Nuvalent (NUVL) Operating Expenses (2020 - 2026)

Nuvalent's (NUVL) quarterly Operating Expenses came in at $119.4 million in Q1 2026, up 25.94% YoY from $94.8 million in Q1 2025, and up 16.8% on a QoQ basis from $102.2 million in Q4 2025.

Nuvalent (NUVL) Operating Expenses (2020 - 2026) Analysis & Trends

Nuvalent (NUVL) has 7 years of Operating Expenses data on file, last reported at $119.4 million in Q1 2026.

  • Quarterly Operating Expenses rose 25.94% year-over-year to $119.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $337.7 million (up 2907.32% YoY) and the FY2025 annual result came in at $414.3 million, up 2265.98% from the prior year.
  • Operating Expenses grew to $119.4 million in Q1 2026, from $102.2 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $119.4 million in Q1 2026 to a low of -$176.6 million in Q4 2024.
  • A 5-year average of $23.2 million and a median of $30.2 million in 2023 frame the typical range for Operating Expenses.
  • The widest YoY moves for Operating Expenses: up 187.05% in 2022, down 385.92% in 2022.
  • Tracing NUVL's Operating Expenses over 5 years: stood at -$49.7 million in 2022, then tumbled by 88.71% to -$93.8 million in 2023, then plunged by 88.3% to -$176.6 million in 2024, then surged by 157.9% to $102.2 million in 2025, then rose by 16.8% to $119.4 million in 2026.
  • The last three Operating Expenses figures came in at $119.4 million (Q1 2026), $102.2 million (Q4 2025), and $11.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 2.89 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.21 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 4,978.15
7 Royalty Pharma 33.72 Bn 35.84 Bn - 541.02 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.06 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 427.03 Mn
10 Nuvalent 9.10 Bn 9.10 Bn - 119.41 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 119.41 Mn
Dec 31, 2025 102.23 Mn
Sep 30, 2025 11.46 Mn
Jun 30, 2025 104.57 Mn
Mar 31, 2025 94.81 Mn
Dec 31, 2024 -176.56 Mn
Sep 30, 2024 4.57 Mn
Jun 30, 2024 65.15 Mn
Mar 31, 2024 52.59 Mn
Dec 31, 2023 -93.76 Mn
Sep 30, 2023 38.78 Mn
Jun 30, 2023 34.06 Mn
Mar 31, 2023 30.21 Mn
Dec 31, 2022 -49.69 Mn
Sep 30, 2022 20.39 Mn
Jun 30, 2022 18.73 Mn
Mar 31, 2022 17.69 Mn
Dec 31, 2021 17.38 Mn
Sep 30, 2021 12.43 Mn
Jun 30, 2021 9.85 Mn