Lexicon Pharmaceuticals (LXRX) EBITDA Margin (2010 - 2026)
Lexicon Pharmaceuticals (LXRX) reported EBITDA Margin of -3820.52% for Q2 2026, down 3834.07 percentage points from 13.55% a year earlier and down 3816.32 percentage points from the prior quarter.
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Lexicon Pharmaceuticals (LXRX) EBITDA Margin (2010 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Lexicon Pharmaceuticals' EBITDA Margin came in at -130.27%, up 71.28 percentage points year-over-year; for FY2025, it was -96.96%, up 535.52 percentage points from FY2024.
- EBITDA Margin has increased for three consecutive years, with a five-year change of +90.02 percentage points (FY2020 to FY2025).
- By year, EBITDA Margin came in at -632.49% in FY2024 (+13586.45 pp), -14218.94% in FY2023 (+57963.08 pp), -72182.01% in FY2022 (-43055.17 pp) and -29126.85% in FY2021 (-28939.87 pp).
- The Q2 2026 figure ranks as the lowest quarterly EBITDA Margin since Q1 2024.
- Year over year, EBITDA Margin gained in six of the last eight quarters, with an average year-over-year change of +5044.37 percentage points.
- The high point for year-over-year EBITDA Margin in five years was Q1 2024 (a gain of 125292.64 percentage points); the low point was Q4 2021 (a drop of 176553.70 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -4.20% (Q1 2026), -266.92% (Q4 2025) and -84.87% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Lexicon Pharmaceuticals | 849.05 Mn | 275.61 Mn | 653,000.00 | -3,820.52% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3,820.52% |
| Mar 31, 2026 | -4.20% |
| Dec 31, 2025 | -266.92% |
| Sep 30, 2025 | -84.87% |
| Jun 30, 2025 | 13.55% |
| Mar 31, 2025 | -2,020.84% |
| Dec 31, 2024 | -122.81% |
| Sep 30, 2024 | -3,632.40% |
| Jun 30, 2024 | -3,352.46% |
| Mar 31, 2024 | -3,999.03% |
| Dec 31, 2023 | -6,636.75% |
| Sep 30, 2023 | -30,543.21% |
| Jun 30, 2023 | -13,910.41% |
| Mar 31, 2023 | -129,291.67% |
| Dec 31, 2022 | -107,767.86% |
| Sep 30, 2022 | -58,941.03% |
| Jun 30, 2022 | -68,285.71% |
| Dec 31, 2021 | -180,128.57% |
| Sep 30, 2021 | -99,395.65% |
| Jun 30, 2021 | -7,656.84% |
API Access
Lexicon Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "LXRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();