Puma Biotechnology, Inc. (PBYI) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

50,370,723Shares Outstanding

5,514,291Shares held by institutions

$32,313,745Value of institutional holdings

68.50%Institutional ownership %

9.71%Shares Changed QoQ

132No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of September 2025 show that 132 institutional investors hold a position in Puma Biotechnology, Inc. (NASDAQ:PBYI).

These investors collectively held 68.5% of the company's total shares outstanding in September 2025, up from 65.0% in June 2025.
In percentage terms, this reflects as a holdings change of 9.71% quarter on quarter, and an increase of 33.33% year over year.
A review of institutional activity for Puma Biotechnology shows 63 of 132 filers increasing their positions, while 41 reduced their stake, and 28 remained unchanged.
The aggregate institutional position in Puma Biotechnology now stands at 34.51Mn shares as of September 2025, after investors increased their holdings (up by 3.05Mn shares quarter on quarter which is up 4.81Mn shares year over year).
ACORN CAPITAL ADVISORS, LLC's holding of 4.13Mn shares as of September 30, 2025 makes it the primary institutional investor in Puma Biotechnology, owning 8.20% of the stock.
Among the most significant buyers of Puma Biotechnology during September 2025 were Russell Investments Group, Ltd. (964.67K), MARSHALL WACE, LLP (484.13K), O'SHAUGHNESSY ASSET MANAGEMENT, LLC (390.56K), RENAISSANCE TECHNOLOGIES LLC (276.50K), RITHOLTZ WEALTH MANAGEMENT (273.78K).
Leading sellers of Puma Biotechnology stock in September 2025 included BlackRock, Inc. (257.84K), MILLENNIUM MANAGEMENT LLC (228.98K), TWO SIGMA ADVISERS, LP (172.50K), LOS ANGELES CAPITAL MANAGEMENT LLC (171.43K), D. E. Shaw & Co., Inc. (142.18K).
The top 10 institutional holders of Puma Biotechnology for the quarter ending September 2025 included ACORN CAPITAL ADVISORS, LLC (4.13Mn), VANGUARD GROUP INC (3.69Mn), BlackRock, Inc. (3.58Mn), RENAISSANCE TECHNOLOGIES LLC (2.15Mn), ACADIAN ASSET MANAGEMENT LLC (2.05Mn), AMERICAN CENTURY COMPANIES INC (1.48Mn), DIMENSIONAL FUND ADVISORS LP (1.27Mn), GEODE CAPITAL MANAGEMENT, LLC (983.52K), Russell Investments Group, Ltd. (964.69K), Connor, Clark & Lunn Investment Management Ltd. (943.47K).

132 Institutional Holders

5,514,291 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ACORN CAPITAL ADVISORS, LLC	30 Sep, 2025	4,131,299	0	0.00%	$21,937,198.00
VANGUARD GROUP INC	30 Sep, 2025	3,691,720	-14,732	-0.40%	$19,603,033.00
BlackRock, Inc.	30 Sep, 2025	3,577,877	-257,838	-6.72%	$18,998,527.00
RENAISSANCE TECHNOLOGIES LLC	30 Sep, 2025	2,151,213	276,500	14.75%	$11,422,941.00
ACADIAN ASSET MANAGEMENT LLC	30 Sep, 2025	2,053,305	45,159	2.25%	$10,900.00
AMERICAN CENTURY COMPANIES INC	30 Sep, 2025	1,483,188	140,913	10.50%	$7,875,728.00
DIMENSIONAL FUND ADVISORS LP	30 Sep, 2025	1,271,878	121,838	10.59%	$6,751,930.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	983,522	11,848	1.22%	$5,223,376.00
Russell Investments Group, Ltd.	30 Sep, 2025	964,693	964,673	4,823,365.00%	$5,122,519.00
Connor, Clark & Lunn Investment Management Ltd.	30 Sep, 2025	943,472	43,216	4.80%	$5,009,836.00
KENNEDY CAPITAL MANAGEMENT LLC	30 Sep, 2025	867,630	-119,371	-12.09%	$4,607,115.00
O'SHAUGHNESSY ASSET MANAGEMENT, LLC	30 Sep, 2025	828,221	390,561	89.24%	$4,397,854.00
STATE STREET CORP	30 Sep, 2025	748,658	14,052	1.91%	$3,975,374.00
LSV ASSET MANAGEMENT	30 Sep, 2025	559,921	24,181	4.51%	$2,973.00
MARSHALL WACE, LLP	30 Sep, 2025	557,548	484,133	659.45%	$2,960,578.00
NORTHERN TRUST CORP	30 Sep, 2025	526,736	224,721	74.41%	$2,796,968.00
D. E. Shaw & Co., Inc.	30 Sep, 2025	498,598	-142,182	-22.19%	$2,647,555.00
RITHOLTZ WEALTH MANAGEMENT	30 Sep, 2025	470,767	273,782	138.99%	$2,499,773.00
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	30 Sep, 2025	464,734	13,101	2.90%	$2,467,738.00
GLOBEFLEX CAPITAL L P	30 Sep, 2025	452,606	0	0.00%	$2,403,338.00

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Puma Biotechnology, Inc. (PBYI) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

132 Institutional Holders

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