Nuvalent (NUVL) EBITDA (2020 - 2026)

Nuvalent's (NUVL) quarterly EBITDA came in at -$119.4 million in Q1 2026, down 25.94% YoY from -$161.2 million in Q1 2025, and down 16.8% on a QoQ basis from -$102.2 million in Q4 2025.

Nuvalent (NUVL) EBITDA (2020 - 2026) Analysis & Trends

Nuvalent (NUVL) has 7 years of EBITDA data on file, last reported at -$119.4 million in Q1 2026.

  • Quarterly EBITDA fell 25.94% year-over-year to -$119.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$438.9 million (down 36.05% YoY) and the FY2025 annual result came in at -$414.3 million, down 47.77% from the prior year.
  • EBITDA slipped to -$119.4 million in Q1 2026, from -$102.2 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$17.7 million in Q1 2022 to a low of -$119.4 million in Q1 2026.
  • A 5-year average of -$61.7 million and a median of -$52.6 million in 2024 frame the typical range for EBITDA.
  • Annual changes were most pronounced in 2022 — EBITDA sank 187.05% — and 2025, when it fell 18.46%.
  • Tracing NUVL's EBITDA over 5 years: stood at -$29.3 million in 2022, then plunged by 58.49% to -$46.4 million in 2023, then plunged by 85.84% to -$86.3 million in 2024, then fell by 18.46% to -$102.2 million in 2025, then decreased by 16.8% to -$119.4 million in 2026.
  • The last three EBITDA figures came in at -$119.4 million (Q1 2026), -$102.2 million (Q4 2025), and -$112.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Bn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Nuvalent 9.10 Bn 9.10 Bn - -119.41 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -119.41 Mn
Dec 31, 2025 -102.23 Mn
Sep 30, 2025 -112.70 Mn
Jun 30, 2025 -104.57 Mn
Mar 31, 2025 -94.81 Mn
Dec 31, 2024 -86.30 Mn
Sep 30, 2024 -76.33 Mn
Jun 30, 2024 -65.15 Mn
Mar 31, 2024 -52.59 Mn
Dec 31, 2023 -46.44 Mn
Sep 30, 2023 -38.78 Mn
Jun 30, 2023 -34.06 Mn
Mar 31, 2023 -30.21 Mn
Dec 31, 2022 -29.30 Mn
Sep 30, 2022 -20.39 Mn
Jun 30, 2022 -18.73 Mn
Mar 31, 2022 -17.69 Mn
Dec 31, 2021 -17.38 Mn
Sep 30, 2021 -12.43 Mn
Jun 30, 2021 -9.85 Mn