616.0% year-over-year to 82.22%; the trailing twelve-month figure through Mar 2026 stood at 81.0% (down 94.0% YoY), and the FY2025 full-year result was 81.77%, down 460.0% from the prior year.
  • Gross Margin for Q1 2026 stood at 82.22%, up from 75.6% in the prior quarter.
  • The five-year high for Gross Margin was 89.8% in Q2 2024, with the low at 133.94% in Q1 2025.
  • Historically, Gross Margin has averaged 71.62% across 5 years, with a median of 84.21% in 2025.
  • Annual changes were most pronounced in 2025 — Gross Margin plunged 22290 bps — and 2026, when it jumped 21616 bps.
  • Alnylam Pharmaceuticals' Gross Margin stood at 86.22% in 2022, then declined by 3 bps to 83.63% in 2023, then decreased by 1 bps to 82.69% in 2024, then declined by 9 bps to 75.6% in 2025, then climbed by 9 bps to 82.22% in 2026.
  • The last three Gross Margin figures came in at 82.22% (Q1 2026), 75.6% (Q4 2025), and 84.21% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Alnylam Pharmaceuticals 37.04 Bn 34.03 Bn 959.66 Mn 82.22%

Historic Data

Download Data
DateValue
Mar 31, 2026 82.22%
Dec 31, 2025 75.60%
Sep 30, 2025 84.21%
Jun 30, 2025 81.64%
Mar 31, 2025 -133.94%
Dec 31, 2024 82.69%
Sep 30, 2024 83.63%
Jun 30, 2024 89.80%
Mar 31, 2024 88.95%
Dec 31, 2023 83.63%
Sep 30, 2023 89.41%
Jun 30, 2023 76.37%
Mar 31, 2023 87.02%
Dec 31, 2022 86.22%
Sep 30, 2022 86.19%
Jun 30, 2022 84.86%
Mar 31, 2022 89.00%
Dec 31, 2021 86.99%
Sep 30, 2021 85.03%
Jun 30, 2021 86.28%