Nuvalent (NUVL) Operating Expenses (2020 - 2026)

Nuvalent (NUVL) reported Operating Expenses of $119.4 million for Q1 2026, up 25.94% on a YoY basis from $94.8 million in Q1 2025, and down 69.23% quarter-over-quarter from $388.0 million in Q4 2025.

Nuvalent (NUVL) Operating Expenses (2020 - 2026) Analysis & Trends

Nuvalent has reported Operating Expenses for 7 years, with the latest figure at $119.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses rose 25.94% year-over-year to $119.4 million; the trailing twelve-month figure through Mar 2026 stood at $526.7 million (up 781.74% YoY), and the FY2025 full-year result was $414.3 million, up 2265.98% from the prior year.
  • Operating Expenses for Q1 2026 stood at $119.4 million, down from $388.0 million in the prior quarter.
  • The five-year high for Operating Expenses was $388.0 million in Q4 2025, with the low at -$176.6 million in Q4 2024.
  • Historically, Operating Expenses has averaged $48.5 million across 5 years, with a median of $30.2 million in 2023.
  • Annual changes were most pronounced in 2024 — Operating Expenses tumbled 480.21% — and 2025, when it soared 2986.33%.
  • Nuvalent's Operating Expenses stood at $29.3 million in 2022, then surged by 58.49% to $46.4 million in 2023, then plunged by 480.21% to -$176.6 million in 2024, then jumped by 319.77% to $388.0 million in 2025, then slumped by 69.23% to $119.4 million in 2026.
  • The last three Operating Expenses figures came in at $119.4 million (Q1 2026), $388.0 million (Q4 2025), and $11.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 788,338.31 Bn 788,338.28 Bn - 4.33 Mn
2 Belite Bio 56,560.00 Bn 56,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,329.30 Bn 17,329.30 Bn - 2.97 Mn
4 Legend Biotech 3,341.00 Bn 3,340.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,727.91 Bn 1,727.91 Bn - 15.76 Mn
6 Evaxion A 1,536.68 Bn 1,536.67 Bn - -3.82 Mn
7 Psyence Biomedical 238.34 Bn 238.33 Bn - 574,669.00
8 Vertex Pharmaceuticals 113.42 Bn 106.17 Bn 2.59 Bn 1.85 Bn
9 Abivax 95.45 Bn 95.45 Bn - -67.40 Mn
10 Nuvalent 9.69 Bn 9.69 Bn - 119.41 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 119.41 Mn
Dec 31, 2025 388.02 Mn
Sep 30, 2025 11.46 Mn
Jun 30, 2025 7.82 Mn
Mar 31, 2025 94.81 Mn
Dec 31, 2024 -176.56 Mn
Sep 30, 2024 76.33 Mn
Jun 30, 2024 65.15 Mn
Mar 31, 2024 3.07 Mn
Dec 31, 2023 46.44 Mn
Sep 30, 2023 38.78 Mn
Jun 30, 2023 34.06 Mn
Mar 31, 2023 30.21 Mn
Dec 31, 2022 29.30 Mn
Sep 30, 2022 20.39 Mn
Jun 30, 2022 18.73 Mn
Mar 31, 2022 17.69 Mn
Dec 31, 2021 17.38 Mn
Sep 30, 2021 12.43 Mn
Jun 30, 2021 9.85 Mn