Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026)

Madrigal Pharmaceuticals' (MDGL) quarterly Operating Expenses came in at $404.1 million in Q1 2026, up 86.58% year-on-year from $216.6 million in Q1 2025, and down 67.06% on a QoQ basis from $1.2 billion in Q4 2025.

Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026) Analysis & Trends

Madrigal Pharmaceuticals (MDGL) has 17 years of Operating Expenses data on file, last reported at $404.1 million in Q1 2026.

  • On a quarterly basis, Operating Expenses rose 86.58% year-over-year to $404.1 million in Q1 2026; TTM through Mar 2026 was $2.0 billion, a 823.54% increase from a year earlier, with the FY2025 full-year figure at $1.3 billion, up 20090.92% from the prior year.
  • Operating Expenses for Q1 2026 stood at $404.1 million, down from $1.2 billion in the prior quarter.
  • Over the last five years, Operating Expenses for MDGL reached as high as $1.2 billion in Q4 2025 and fell as low as -$501.5 million in Q4 2024.
  • Historically, Operating Expenses has averaged $152.1 million across 5 years, with a median of $82.9 million in 2022.
  • Across the five-year window, Operating Expenses tumbled 527.95% in 2024 and jumped 18545.12% in 2025, its largest moves.
  • Year by year, Operating Expenses stood at $85.3 million in 2022, then jumped by 37.37% to $117.2 million in 2023, then tumbled by 527.95% to -$501.5 million in 2024, then surged by 344.65% to $1.2 billion in 2025, then slumped by 67.06% to $404.1 million in 2026.
  • Per Business Quant data, the three most recent Operating Expenses figures were $404.1 million in Q1 2026, $1.2 billion in Q4 2025, and $401.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Madrigal Pharmaceuticals 15.79 Bn 15.56 Bn - 404.06 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 404.06 Mn
Dec 31, 2025 1.23 Bn
Sep 30, 2025 401.24 Mn
Jun 30, 2025 9.07 Mn
Mar 31, 2025 216.56 Mn
Dec 31, 2024 -501.46 Mn
Sep 30, 2024 2.15 Mn
Jun 30, 2024 636,000.00
Dec 31, 2023 117.18 Mn
Sep 30, 2023 98.53 Mn
Jun 30, 2023 86.45 Mn
Mar 31, 2023 78.34 Mn
Dec 31, 2022 85.30 Mn
Sep 30, 2022 80.41 Mn
Jun 30, 2022 70.27 Mn
Mar 31, 2022 57.59 Mn
Dec 31, 2021 64.60 Mn
Sep 30, 2021 63.16 Mn
Jun 30, 2021 61.74 Mn
Mar 31, 2021 52.98 Mn