Nuvalent, Inc. (NUVL) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

72,021,765Shares Outstanding

6,216,704Shares held by institutions

$635,595,817Value of institutional holdings

105.49%Institutional ownership %

8.50%Shares Changed QoQ

224No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

A total of 224 institutions have reported a stake in Nuvalent, Inc. (NASDAQ:NUVL) as of December 2025, according to recent 13F filings with the SEC.

The collective stake of institutional investors in Nuvalent moved to 105.5% in December 2025, a shift up from the 100.6% reported for September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 8.50%, with a year-over-year an increase of 4.19% in the count of filers.
A review of institutional activity for Nuvalent shows 150 of 224 filers increasing their positions, while 46 reduced their stake, and 28 remained unchanged.
The total number of shares held by institutions in Nuvalent increased to 75.98Mn as of December 2025, a net change of up by 5.95Mn shares quarter on quarter, and up 4.70Mn shares year over year.
DEERFIELD MANAGEMENT COMPANY, L.P.'s holding of 17.25Mn shares as of December 31, 2025 makes it the primary institutional investor in Nuvalent, owning 23.95% of the stock.
Among the most significant buyers of Nuvalent during December 2025 were Bellevue Group AG (1.04Mn), FMR LLC (839.65K), ALLIANCEBERNSTEIN L.P. (735.48K), BlackRock, Inc. (719.40K), VANGUARD GROUP INC (639.26K).
Leading sellers of Nuvalent stock in December 2025 included Vestal Point Capital, LP (1.05Mn), Commodore Capital LP (850.00K), DEERFIELD MANAGEMENT COMPANY, L.P. (742.57K), JANUS HENDERSON GROUP PLC (689.10K), T. Rowe Price Investment Management, Inc. (652.46K).
The top 10 institutional holders of Nuvalent for the quarter ending December 2025 included DEERFIELD MANAGEMENT COMPANY, L.P. (17.25Mn), FMR LLC (10.85Mn), Paradigm Biocapital Advisors LP (5.27Mn), VANGUARD GROUP INC (5.24Mn), BlackRock, Inc. (4.81Mn), WELLINGTON MANAGEMENT GROUP LLP (2.46Mn), JPMORGAN CHASE & CO (2.21Mn), RA CAPITAL MANAGEMENT, L.P. (1.88Mn), STATE STREET CORP (1.86Mn), PERCEPTIVE ADVISORS LLC (1.67Mn).

224 Institutional Holders

6,216,704 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
DEERFIELD MANAGEMENT COMPANY, L.P.	31 Dec, 2025	17,248,450	-742,574	-4.13%	$1,735,021,586.00
FMR LLC	31 Dec, 2025	10,852,884	839,647	8.39%	$1,091,691,628.00
Paradigm Biocapital Advisors LP	31 Dec, 2025	5,269,433	0	0.00%	$530,052,265.00
VANGUARD GROUP INC	31 Dec, 2025	5,244,271	639,264	13.88%	$527,521,219.00
BlackRock, Inc.	31 Dec, 2025	4,805,198	719,403	17.61%	$483,354,866.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	2,461,823	160,958	7.00%	$247,634,775.00
JPMORGAN CHASE & CO	31 Dec, 2025	2,205,251	531,242	31.73%	$221,826,288.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	1,880,057	633,601	50.83%	$189,114,934.00
STATE STREET CORP	31 Dec, 2025	1,864,675	289,928	18.41%	$187,567,658.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	1,665,105	102,769	6.58%	$167,492,912.00
Polar Capital Holdings Plc	31 Dec, 2025	1,536,859	514,634	50.34%	$154,592,647.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	1,499,574	-689,100	-31.48%	$150,822,342.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,238,234	144,241	13.18%	$124,575,027.00
Bellevue Group AG	31 Dec, 2025	1,037,468	1,037,468	0.00%	$104,358,906.00
BRAIDWELL LP	31 Dec, 2025	821,406	-191,576	-18.91%	$82,625,230.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	785,445	735,477	1,471.90%	$79,007,913.00
Fairmount Funds Management LLC	31 Dec, 2025	727,563	0	0.00%	$73,185,562.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	643,000	68,500	11.92%	$64,679,370.00
Woodline Partners LP	31 Dec, 2025	610,459	-459,061	-42.92%	$61,406,071.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	594,459	150,023	33.76%	$59,796,631.00

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