Nuvalent (NUVL) Operating Expenses (2020 - 2026)

Nuvalent (NUVL) posted Operating Expenses of $119.4 million for Q1 2026, up 16.8% on a QoQ basis from $102.2 million in Q4 2025, and up 25.94% year-over-year from $94.8 million in Q1 2025.

Nuvalent (NUVL) Operating Expenses (2020 - 2026) Analysis & Trends

Nuvalent's Operating Expenses history runs 7 years deep, the most recent figure standing at $119.4 million for Q1 2026.

  • Quarterly Operating Expenses rose 25.94% year-over-year to $119.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $337.7 million (up 2907.32% YoY) and the FY2025 annual result came in at $414.3 million, up 2265.98% from the prior year.
  • Operating Expenses was $119.4 million for Q1 2026 at Nuvalent, up from $102.2 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $119.4 million in Q1 2026 and bottomed at -$176.6 million in Q4 2024.
  • A 5-year average of $23.2 million and a median of $30.2 million in 2023 frame the typical range for Operating Expenses.
  • Peak annual rise in Operating Expenses reached 187.05% in 2022, while the deepest fall reached 385.92% in 2022.
  • Nuvalent's Operating Expenses stood at -$49.7 million in 2022, then sank by 88.71% to -$93.8 million in 2023, then slumped by 88.3% to -$176.6 million in 2024, then jumped by 157.9% to $102.2 million in 2025, then advanced by 16.8% to $119.4 million in 2026.
  • Business Quant data shows NUVL's Operating Expenses at $119.4 million in Q1 2026, $102.2 million in Q4 2025, and $11.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Nuvalent 9.75 Bn 9.75 Bn - 119.41 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 119.41 Mn
Dec 31, 2025 102.23 Mn
Sep 30, 2025 11.46 Mn
Jun 30, 2025 104.57 Mn
Mar 31, 2025 94.81 Mn
Dec 31, 2024 -176.56 Mn
Sep 30, 2024 4.57 Mn
Jun 30, 2024 65.15 Mn
Mar 31, 2024 52.59 Mn
Dec 31, 2023 -93.76 Mn
Sep 30, 2023 38.78 Mn
Jun 30, 2023 34.06 Mn
Mar 31, 2023 30.21 Mn
Dec 31, 2022 -49.69 Mn
Sep 30, 2022 20.39 Mn
Jun 30, 2022 18.73 Mn
Mar 31, 2022 17.69 Mn
Dec 31, 2021 17.38 Mn
Sep 30, 2021 12.43 Mn
Jun 30, 2021 9.85 Mn