Mirum Pharmaceuticals, Inc. (MIRM) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

48,166,279Shares Outstanding

12,088,656Shares held by institutions

$1,243,076,496Value of institutional holdings

122.78%Institutional ownership %

9.04%Shares Changed QoQ

274No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) includes 274 filers as of the latest reporting cycle ending December 2025.

Institutional ownership in Mirum Pharmaceuticals edged up to 122.8% in December 2025, compared to 119.3% in September 2025.
In percentage terms, this reflects as a holdings change of 9.04% quarter on quarter, and an increase of 33.66% year over year.
Of these 274 institutional investors, 159 increased their holdings in Mirum Pharmaceuticals, while 76 of them reduced positions, and 39 investors maintained their exposure.
The aggregate institutional position in Mirum Pharmaceuticals now stands at 59.14Mn shares as of December 2025, after investors increased their holdings (up by 4.90Mn shares quarter on quarter which is up 6.09Mn shares year over year).
Frazier Life Sciences Management, L.P. continues to be the largest institutional holder of Mirum Pharmaceuticals as of December 31, 2025, with a position of 6.80Mn shares, representing 14.11% of the company's outstanding stock.
Among the most significant buyers of Mirum Pharmaceuticals during December 2025 were JANUS HENDERSON GROUP PLC (1.07Mn), STATE STREET CORP (797.09K), WELLINGTON MANAGEMENT GROUP LLP (447.14K), Soleus Capital Management, L.P. (424.92K), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (421.85K).
Leading sellers of Mirum Pharmaceuticals stock in December 2025 included Point72 Asset Management, L.P. (600.04K), EVENTIDE ASSET MANAGEMENT, LLC (428.98K), JANE STREET GROUP, LLC (336.49K), MORGAN STANLEY (244.46K), ARROWSTREET CAPITAL, LIMITED PARTNERSHIP (239.81K).
The top 10 institutional holders of Mirum Pharmaceuticals for the quarter ending December 2025 included Frazier Life Sciences Management, L.P. (6.80Mn), JANUS HENDERSON GROUP PLC (6.07Mn), BlackRock, Inc. (3.65Mn), VANGUARD GROUP INC (2.60Mn), STATE STREET CORP (2.14Mn), EVENTIDE ASSET MANAGEMENT, LLC (2.09Mn), BVF INC/IL (1.50Mn), Novo Holdings A/S (1.26Mn), WELLINGTON MANAGEMENT GROUP LLP (1.24Mn), TANG CAPITAL MANAGEMENT LLC (1.24Mn).

274 Institutional Holders

12,088,656 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Frazier Life Sciences Management, L.P.	31 Dec, 2025	6,795,121	0	0.00%	$536,746,608.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	6,065,308	1,067,722	21.36%	$479,050,121.00
BlackRock, Inc.	31 Dec, 2025	3,645,286	42,852	1.19%	$287,941,139.00
VANGUARD GROUP INC	31 Dec, 2025	2,596,089	50,720	1.99%	$205,065,069.00
STATE STREET CORP	31 Dec, 2025	2,143,992	797,088	59.18%	$169,353,928.00
EVENTIDE ASSET MANAGEMENT, LLC	31 Dec, 2025	2,093,582	-428,981	-17.01%	$165,370,112.00
BVF INC/IL	31 Dec, 2025	1,495,290	0	0.00%	$118,112,957.00
Novo Holdings A/S	31 Dec, 2025	1,264,028	0	0.00%	$99,845,572.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	1,237,830	447,141	56.55%	$97,776,191.00
TANG CAPITAL MANAGEMENT LLC	31 Dec, 2025	1,236,027	0	0.00%	$97,633,773.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,062,926	52,904	5.24%	$83,975,140.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	948,161	24,652	2.67%	$74,895,237.00
Clearbridge Investments, LLC	31 Dec, 2025	865,967	-137,836	-13.73%	$68,402,733.00
CITADEL ADVISORS LLC	31 Dec, 2025	840,220	-200,324	-19.25%	$66,368,978.00
Polar Capital Holdings Plc	31 Dec, 2025	793,642	-26,910	-3.28%	$62,689,782.00
Rock Springs Capital Management LP	31 Dec, 2025	762,294	1,168	0.15%	$60,213,603.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	724,317	273,479	60.66%	$57,213,800.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	713,452	322,978	82.71%	$56,355,574.00
BNP PARIBAS FINANCIAL MARKETS	31 Dec, 2025	655,778	54,705	9.10%	$51,799,904.00
FRANKLIN RESOURCES INC	31 Dec, 2025	650,715	49,578	8.25%	$51,399,978.00

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