Lexicon Pharmaceuticals LXRX Institutional Ownership

NASDAQ LXRX

$2.23 -0.03 (-1.11%)

As of: Sep 4, 2026 · 2:33 PM EDT

Institutions by Trading Activity

150 Institutions

Increased 83 55.3%

Unchanged 31 20.7%

Reduced 36 24.0%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

83.78%

▲+2.99 pp QoQ

Shares Held by Institutions

366.68Mn

of 437.65Mn outstanding

▲+16.26% QoQ

Shares Outstanding

437.65Mn

70.97Mn held outside 13F filers

Institutional Investors

150

filed 13F for Jun 2026

▲+13 vs prior quarter

Net Shares Added (QoQ)

+51.29Mn

accumulated since last quarter

Value of Holdings

$828.70Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Lexicon Pharmaceuticals, Inc. (NASDAQ:LXRX) has 150 institutional investors with active 13F positions as of June 2026.

They owned 83.8% of outstanding stock in June 2026, up from 80.8% the prior quarter.
Their total shares held in LXRX increased 16.26% quarter over quarter, and separately, investors owning Lexicon Pharmaceuticals increased 20.97% from a year ago.
Of these 150 funds, 83 grew their exposure to Lexicon Pharmaceuticals, 36 cut back, and 31 maintained positions.
In total, institutional investors held 366.68Mn shares in Lexicon Pharmaceuticals as of June 2026, up by 51.29Mn shares quarter on quarter, and up 109.51Mn shares year over year.
Artal Group S.A. leads ownership in LXRX with 175.16Mn shares as of June 30, 2026, equal to 40.02% of outstanding shares.
Leading buyers of Lexicon Pharmaceuticals shares for the quarter ending June 2026 were Artal Group S.A. (20.42Mn), BlackRock, Inc. (14.03Mn), FMR LLC (6.73Mn), State Street Corp (3.95Mn), GEODE CAPITAL MANAGEMENT, LLC (3.08Mn).
Top sellers of LXRX stock for the quarter ending June 2026 included MILLENNIUM MANAGEMENT LLC (3.81Mn), UBS Group AG (1.8Mn), CIBC Bancorp USA Inc. (1.79Mn), SUSQUEHANNA INTERNATIONAL GROUP, LLP (1.42Mn), Goldman Sachs Group Inc (584.97K).
Business Quant data shows the 10 biggest positions in Lexicon Pharmaceuticals as of June 2026 are held by Artal Group S.A. (175.16Mn), FMR LLC (51.78Mn), Siren, L.L.C. (44.3Mn), Sessa Capital IM, L.P. (18.96Mn), BlackRock, Inc. (17.35Mn), VANGUARD CAPITAL MANAGEMENT LLC (9.9Mn), Point72 Asset Management, L.P. (8.25Mn), GEODE CAPITAL MANAGEMENT, LLC (6.24Mn), State Street Corp (4.92Mn), VANGUARD PORTFOLIO MANAGEMENT LLC (2.36Mn).

Form 13F Holdings

150 Institutional Holders

Report period 30 Jun, 2026

Total shares held 366.68Mn

Of outstanding 83.78%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	Artal Group S.A.	0001053906	175,156,062	40.02%	▲20,421,735	+13.20%	$420.37Mn
2	FMR LLC	0000315066	51,782,045	11.83%	▲6,725,707	+14.93%	$124.28Mn
3	Siren, L.L.C.	0002005245	44,303,518	10.12%	0	0.00%	$106.33Mn
4	Sessa Capital IM, L.P.	0001595849	18,960,836	4.33%	▲1,047,875	+5.85%	$45.51Mn
5	BlackRock, Inc.	0002012383	17,348,741	3.96%	▲14,026,522	+422.20%	$41.64Mn
6	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	9,901,208	2.26%	▲382,041	+4.01%	$23.76Mn
7	Point72 Asset Management, L.P.	0001603466	8,251,325	1.89%	▲436,719	+5.59%	$19.80Mn
8	GEODE CAPITAL MANAGEMENT, LLC	0001214717	6,244,372	1.43%	▲3,075,261	+97.04%	$14.99Mn
9	State Street Corp	0000093751	4,917,769	1.12%	▲3,953,731	+410.12%	$11.80Mn
10	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	2,357,749	0.54%	▲1,811,149	+331.35%	$5.66Mn
11	Northern Trust Corp	0000073124	1,968,619	0.45%	▲1,473,953	+297.97%	$4.72Mn
12	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0000884546	1,956,775	0.45%	▲645,477	+49.22%	$4.70Mn
12	Sixth Street Partners Management Company, L.P.	0001812095	1,956,775	0.45%	▲1,956,775	0.00%	$4.70Mn
13	VANGUARD FIDUCIARY TRUST CO	0000933478	1,634,571	0.37%	▲302,287	+22.69%	$3.92Mn
14	CITADEL ADVISORS LLC	0001423053	1,601,182	0.37%	▲506,281	+46.24%	$3.84Mn
15	Ishara Investments LP	0002111609	1,271,000	0.29%	▲369,000	+40.91%	$3.05Mn
16	MILLENNIUM MANAGEMENT LLC	0001273087	1,134,229	0.26%	▼3,810,502	-77.06%	$2.72Mn
17	RENAISSANCE TECHNOLOGIES LLC	0001037389	1,127,000	0.26%	▼473,500	-29.58%	$2.70Mn
18	MACKENZIE FINANCIAL CORP	0000919859	963,354	0.22%	▲190,677	+24.68%	$2.31Mn
19	ADAR1 Capital Management, LLC	0001940272	750,000	0.17%	0	0.00%	$1.80Mn

Showing 1 to 20 of 150 holders