Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026)
Madrigal Pharmaceuticals (MDGL) posted quarterly Operating Expenses of $420.6 million for Q2 2026, up 61.75% year-over-year from $260.0 million in Q2 2025, and up 4.08% quarter-over-quarter from $404.1 million in Q1 2026.
Analysis
Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026) Analysis & Trends
Madrigal Pharmaceuticals (MDGL) has reported Operating Expenses for 17 consecutive years, with $420.6 million the latest figure, recorded in Q2 2026.
- In Q2 2026, Operating Expenses rose 61.75% year-over-year to $420.6 million; the TTM figure through Jun 2026 stood at $1.6 billion (up 94.65% YoY), while the FY2025 annual figure was $1.3 billion, up 85.62% from the prior year.
- Operating Expenses advanced to $420.6 million in Q2 2026 per MDGL's latest filing, from $404.1 million in the prior quarter.
- Across five years, Operating Expenses topped out at $420.6 million in Q2 2026 and bottomed at $57.6 million in Q1 2022.
- Historically, Operating Expenses has averaged $190.8 million across 5 years, with a median of $161.2 million in 2024.
- Annual changes were most pronounced in 2022 — Operating Expenses increased 8.7% — and 2025, when it surged 124.81%.
- Madrigal Pharmaceuticals' Operating Expenses stood at $85.3 million in 2022, then surged by 37.37% to $117.2 million in 2023, then soared by 45.35% to $170.3 million in 2024, then surged by 123.52% to $380.7 million in 2025, then climbed by 10.47% to $420.6 million in 2026.
- Business Quant data shows MDGL's Operating Expenses at $420.6 million in Q2 2026, $404.1 million in Q1 2026, and $380.7 million in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.62 Bn | 131.77 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 85.73 Bn | 77.73 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 63.53 Bn | 58.35 Bn | 1.37 Bn | -1.05 Bn |
| 4 | Moderna | 58.23 Bn | 53.09 Bn | 52.00 Mn | 960.00 Mn |
| 5 | Revolution Medicines | 44.05 Bn | 44.05 Bn | - | 505.13 Mn |
| 6 | BeOne Medicines | 40.03 Bn | 34.93 Bn | 1.53 Bn | 1.21 Bn |
| 7 | Alnylam Pharmaceuticals | 35.50 Bn | 32.19 Bn | 992.69 Mn | 1.06 Bn |
| 8 | Royalty Pharma | 28.52 Bn | 27.68 Bn | - | 541.02 Mn |
| 9 | Insmed | 27.46 Bn | 26.30 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Madrigal Pharmaceuticals | 15.96 Bn | 15.12 Bn | - | 420.56 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 420.56 Mn |
| Mar 31, 2026 | 404.06 Mn |
| Dec 31, 2025 | 380.69 Mn |
| Sep 30, 2025 | 401.24 Mn |
| Jun 30, 2025 | 260.00 Mn |
| Mar 31, 2025 | 216.56 Mn |
| Dec 31, 2024 | 170.32 Mn |
| Sep 30, 2024 | 178.48 Mn |
| Jun 30, 2024 | 177.18 Mn |
| Mar 31, 2024 | 152.04 Mn |
| Dec 31, 2023 | 117.18 Mn |
| Sep 30, 2023 | 98.53 Mn |
| Jun 30, 2023 | 86.45 Mn |
| Mar 31, 2023 | 78.34 Mn |
| Dec 31, 2022 | 85.30 Mn |
| Sep 30, 2022 | 80.41 Mn |
| Jun 30, 2022 | 70.27 Mn |
| Mar 31, 2022 | 57.59 Mn |
| Dec 31, 2021 | 64.60 Mn |
| Sep 30, 2021 | 63.16 Mn |