Growth Metrics

Mirum Pharmaceuticals (MIRM) Gross Margin (2023 - 2026)

Mirum Pharmaceuticals' quarterly Gross Margin came in at 81.98% in Q1 2026, up 261.0% year-on-year from 22.71% in Q1 2025, and up 1.19% quarter-over-quarter from 81.02% in Q4 2025.

Mirum Pharmaceuticals has reported Gross Margin for 4 years, with the latest figure at 81.98% in Q1 2026.

  • For the quarter ending Q1 2026, Gross Margin rose 261.0% year-over-year to 81.98%; the trailing twelve-month figure through Mar 2026 stood at 81.39% (up 428.0% YoY), and the FY2025 full-year result was 80.77%, up 501.0% from the prior year.
  • Gross Margin for Q1 2026 stood at 81.98%, up from 81.02% in the prior quarter.
  • The five-year high for Gross Margin was 84.24% in Q1 2023, with the low at 64.03% in Q4 2023.
  • Average Gross Margin over 4 years is 78.14%, with a median of 79.37% recorded in 2025.
  • Peak annual rise in Gross Margin reached 1306 bps in 2024, while the deepest fall reached 1000 bps in 2024.
  • Tracing MIRM's Gross Margin over 4 years: stood at 64.03% in 2023, then advanced by 20 bps to 77.09% in 2024, then rose by 5 bps to 81.02% in 2025, then grew by 1 bps to 81.98% in 2026.
  • The last three Gross Margin figures came in at 81.98% (Q1 2026), 81.02% (Q4 2025), and 80.8% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 79.04%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 86.85%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 91.79%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 82.22%
10 Mirum Pharmaceuticals 5.97 Bn 5.59 Bn 131.08 Mn 81.98%

Historic Data

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DateValue
Mar 31, 2026 81.98%
Dec 31, 2025 81.02%
Sep 30, 2025 80.80%
Jun 30, 2025 81.67%
Mar 31, 2025 79.37%
Dec 31, 2024 77.09%
Sep 30, 2024 76.98%
Jun 30, 2024 74.03%
Mar 31, 2024 74.24%
Dec 31, 2023 64.03%
Sep 30, 2023 78.57%
Jun 30, 2023 81.83%
Mar 31, 2023 84.24%