Lexicon Pharmaceuticals (LXRX) Return on Capital Employed (2011 - 2026)

Lexicon Pharmaceuticals' (LXRX) quarterly Return on Capital Employed came in at 11.16% in Q1 2026, up 8356.0% year-on-year from 0.13% in Q1 2025, and up 60.15% on a QoQ basis from 28.01% in Q4 2025.

Lexicon Pharmaceuticals (LXRX) Return on Capital Employed (2011 - 2026) Analysis & Trends

Lexicon Pharmaceuticals (LXRX) has 16 years of Return on Capital Employed data on file, last reported at 11.16% in Q1 2026.

  • On a quarterly basis, Return on Capital Employed rose 8356.0% year-over-year to 11.16% in Q1 2026; TTM through Mar 2026 was 11.16%, a 8356.0% increase from a year earlier, with the FY2025 full-year figure at 22.15%, up 6799.0% from the prior year.
  • Return on Capital Employed for Q1 2026 stood at 11.16%, up from 28.01% in the prior quarter.
  • Over the last five years, Return on Capital Employed for LXRX reached as high as 11.16% in Q1 2026 and fell as low as 94.72% in Q1 2025.
  • Historically, Return on Capital Employed has averaged 61.18% across 5 years, with a median of 62.0% in 2024.
  • Across the five-year window, Return on Capital Employed plunged 11610 bps in 2022 and surged 8356 bps in 2026, its largest moves.
  • Year by year, Return on Capital Employed stood at 59.33% in 2022, then plunged by 31 bps to 77.57% in 2023, then gained by 4 bps to 74.52% in 2024, then soared by 62 bps to 28.01% in 2025, then jumped by 60 bps to 11.16% in 2026.
  • Per Business Quant data, the three most recent Return on Capital Employed figures were 11.16% in Q1 2026, 28.01% in Q4 2025, and 34.46% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Lexicon Pharmaceuticals 979.13 Mn 808.47 Mn 20.99 Mn -11.16%

Historic Data

Download Data
DateValue
Mar 31, 2026 -11.16%
Dec 31, 2025 -28.01%
Sep 30, 2025 -34.46%
Jun 30, 2025 -52.19%
Mar 31, 2025 -94.72%
Dec 31, 2024 -74.52%
Sep 30, 2024 -67.84%
Jun 30, 2024 -53.63%
Mar 31, 2024 -62.00%
Dec 31, 2023 -77.57%
Sep 30, 2023 -58.75%
Jun 30, 2023 -60.28%
Mar 31, 2023 -68.63%
Dec 31, 2022 -59.33%
Sep 30, 2022 -71.74%
Jun 30, 2022 -89.10%
Mar 31, 2022 -76.19%
Dec 31, 2021 -65.73%
Sep 30, 2021 -50.25%
Jun 30, 2021 27.01%