Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026)
Madrigal Pharmaceuticals' (MDGL) quarterly Operating Expenses came in at $404.1 million in Q1 2026, up 86.58% year-on-year from $216.6 million in Q1 2025, and down 67.06% on a QoQ basis from $1.2 billion in Q4 2025.
Madrigal Pharmaceuticals (MDGL) Operating Expenses (2010 - 2026) Analysis & Trends
Madrigal Pharmaceuticals (MDGL) has 17 years of Operating Expenses data on file, last reported at $404.1 million in Q1 2026.
- On a quarterly basis, Operating Expenses rose 86.58% year-over-year to $404.1 million in Q1 2026; TTM through Mar 2026 was $2.0 billion, a 823.54% increase from a year earlier, with the FY2025 full-year figure at $1.3 billion, up 20090.92% from the prior year.
- Operating Expenses for Q1 2026 stood at $404.1 million, down from $1.2 billion in the prior quarter.
- Over the last five years, Operating Expenses for MDGL reached as high as $1.2 billion in Q4 2025 and fell as low as -$501.5 million in Q4 2024.
- Historically, Operating Expenses has averaged $152.1 million across 5 years, with a median of $82.9 million in 2022.
- Across the five-year window, Operating Expenses tumbled 527.95% in 2024 and jumped 18545.12% in 2025, its largest moves.
- Year by year, Operating Expenses stood at $85.3 million in 2022, then jumped by 37.37% to $117.2 million in 2023, then tumbled by 527.95% to -$501.5 million in 2024, then surged by 344.65% to $1.2 billion in 2025, then slumped by 67.06% to $404.1 million in 2026.
- Per Business Quant data, the three most recent Operating Expenses figures were $404.1 million in Q1 2026, $1.2 billion in Q4 2025, and $401.2 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | Madrigal Pharmaceuticals | 15.79 Bn | 15.56 Bn | - | 404.06 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 404.06 Mn |
| Dec 31, 2025 | 1.23 Bn |
| Sep 30, 2025 | 401.24 Mn |
| Jun 30, 2025 | 9.07 Mn |
| Mar 31, 2025 | 216.56 Mn |
| Dec 31, 2024 | -501.46 Mn |
| Sep 30, 2024 | 2.15 Mn |
| Jun 30, 2024 | 636,000.00 |
| Dec 31, 2023 | 117.18 Mn |
| Sep 30, 2023 | 98.53 Mn |
| Jun 30, 2023 | 86.45 Mn |
| Mar 31, 2023 | 78.34 Mn |
| Dec 31, 2022 | 85.30 Mn |
| Sep 30, 2022 | 80.41 Mn |
| Jun 30, 2022 | 70.27 Mn |
| Mar 31, 2022 | 57.59 Mn |
| Dec 31, 2021 | 64.60 Mn |
| Sep 30, 2021 | 63.16 Mn |
| Jun 30, 2021 | 61.74 Mn |
| Mar 31, 2021 | 52.98 Mn |