Monopar Therapeutics (MNPR) EBITDA (2017 - 2025)
Monopar Therapeutics' (MNPR) quarterly EBITDA came in at -$3.5 million in Q3 2025, down 164.71% year-on-year from $5.4 million in Q3 2024, and down 48.82% quarter-over-quarter from -$2.4 million in Q2 2025.
Monopar Therapeutics (MNPR) EBITDA (2017 - 2025) Analysis & Trends
Monopar Therapeutics has disclosed EBITDA across 9 years of filings, most recently posting -$3.5 million for Q3 2025.
- EBITDA for Q3 2025 came in at -$3.5 million, down 164.71% year-over-year; the trailing twelve-month figure through Sep 2025 was -$9.8 million (down 48.22% YoY), and the FY2024 annual result was -$15.6 million, down 419.13% from the prior year.
- EBITDA came in at -$3.5 million for Q3 2025 at Monopar Therapeutics, down from -$2.4 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$57.0 in Q2 2021 to a low of -$3.5 million in Q3 2025.
- The 5-year median for EBITDA is -$2.4 million (2025), against an average of -$2.0 million.
- Across the five-year window, EBITDA jumped 100.0% in 2021 and sank 4809936.84% in 2022, its largest moves.
- Monopar Therapeutics' EBITDA stood at -$2.7 million in 2021, then decreased by 9.4% to -$2.9 million in 2022, then soared by 33.22% to -$2.0 million in 2023, then jumped by 32.37% to -$1.3 million in 2024, then tumbled by 164.71% to -$3.5 million in 2025.
- The last three EBITDA figures came in at -$3.5 million (Q3 2025), -$2.4 million (Q2 2025), and -$2.6 million (Q1 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -65.83 Mn |
| 10 | Monopar Therapeutics | 441.25 Mn | 441.25 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Sep 30, 2025 | -3.50 Mn |
| Jun 30, 2025 | -2.35 Mn |
| Mar 31, 2025 | -2.62 Mn |
| Sep 30, 2024 | -1.32 Mn |
| Jun 30, 2024 | -1.71 Mn |
| Mar 31, 2024 | -1.62 Mn |
| Sep 30, 2023 | -1.96 Mn |
| Jun 30, 2023 | -2.22 Mn |
| Mar 31, 2023 | -2.41 Mn |
| Dec 31, 2022 | -2.93 Mn |
| Sep 30, 2022 | -2.37 Mn |
| Jun 30, 2022 | -2.74 Mn |
| Mar 31, 2022 | -584.00 |
| Dec 31, 2021 | -2.68 Mn |
| Sep 30, 2021 | -2.46 Mn |
| Jun 30, 2021 | -57.00 |
| Mar 31, 2021 | -1.88 Mn |
| Dec 31, 2020 | -2.13 Mn |
| Sep 30, 2020 | -1.64 Mn |
| Jun 30, 2020 | -1.44 Mn |