Lexicon Pharmaceuticals (LXRX) Operating Income (2010 - 2026)

Lexicon Pharmaceuticals (LXRX) reported Operating Income of -$996000.0 for Q1 2026, up 96.12% year-over-year from -$507848.9 in Q1 2025, and up 93.26% quarter-over-quarter from -$14.8 million in Q4 2025.

Lexicon Pharmaceuticals (LXRX) Operating Income (2010 - 2026) Analysis & Trends

Lexicon Pharmaceuticals (LXRX) has 17 years of Operating Income data on file, last reported at -$996000.0 in Q1 2026.

  • Operating Income for Q1 2026 came in at -$996000.0, up 96.12% year-over-year; the trailing twelve-month figure through Mar 2026 was -$24.2 million (up 86.35% YoY), and the FY2025 annual result was -$48.9 million, up 75.19% from the prior year.
  • Operating Income grew to -$996000.0 in Q1 2026 per LXRX's latest filing, from -$14.8 million in the prior quarter.
  • Over five years, Operating Income peaked at $3.7 million in Q2 2025 and troughed at -$63.7 million in Q3 2024.
  • A 5-year average of -$30.6 million and a median of -$30.3 million in 2022 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2023 and 2025: Operating Income tumbled 114.9% in 2023, then surged 106.75% in 2025.
  • A 5-year view of Operating Income shows it stood at -$30.3 million in 2022, then plunged by 54.36% to -$46.7 million in 2023, then gained by 29.95% to -$32.7 million in 2024, then jumped by 54.85% to -$14.8 million in 2025, then jumped by 93.26% to -$996000.0 in 2026.
  • Business Quant data shows LXRX's Operating Income at -$996000.0 in Q1 2026, -$14.8 million in Q4 2025, and -$12.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Lexicon Pharmaceuticals 804.48 Mn 633.82 Mn 20.99 Mn -996,000.00

Historic Data

Download Data
DateValue
Mar 31, 2026 -996,000.00
Dec 31, 2025 -14.78 Mn
Sep 30, 2025 -12.19 Mn
Jun 30, 2025 3.74 Mn
Mar 31, 2025 -25.68 Mn
Dec 31, 2024 -32.74 Mn
Sep 30, 2024 -63.69 Mn
Jun 30, 2024 -55.35 Mn
Mar 31, 2024 -45.33 Mn
Dec 31, 2023 -46.74 Mn
Sep 30, 2023 -49.63 Mn
Jun 30, 2023 -44.24 Mn
Mar 31, 2023 -31.14 Mn
Dec 31, 2022 -30.28 Mn
Sep 30, 2022 -23.10 Mn
Jun 30, 2022 -24.01 Mn
Mar 31, 2022 -23.38 Mn
Dec 31, 2021 -25.33 Mn
Sep 30, 2021 -22.96 Mn
Jun 30, 2021 -17.96 Mn