Nuvalent (NUVL) EBITDA (2020 - 2026)

Nuvalent (NUVL) reported EBITDA of -$113.0 million for Q1 2026, down 35.04% on a YoY basis from -$173.9 million in Q1 2025, and up 4.83% quarter-over-quarter from -$118.7 million in Q4 2025.

Nuvalent (NUVL) EBITDA (2020 - 2026) Analysis & Trends

Nuvalent has reported EBITDA for 7 years, with the latest figure at -$113.0 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 35.04% year-over-year to -$113.0 million; the trailing twelve-month figure through Mar 2026 stood at -$452.3 million (down 51.43% YoY), and the FY2025 full-year result was -$423.0 million, down 62.15% from the prior year.
  • EBITDA for Q1 2026 stood at -$113.0 million, up from -$118.7 million in the prior quarter.
  • The five-year high for EBITDA was -$18.3 million in Q1 2022, with the low at -$121.4 million in Q3 2025.
  • Historically, EBITDA has averaged -$59.1 million across 5 years, with a median of -$45.8 million in 2024.
  • Annual changes were most pronounced in 2022 — EBITDA sank 170.3% — and 2026, when it slumped 35.04%.
  • Nuvalent's EBITDA stood at -$25.8 million in 2022, then plunged by 43.49% to -$37.0 million in 2023, then plunged by 106.21% to -$76.2 million in 2024, then slumped by 55.81% to -$118.7 million in 2025, then rose by 4.83% to -$113.0 million in 2026.
  • The last three EBITDA figures came in at -$113.0 million (Q1 2026), -$118.7 million (Q4 2025), and -$121.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 788,338.31 Bn 788,338.28 Bn - -
2 Belite Bio 56,560.00 Bn 56,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,329.30 Bn 17,329.30 Bn - -13.63 Mn
4 Legend Biotech 3,341.00 Bn 3,340.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,727.91 Bn 1,727.91 Bn - -14.44 Mn
6 Evaxion A 1,536.68 Bn 1,536.67 Bn - -3.82 Mn
7 Psyence Biomedical 238.34 Bn 238.33 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.42 Bn 106.17 Bn 2.59 Bn 1.14 Bn
9 Abivax 95.45 Bn 95.45 Bn - -65.83 Mn
10 Nuvalent 9.69 Bn 9.69 Bn - -112.99 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -112.99 Mn
Dec 31, 2025 -118.72 Mn
Sep 30, 2025 -121.43 Mn
Jun 30, 2025 -99.14 Mn
Mar 31, 2025 -83.67 Mn
Dec 31, 2024 -76.20 Mn
Sep 30, 2024 -81.40 Mn
Jun 30, 2024 -57.42 Mn
Mar 31, 2024 -45.83 Mn
Dec 31, 2023 -36.95 Mn
Sep 30, 2023 -33.42 Mn
Jun 30, 2023 -30.33 Mn
Mar 31, 2023 -25.00 Mn
Dec 31, 2022 -25.75 Mn
Sep 30, 2022 -19.45 Mn
Jun 30, 2022 -18.58 Mn
Mar 31, 2022 -18.34 Mn
Dec 31, 2021 -17.49 Mn
Sep 30, 2021 -12.45 Mn
Jun 30, 2021 -9.84 Mn