Monopar Therapeutics (MNPR) EBITDA (2017 - 2025)

Monopar Therapeutics' (MNPR) quarterly EBITDA came in at -$3.5 million in Q3 2025, down 164.71% year-on-year from $5.4 million in Q3 2024, and down 48.82% quarter-over-quarter from -$2.4 million in Q2 2025.

Monopar Therapeutics (MNPR) EBITDA (2017 - 2025) Analysis & Trends

Monopar Therapeutics has disclosed EBITDA across 9 years of filings, most recently posting -$3.5 million for Q3 2025.

  • EBITDA for Q3 2025 came in at -$3.5 million, down 164.71% year-over-year; the trailing twelve-month figure through Sep 2025 was -$9.8 million (down 48.22% YoY), and the FY2024 annual result was -$15.6 million, down 419.13% from the prior year.
  • EBITDA came in at -$3.5 million for Q3 2025 at Monopar Therapeutics, down from -$2.4 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$57.0 in Q2 2021 to a low of -$3.5 million in Q3 2025.
  • The 5-year median for EBITDA is -$2.4 million (2025), against an average of -$2.0 million.
  • Across the five-year window, EBITDA jumped 100.0% in 2021 and sank 4809936.84% in 2022, its largest moves.
  • Monopar Therapeutics' EBITDA stood at -$2.7 million in 2021, then decreased by 9.4% to -$2.9 million in 2022, then soared by 33.22% to -$2.0 million in 2023, then jumped by 32.37% to -$1.3 million in 2024, then tumbled by 164.71% to -$3.5 million in 2025.
  • The last three EBITDA figures came in at -$3.5 million (Q3 2025), -$2.4 million (Q2 2025), and -$2.6 million (Q1 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -13.63 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -14.44 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 Monopar Therapeutics 441.25 Mn 441.25 Mn - -

Historic Data

Download Data
DateValue
Sep 30, 2025 -3.50 Mn
Jun 30, 2025 -2.35 Mn
Mar 31, 2025 -2.62 Mn
Sep 30, 2024 -1.32 Mn
Jun 30, 2024 -1.71 Mn
Mar 31, 2024 -1.62 Mn
Sep 30, 2023 -1.96 Mn
Jun 30, 2023 -2.22 Mn
Mar 31, 2023 -2.41 Mn
Dec 31, 2022 -2.93 Mn
Sep 30, 2022 -2.37 Mn
Jun 30, 2022 -2.74 Mn
Mar 31, 2022 -584.00
Dec 31, 2021 -2.68 Mn
Sep 30, 2021 -2.46 Mn
Jun 30, 2021 -57.00
Mar 31, 2021 -1.88 Mn
Dec 31, 2020 -2.13 Mn
Sep 30, 2020 -1.64 Mn
Jun 30, 2020 -1.44 Mn