Puma Biotechnology, Inc. (PBYI) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

2,895,844Shares held by institutions

$17,751,524Value of institutional holdings

64.49%Institutional ownership %

-7.51%Shares Changed QoQ

119No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Puma Biotechnology, Inc. (NASDAQ:PBYI) appears in 146 institutional 13F filings for the quarter ending December 2025.

These investors collectively held 69.5% of Puma Biotechnology's outstanding shares in December 2025, up from 67.7% in September 2025.
Their total shares held in PBYI increased 7.05% quarter over quarter, and separately, investors owning Puma Biotechnology increased 29.2% from a year ago.
During the quarter, 79 of these 146 funds increased positions in PBYI, 42 reduced exposure, and 25 held steady.
In total, institutional investors held 35.4Mn shares in Puma Biotechnology as of December 2025, up by 2.33Mn shares quarter on quarter, and up 613.81K shares year over year.
ACORN CAPITAL ADVISORS, LLC leads ownership in PBYI with 4.13Mn shares as of December 31, 2025, equal to 8.11% of outstanding shares.
Top purchasers of PBYI stock for the quarter ending December 2025 included Goldman Sachs Group Inc (559.34K), AQR CAPITAL MANAGEMENT LLC (535.93K), BRIDGEWAY CAPITAL MANAGEMENT, LLC (339.92K), O'SHAUGHNESSY ASSET MANAGEMENT, LLC (292.11K), Empowered Funds, LLC (252.81K).
The biggest sellers of Puma Biotechnology for the quarter ending December 2025 included Russell Investments Group, Ltd. (713.04K), UBS Group AG (248.78K), Universal- Beteiligungs- und Servicegesellschaft mbH (159.2K), LSV ASSET MANAGEMENT (155.12K), LOS ANGELES CAPITAL MANAGEMENT LLC (125.92K).
Per Business Quant data, the top 10 holders of Puma Biotechnology for the quarter ending December 2025 are ACORN CAPITAL ADVISORS, LLC (4.13Mn), VANGUARD GROUP INC (3.8Mn), BlackRock, Inc. (3.64Mn), RENAISSANCE TECHNOLOGIES LLC (2.12Mn), ACADIAN ASSET MANAGEMENT LLC (2.02Mn), AMERICAN CENTURY COMPANIES INC (1.65Mn), DIMENSIONAL FUND ADVISORS LP (1.34Mn), O'SHAUGHNESSY ASSET MANAGEMENT, LLC (1.12Mn), GEODE CAPITAL MANAGEMENT, LLC (994.34K), State Street Corp (877.08K).

146 Institutional Holders

2,895,844 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	64,711	1.81%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	106,028	2.87%	$0.00
ACORN CAPITAL ADVISORS, LLC	31 Dec, 2025	0	0.00%	$0.00
Barclays Plc	31 Dec, 2025	-76,468	-48.43%	$0.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	-27,400	-1.27%	$0.00
RITHOLTZ WEALTH MANAGEMENT	31 Dec, 2025	223,234	47.42%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	318	0.00%	$0.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	-28,482	-1.39%	$0.00
Russell Investments Group, Ltd.	31 Dec, 2025	-713,040	-73.91%	$0.00
AMERICAN CENTURY COMPANIES INC	31 Dec, 2025	166,949	11.26%	$0.00
UBS Group AG	31 Dec, 2025	-248,779	-66.15%	$0.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	67,725	5.32%	$0.00
Qube Research & Technologies Ltd	31 Dec, 2025	-43,996	-28.29%	$0.00
O'SHAUGHNESSY ASSET MANAGEMENT, LLC	31 Dec, 2025	292,108	35.27%	$0.00
Round Rock Advisors LLC	31 Dec, 2025	39,646	60.62%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	10,823	1.10%	$0.00
WINTON GROUP Ltd	31 Dec, 2025	35,835	58.44%	$0.00
State Street Corp	31 Dec, 2025	128,419	17.15%	$0.00
Haven Private, LLC	31 Dec, 2025	92,083	0.00%	$0.00
Connor, Clark & Lunn Investment Management Ltd.	31 Dec, 2025	-68,171	-7.23%	$0.00

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