Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026)
Madrigal Pharmaceuticals (MDGL) reported Operating Expenses of $26.8 million for Q1 2026, up 494.88% year-over-year from $4.5 million in Q1 2025, and down 92.95% quarter-over-quarter from $380.7 million in Q4 2025.
Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026) Analysis & Trends
Madrigal Pharmaceuticals (MDGL) has 17 years of Operating Expenses data on file, last reported at $26.8 million in Q1 2026.
- Operating Expenses for Q1 2026 came in at $26.8 million, up 494.88% year-over-year; the trailing twelve-month figure through Mar 2026 was $817.8 million (up 19.83% YoY), and the FY2025 annual result was $1.3 billion, up 85.62% from the prior year.
- Operating Expenses slipped to $26.8 million in Q1 2026 per MDGL's latest filing, from $380.7 million in the prior quarter.
- Over five years, Operating Expenses peaked at $675.2 million in Q4 2024 and troughed at $636000.0 in Q2 2024.
- A 5-year average of $139.2 million and a median of $79.4 million in 2022 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2024 and 2025: Operating Expenses tumbled 99.26% in 2024, then soared 18545.12% in 2025.
- A 5-year view of Operating Expenses shows it stood at $85.3 million in 2022, then jumped by 37.37% to $117.2 million in 2023, then jumped by 476.24% to $675.2 million in 2024, then plunged by 43.62% to $380.7 million in 2025, then sank by 92.95% to $26.8 million in 2026.
- Business Quant data shows MDGL's Operating Expenses at $26.8 million in Q1 2026, $380.7 million in Q4 2025, and $401.2 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -67.40 Mn |
| 10 | Madrigal Pharmaceuticals | 14.67 Bn | 14.44 Bn | - | 26.85 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 26.85 Mn |
| Dec 31, 2025 | 380.69 Mn |
| Sep 30, 2025 | 401.24 Mn |
| Jun 30, 2025 | 9.07 Mn |
| Mar 31, 2025 | 4.51 Mn |
| Dec 31, 2024 | 675.22 Mn |
| Sep 30, 2024 | 2.15 Mn |
| Jun 30, 2024 | 636,000.00 |
| Mar 31, 2024 | 152.04 Mn |
| Dec 31, 2023 | 117.18 Mn |
| Jun 30, 2023 | 86.45 Mn |
| Mar 31, 2023 | 78.34 Mn |
| Dec 31, 2022 | 85.30 Mn |
| Sep 30, 2022 | 80.41 Mn |
| Jun 30, 2022 | 70.27 Mn |
| Mar 31, 2022 | 57.59 Mn |
| Dec 31, 2021 | 64.60 Mn |
| Sep 30, 2021 | 63.16 Mn |
| Jun 30, 2021 | 61.74 Mn |
| Mar 31, 2021 | 52.98 Mn |