Mirum Pharmaceuticals (MIRM) Gross Margin (2021 - 2026)
Mirum Pharmaceuticals (MIRM) posted quarterly Gross Margin of 81.98% for Q1 2026, up 261.0% year-over-year from 22.71% in Q1 2025, and up 1.19% quarter-over-quarter from 81.02% in Q4 2025.
Mirum Pharmaceuticals (MIRM) Gross Margin (2021 - 2026) Analysis & Trends
Mirum Pharmaceuticals' Gross Margin history runs 6 years deep, the most recent figure standing at 81.98% for Q1 2026.
- In Q1 2026, Gross Margin rose 261.0% year-over-year to 81.98%; the TTM figure through Mar 2026 stood at 81.39% (up 428.0% YoY), while the FY2025 annual figure was 80.77%, up 501.0% from the prior year.
- Gross Margin for Q1 2026 stood at 81.98%, up from 81.02% in the prior quarter.
- The five-year high for Gross Margin was 85.56% in Q2 2022, with the low at 64.03% in Q4 2023.
- The 5-year median for Gross Margin is 81.02% (2025), against an average of 79.46%.
- The sharpest annual moves came in 2022 and 2023: Gross Margin soared 4454 bps in 2022, then sank 1987 bps in 2023.
- Mirum Pharmaceuticals' Gross Margin stood at 83.9% in 2022, then slipped by 24 bps to 64.03% in 2023, then rose by 20 bps to 77.09% in 2024, then grew by 5 bps to 81.02% in 2025, then advanced by 1 bps to 81.98% in 2026.
- Business Quant data shows MIRM's Gross Margin at 81.98% in Q1 2026, 81.02% in Q4 2025, and 80.8% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 90.68% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 89.76% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 60,631,834.75% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | - |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 76.90% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 84.20% |
| 10 | Mirum Pharmaceuticals | 6.52 Bn | 6.08 Bn | 145.90 Mn | 82.78% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 82.78% |
| Mar 31, 2026 | 81.98% |
| Dec 31, 2025 | 81.02% |
| Sep 30, 2025 | 80.80% |
| Jun 30, 2025 | 81.67% |
| Mar 31, 2025 | 79.37% |
| Dec 31, 2024 | 77.09% |
| Sep 30, 2024 | 76.98% |
| Jun 30, 2024 | 74.03% |
| Mar 31, 2024 | 74.24% |
| Dec 31, 2023 | 64.03% |
| Sep 30, 2023 | 78.57% |
| Jun 30, 2023 | 81.83% |
| Mar 31, 2023 | 84.24% |
| Dec 31, 2022 | 83.90% |
| Sep 30, 2022 | 84.39% |
| Jun 30, 2022 | 85.56% |
| Mar 31, 2022 | 81.20% |
| Dec 31, 2021 | 39.36% |
| Sep 30, 2021 | 100.00% |