Alnylam Pharmaceuticals (ALNY) Gross Margin (2017 - 2026)
Alnylam Pharmaceuticals (ALNY) reported Gross Margin of 76.90% for Q2 2026, down 4.75 percentage points from 81.64% a year earlier and down 5.32 percentage points from the prior quarter.
Alnylam Pharmaceuticals (ALNY) Gross Margin (2017 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Alnylam Pharmaceuticals' Gross Margin came in at 79.79%, down 4.62 percentage points year-over-year; for FY2025, it was 81.77%, down 4.60 percentage points from FY2024.
- Gross Margin has a five-year change of -3.18 percentage points (FY2020 to FY2025).
- By year, Gross Margin came in at 86.37% in FY2024 (+1.04 pp), 85.33% in FY2023 (-1.16 pp), 86.49% in FY2022 (+0.11 pp) and 86.38% in FY2021 (+1.43 pp).
- Five-year quarterly Gross Margin spans a low of 75.60% in Q4 2025 and a high of 89.80% in Q2 2024.
- Year over year, Gross Margin gained in 1 of the last six quarters, with an average year-over-year change of -4.36 percentage points.
- The high point for year-over-year Gross Margin in five years was Q2 2024 (a gain of 13.44 percentage points); the low point was Q2 2023 (a drop of 8.49 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at 82.22% (Q1 2026), 75.60% (Q4 2025) and 84.21% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 83.88% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 68.12% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 75.38% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 72.95% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 88.03% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 73.10% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 81.07% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 75.71% |
| 10 | Alnylam Pharmaceuticals | 20.30 Bn | 7.49 Bn | 1.10 Bn | 75.19% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 75.19% |
| Jun 30, 2026 | 76.90% |
| Mar 31, 2026 | 82.22% |
| Dec 31, 2025 | 75.60% |
| Sep 30, 2025 | 84.21% |
| Jun 30, 2025 | 81.64% |
| Dec 31, 2024 | 82.69% |
| Sep 30, 2024 | 83.63% |
| Jun 30, 2024 | 89.80% |
| Mar 31, 2024 | 88.95% |
| Dec 31, 2023 | 83.63% |
| Sep 30, 2023 | 89.41% |
| Jun 30, 2023 | 76.37% |
| Mar 31, 2023 | 87.02% |
| Dec 31, 2022 | 86.22% |
| Sep 30, 2022 | 86.19% |
| Jun 30, 2022 | 84.86% |
| Mar 31, 2022 | 89.00% |
| Dec 31, 2021 | 86.99% |
| Sep 30, 2021 | 85.03% |
Alnylam Pharmaceuticals Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "ALNY", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY");
const data = await res.json();