Monopar Therapeutics (MNPR) EBITDA (2017 - 2025)

Monopar Therapeutics (MNPR) reported EBITDA of -$4.1 million for Q3 2025, down 159.89% on a YoY basis from $6.8 million in Q3 2024, and down 26.55% sequentially from -$3.2 million in Q2 2025.

Monopar Therapeutics (MNPR) EBITDA (2017 - 2025) Analysis & Trends

Monopar Therapeutics (MNPR) has 9 years of EBITDA data on file, last reported at -$4.1 million in Q3 2025.

  • For the quarter ending Q3 2025, EBITDA fell 159.89% year-over-year to -$4.1 million; the trailing twelve-month figure through Sep 2025 stood at -$12.1 million (down 69.49% YoY), and the FY2025 full-year result was $8.5 million, up 258.12% from the prior year.
  • EBITDA retreated to -$4.1 million in Q3 2025, from -$3.2 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$1.6 million in Q3 2024 to a low of -$4.1 million in Q3 2025.
  • A 5-year average of -$2.5 million and a median of -$2.5 million in 2022 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA surged 31.75% in 2024 and slumped 159.89% in 2025, its largest moves.
  • Tracing MNPR's EBITDA over 5 years: stood at -$2.7 million in 2021, then slipped by 8.5% to -$2.9 million in 2022, then gained by 28.98% to -$2.1 million in 2023, then gained by 23.77% to -$1.6 million in 2024, then tumbled by 159.89% to -$4.1 million in 2025.
  • Business Quant data shows MNPR's EBITDA at -$4.1 million in Q3 2025, -$3.2 million in Q2 2025, and -$3.2 million in Q1 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Monopar Therapeutics 800.03 Mn 738.20 Mn - -

Historic Data

Download Data
DateValue
Sep 30, 2025 -4.09 Mn
Jun 30, 2025 -3.23 Mn
Mar 31, 2025 -3.22 Mn
Sep 30, 2024 -1.57 Mn
Jun 30, 2024 -1.79 Mn
Mar 31, 2024 -1.72 Mn
Sep 30, 2023 -2.07 Mn
Jun 30, 2023 -2.33 Mn
Mar 31, 2023 -2.53 Mn
Dec 31, 2022 -2.91 Mn
Sep 30, 2022 -2.41 Mn
Jun 30, 2022 -2.76 Mn
Mar 31, 2022 -2.46 Mn
Dec 31, 2021 -2.68 Mn
Sep 30, 2021 -2.46 Mn
Jun 30, 2021 -2.09 Mn
Mar 31, 2021 -1.89 Mn
Dec 31, 2020 -2.26 Mn
Sep 30, 2020 -1.65 Mn
Jun 30, 2020 -1.46 Mn