Lexicon Pharmaceuticals (LXRX) Net Margin (2010 - 2026)
Lexicon Pharmaceuticals (LXRX) recorded Net Margin of -4591.76% in Q2 2026, down 4603.03 percentage points from 11.27% a year earlier and down 4586.82 percentage points from the prior quarter.
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Analysis
Lexicon Pharmaceuticals (LXRX) Net Margin (2010 - 2026) Analysis & Trends
On a TTM basis, Lexicon Pharmaceuticals' Net Margin came in at -147.38% as of Jun 30, 2026, up 59.05 percentage points year-over-year; for FY2025, it was -101.08%, up 543.70 percentage points from FY2024.
- Annual Net Margin has increased for three straight years, with a five-year change of +143.03 percentage points (FY2020 to FY2025).
- Across earlier years, Net Margin came in at -644.78% in FY2024 (+14066.10 pp), -14710.88% in FY2023 (+58630.13 pp), -73341.01% in FY2022 (-43892.01 pp) and -29448.99% in FY2021 (-29204.88 pp).
- The Q2 2026 figure is the lowest quarterly Net Margin since Q4 2023.
- On a year-over-year basis, Net Margin rose in six of the last eight quarters, with an average year-over-year change of +5104.19 percentage points.
- Peak year-over-year performance for Net Margin in the last five years was a gain of 128775.41 percentage points in Q1 2024, against a drop of 180174.41 percentage points in Q4 2021 at the low end.
- Per Business Quant, the preceding three quarters came in at -4.94% (Q1 2026), -282.72% (Q4 2025) and -90.04% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Lexicon Pharmaceuticals | 849.05 Mn | 275.61 Mn | 653,000.00 | -4,591.76% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -4,591.76% |
| Mar 31, 2026 | -4.94% |
| Dec 31, 2025 | -282.72% |
| Sep 30, 2025 | -90.04% |
| Jun 30, 2025 | 11.27% |
| Mar 31, 2025 | -2,004.36% |
| Dec 31, 2024 | -127.16% |
| Sep 30, 2024 | -3,703.49% |
| Jun 30, 2024 | -3,244.02% |
| Mar 31, 2024 | -4,282.92% |
| Dec 31, 2023 | -7,087.75% |
| Sep 30, 2023 | -31,188.27% |
| Jun 30, 2023 | -14,165.30% |
| Mar 31, 2023 | -133,058.33% |
| Dec 31, 2022 | -108,907.14% |
| Sep 30, 2022 | -59,966.67% |
| Jun 30, 2022 | -70,248.57% |
| Dec 31, 2021 | -182,935.71% |
| Sep 30, 2021 | -100,530.43% |
| Jun 30, 2021 | -7,720.94% |
API Access
Lexicon Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "LXRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();