Lexicon Pharmaceuticals (LXRX) Return on Equity [ROE] (2009 - 2026)
Lexicon Pharmaceuticals (LXRX) recorded Return on Equity [ROE] of -28.88% in Q2 2026, up 64.89 percentage points from -93.77% a year earlier but down 13.27 percentage points from the prior quarter.
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Analysis
Lexicon Pharmaceuticals (LXRX) Return on Equity [ROE] (2009 - 2026) Analysis & Trends
For FY2025, Lexicon Pharmaceuticals reported Return on Equity [ROE] of -38.59%, up 126.32 percentage points from FY2024.
- Annual Return on Equity [ROE] has a five-year change of +4.25 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -164.91% in FY2024 (-1.52 pp), -163.39% in FY2023 (-73.64 pp), -89.75% in FY2022 (-24.74 pp) and -65.01% in FY2021 (-22.18 pp).
- Quarterly Return on Equity [ROE] has ranged from -154.27% in Q4 2023 to -15.61% in Q1 2026 over the past five years.
- On a year-over-year basis, Return on Equity [ROE] has increased for four consecutive quarters, with an average year-over-year change of +36.29 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 225.51 percentage points in Q3 2021, against a drop of 144.79 percentage points in Q2 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -15.61% (Q1 2026), -42.96% (Q4 2025) and -53.58% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 74.39% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | - |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 5.63% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 21.60% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 72.13% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -31.17% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 4.66% |
| 10 | Lexicon Pharmaceuticals | 831.26 Mn | 190.55 Mn | 11.17 Mn | -37.06% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -37.06% |
| Jun 30, 2026 | -32.49% |
| Mar 31, 2026 | -16.91% |
| Dec 31, 2025 | -44.30% |
| Sep 30, 2025 | -55.21% |
| Jun 30, 2025 | -95.41% |
| Mar 31, 2025 | -131.78% |
| Dec 31, 2024 | -123.48% |
| Sep 30, 2024 | -103.19% |
| Jun 30, 2024 | -76.47% |
| Mar 31, 2024 | -101.30% |
| Dec 31, 2023 | -151.89% |
| Sep 30, 2023 | -96.65% |
| Jun 30, 2023 | -95.24% |
| Mar 31, 2023 | -107.74% |
| Dec 31, 2022 | -78.40% |
| Sep 30, 2022 | -81,705.94% |
| Jun 30, 2022 | -107,346.97% |
| Mar 31, 2022 | -85,087.28% |
| Dec 31, 2021 | -70,154.04% |
API Access
Lexicon Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=LXRX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "LXRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=LXRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();