Growth Metrics

Alnylam Pharmaceuticals (ALNY) Gross Margin (2019 - 2025)

Alnylam Pharmaceuticals (ALNY) has disclosed Gross Margin for 7 consecutive years, with 83.88% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Gross Margin rose 119.0% year-over-year to 83.88%, compared with a TTM value of 81.77% through Dec 2025, down 460.0%, and an annual FY2025 reading of 81.77%, down 460.0% over the prior year.
  • Gross Margin was 83.88% for Q4 2025 at Alnylam Pharmaceuticals, roughly flat from 84.21% in the prior quarter.
  • Across five years, Gross Margin topped out at 89.8% in Q2 2024 and bottomed at 133.94% in Q1 2025.
  • Average Gross Margin over 5 years is 74.45%, with a median of 85.61% recorded in 2021.
  • The sharpest move saw Gross Margin surged 1344bps in 2024, then plummeted -22290bps in 2025.
  • Year by year, Gross Margin stood at 86.99% in 2021, then dropped by -1bps to 86.22% in 2022, then dropped by -3bps to 83.63% in 2023, then dropped by -1bps to 82.69% in 2024, then grew by 1bps to 83.88% in 2025.
  • Business Quant data shows Gross Margin for ALNY at 83.88% in Q4 2025, 84.21% in Q3 2025, and 81.64% in Q2 2025.