Monopar Therapeutics (MNPR) Institutional Ownership

Institutions by Trading Activity

4,909,522Shares Outstanding

5,706Shares held by institutions

$329,522Value of institutional holdings

6.31%Institutional ownership %

39.62%Shares Changed QoQ

8No. of institutional investors

The institutional landscape for Monopar Therapeutics (NASDAQ:MNPR) includes 8 filers as of the latest reporting cycle ending December 2025.

Monopar Therapeutics saw its institutional ownership percentage fell to 6.3% in December 2025 from 88.3% in September 2025.
In percentage terms, this reflects as a holdings change of 39.62% quarter on quarter, and a decrease of 55.56% year over year.
A review of institutional activity for Monopar Therapeutics shows 4 of 8 filers increasing their positions, while 1 reduced their stake, and 3 remained unchanged.
The aggregate institutional position in Monopar Therapeutics now stands at 310.03K shares as of December 2025, after investors increased their holdings (up by 87.98K shares quarter on quarter which is down 2.27Mn shares year over year).
VANGUARD GROUP INC's holding of 293.82K shares as of December 31, 2025 makes it the primary institutional investor in Monopar Therapeutics, owning 5.98% of the stock.
Among the most significant buyers of Monopar Therapeutics during December 2025 were VANGUARD GROUP INC (85.60K), MOUNTAIN PACIFIC INVESTMENT ADVISERS LLC (6.10K), AMALGAMATED BANK (5), GAMMA Investing LLC (3).
Leading sellers of Monopar Therapeutics stock in December 2025 included UBS Group AG (3.72K).
The top 8 institutional holders of Monopar Therapeutics for the quarter ending December 2025 included VANGUARD GROUP INC (293.82K), MOUNTAIN PACIFIC INVESTMENT ADVISERS LLC (6.10K), GERBER, LLC (5.60K), UBS Group AG (4.25K), AMALGAMATED BANK (144), Allworth Financial LP (100), GAMMA Investing LLC (14), CWM, LLC (5).

5,706 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
JANUS HENDERSON GROUP PLC	30 Sep, 2025	1,287,368	115,000	9.81%	$105,313,139.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	30 Sep, 2025	659,195	60,000	10.01%	$53,836,456.00
RA CAPITAL MANAGEMENT, L.P.	30 Sep, 2025	511,207	0	0.00%	$41,750,276.00
WELLINGTON MANAGEMENT GROUP LLP	30 Sep, 2025	231,463	231,463	0.00%	$18,903,584.00
VANGUARD GROUP INC	30 Sep, 2025	208,218	121,729	140.75%	$17,005,165.00
BlackRock, Inc.	30 Sep, 2025	203,751	-1,418	-0.69%	$16,640,345.00
DEERFIELD MANAGEMENT COMPANY, L.P.	30 Sep, 2025	159,765	159,765	0.00%	$13,048,008.00
Saturn V Capital Management LP	30 Sep, 2025	155,370	155,370	0.00%	$12,689,068.00
TCG Crossover Management, LLC	30 Sep, 2025	153,000	153,000	0.00%	$12,495,510.00
ADAR1 Capital Management, LLC	30 Sep, 2025	129,999	29,025	28.75%	$10,617,018.00
Vivo Capital, LLC	30 Sep, 2025	90,500	90,500	0.00%	$7,391,135.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	84,961	-11,958	-12.34%	$6,940,459.00
Affinity Asset Advisors, LLC	30 Sep, 2025	79,483	11,983	17.75%	$6,491,377.00
STATE STREET CORP	30 Sep, 2025	72,238	30,412	72.71%	$5,899,677.00
DRIEHAUS CAPITAL MANAGEMENT LLC	30 Sep, 2025	64,636	64,636	0.00%	$5,278,822.00
Ally Bridge Group (NY) LLC	30 Sep, 2025	64,455	29,918	86.63%	$5,264,040.00
NORTHERN TRUST CORP	30 Sep, 2025	26,855	-4,958	-15.58%	$2,193,247.00
Bank of New York Mellon Corp	30 Sep, 2025	17,170	8,222	91.89%	$1,402,260.00
MORGAN STANLEY	30 Sep, 2025	15,711	7,779	98.07%	$1,283,118.00
BARCLAYS PLC	30 Sep, 2025	15,082	7,797	107.03%	$1,231,747.00

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