Lexicon Pharmaceuticals (LXRX) Return on Capital Employed (2011 - 2026)

Lexicon Pharmaceuticals (LXRX) reported Return on Capital Employed of 11.16% for Q1 2026, up 8356.0% year-over-year from 0.13% in Q1 2025, and up 60.15% quarter-over-quarter from 28.01% in Q4 2025.

Lexicon Pharmaceuticals (LXRX) Return on Capital Employed (2011 - 2026) Analysis & Trends

Lexicon Pharmaceuticals (LXRX) has 16 years of Return on Capital Employed data on file, last reported at 11.16% in Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 11.16%, up 8356.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 11.16% (up 8356.0% YoY), and the FY2025 annual result was 22.15%, up 6799.0% from the prior year.
  • Return on Capital Employed grew to 11.16% in Q1 2026 per LXRX's latest filing, from 28.01% in the prior quarter.
  • Over five years, Return on Capital Employed peaked at 11.16% in Q1 2026 and troughed at 94.72% in Q1 2025.
  • A 5-year average of 61.18% and a median of 62.0% in 2024 frame the typical range for Return on Capital Employed.
  • The sharpest annual moves came in 2022 and 2026: Return on Capital Employed slumped 11610 bps in 2022, then jumped 8356 bps in 2026.
  • A 5-year view of Return on Capital Employed shows it stood at 59.33% in 2022, then tumbled by 31 bps to 77.57% in 2023, then grew by 4 bps to 74.52% in 2024, then soared by 62 bps to 28.01% in 2025, then jumped by 60 bps to 11.16% in 2026.
  • Business Quant data shows LXRX's Return on Capital Employed at 11.16% in Q1 2026, 28.01% in Q4 2025, and 34.46% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Lexicon Pharmaceuticals 804.48 Mn 633.82 Mn 20.99 Mn -11.16%

Historic Data

Download Data
DateValue
Mar 31, 2026 -11.16%
Dec 31, 2025 -28.01%
Sep 30, 2025 -34.46%
Jun 30, 2025 -52.19%
Mar 31, 2025 -94.72%
Dec 31, 2024 -74.52%
Sep 30, 2024 -67.84%
Jun 30, 2024 -53.63%
Mar 31, 2024 -62.00%
Dec 31, 2023 -77.57%
Sep 30, 2023 -58.75%
Jun 30, 2023 -60.28%
Mar 31, 2023 -68.63%
Dec 31, 2022 -59.33%
Sep 30, 2022 -71.74%
Jun 30, 2022 -89.10%
Mar 31, 2022 -76.19%
Dec 31, 2021 -65.73%
Sep 30, 2021 -50.25%
Jun 30, 2021 27.01%