Growth Metrics

Lexicon Pharmaceuticals (LXRX) EBITDA Margin (2010 - 2026)

Lexicon Pharmaceuticals (LXRX) reported EBITDA Margin of 5.7% for Q1 2026, up 200611.0% year-over-year from N/an in Q1 2025, and up 97.98% on a QoQ basis from 282.71% in Q4 2025.

Lexicon Pharmaceuticals (LXRX) has 16 years of EBITDA Margin data on file, last reported at 5.7% in Q1 2026.

  • Quarterly EBITDA Margin rose 200611.0% year-over-year to 5.7% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 37.69% (up 53011.0% YoY) and the FY2025 annual result came in at 101.26%, up 54323.0% from the prior year.
  • EBITDA Margin improved to 5.7% in Q1 2026 per LXRX's latest filing, from 282.71% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 11.13% in Q2 2025 and bottomed at 31196.3% in Q3 2023.
  • The 4-year median for EBITDA Margin is 2632.25% (2024), against an average of 5473.82%.
  • The widest annual swing landed in 2024, when EBITDA Margin soared 2752378 bps; it then sank 15468 bps in 2025.
  • Tracing LXRX's EBITDA Margin over 4 years: stood at 6476.76% in 2023, then surged by 98 bps to 128.03% in 2024, then tumbled by 121 bps to 282.71% in 2025, then surged by 98 bps to 5.7% in 2026.
  • Per Business Quant, the three latest LXRX EBITDA Margin figures stand at 5.7% (Q1 2026), 282.71% (Q4 2025), and 89.73% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 17.24%
10 Lexicon Pharmaceuticals 872.52 Mn 701.87 Mn 20.99 Mn -5.70%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -5.70%
Dec 31, 2025 -282.71%
Sep 30, 2025 -89.73%
Jun 30, 2025 11.13%
Mar 31, 2025 -2,011.81%
Dec 31, 2024 -128.03%
Sep 30, 2024 -3,672.51%
Jun 30, 2024 -3,252.70%
Mar 31, 2024 -4,435.32%
Dec 31, 2023 -6,476.76%
Sep 30, 2023 -31,196.30%
Jun 30, 2023 -14,145.43%
Dec 31, 2021 9,019.72%
Jun 30, 2021 -7,725.21%
Mar 31, 2021 -77,581.48%
Dec 31, 2020 23.30%
Jun 30, 2020 -278,476.00%
Mar 31, 2020 -823.04%
Dec 31, 2019 -585.42%
Sep 30, 2019 76.77%
Jun 30, 2019 -237.19%
Mar 31, 2019 -891.84%
Dec 31, 2018 -97.97%
Sep 30, 2018 -391.17%
Jun 30, 2018 -249.12%
Mar 31, 2018 -165.49%
Dec 31, 2017 -66.18%
Sep 30, 2017 -110.47%
Jun 30, 2017 -289.64%
Mar 31, 2017 -194.63%
Dec 31, 2016 -98.57%
Jun 30, 2016 -189.52%
Mar 31, 2016 -275.07%
Dec 31, 2015 67.94%
Sep 30, 2015 -6,240.64%
Jun 30, 2015 -7,446.54%
Mar 31, 2015 -1,561.94%
Dec 31, 2014 -13.96%
Sep 30, 2014 -9,666.11%
Jun 30, 2014 -3,851.04%
Mar 31, 2014 -11,128.88%
Dec 31, 2013 -1,237.59%
Sep 30, 2013 -13,298.74%
Jun 30, 2013 -13,593.93%
Mar 31, 2013 -7,209.72%
Dec 31, 2012 -11,408.72%
Sep 30, 2012 -7,929.57%
Jun 30, 2012 -13,012.06%
Mar 31, 2012 -9,982.00%
Dec 31, 2011 -9,871.14%
Sep 30, 2011 -7,363.38%
Jun 30, 2011 -4,794.05%
Mar 31, 2011 -4,965.44%
Dec 31, 2010 -1,789.70%
Sep 30, 2010 -3,105.38%
Jun 30, 2010 -1,952.47%