Lexicon Pharmaceuticals (LXRX) Return on Sales (2010 - 2026)

Lexicon Pharmaceuticals (LXRX) posted quarterly Return on Sales of 0.0% for Q1 2026, up 22.0% year-over-year from 0.0% in Q1 2025, and up 91.8% quarter-over-quarter from 0.03% in Q4 2025.

Lexicon Pharmaceuticals (LXRX) Return on Sales (2010 - 2026) Analysis & Trends

Lexicon Pharmaceuticals (LXRX) has reported Return on Sales for 17 consecutive years, with 0.0% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Sales rose 22.0% year-over-year to 0.0%; the TTM figure through Mar 2026 stood at 0.01% (up 6.0% YoY), while the FY2025 annual figure was 0.01%, up 19.0% from the prior year.
  • Return on Sales rose to 0.0% in Q1 2026 per LXRX's latest filing, from 0.03% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.0% in Q2 2025 and bottomed at 31.11% in Q1 2023.
  • Historically, Return on Sales has averaged 6.44% across 5 years, with a median of 0.43% in 2024.
  • Annual changes were most pronounced in 2022 — Return on Sales slumped 2499 bps — and 2024, when it jumped 3065 bps.
  • Lexicon Pharmaceuticals' Return on Sales stood at 28.49% in 2022, then jumped by 98 bps to 0.69% in 2023, then soared by 98 bps to 0.01% in 2024, then sank by 122 bps to 0.03% in 2025, then surged by 92 bps to 0.0% in 2026.
  • Business Quant data shows LXRX's Return on Sales at 0.0% in Q1 2026, 0.03% in Q4 2025, and 0.01% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Lexicon Pharmaceuticals 1.04 Bn 846.13 Mn 653,000.00 -0.54%

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.54%
Mar 31, 2026 0.00%
Dec 31, 2025 -0.03%
Sep 30, 2025 -0.01%
Jun 30, 2025 0.00%
Mar 31, 2025 -0.23%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.39%
Jun 30, 2024 -0.35%
Mar 31, 2024 -0.46%
Dec 31, 2023 -0.69%
Sep 30, 2023 -3.70%
Jun 30, 2023 -1.77%
Mar 31, 2023 -31.11%
Dec 31, 2022 -28.49%
Sep 30, 2022 -28.40%
Jun 30, 2022 -7.47%
Sep 30, 2021 -3.41%
Jun 30, 2021 1.91%
Mar 31, 2021 -0.63%