Lexicon Pharmaceuticals (LXRX) EBITDA (2010 - 2026)
Lexicon Pharmaceuticals (LXRX) reported EBITDA of -$1.2 million for Q1 2026, up 95.26% year-over-year from -$616096.2 in Q1 2025, and up 92.25% quarter-over-quarter from -$15.5 million in Q4 2025.
Lexicon Pharmaceuticals (LXRX) EBITDA (2010 - 2026) Analysis & Trends
Lexicon Pharmaceuticals (LXRX) has 17 years of EBITDA data on file, last reported at -$1.2 million in Q1 2026.
- EBITDA for Q1 2026 came in at -$1.2 million, up 95.26% year-over-year; the trailing twelve-month figure through Mar 2026 was -$26.2 million (up 85.19% YoY), and the FY2025 annual result was -$50.4 million, up 74.82% from the prior year.
- EBITDA grew to -$1.2 million in Q1 2026 per LXRX's latest filing, from -$15.5 million in the prior quarter.
- Over five years, EBITDA peaked at $3.2 million in Q2 2025 and troughed at -$64.3 million in Q3 2024.
- A 5-year average of -$31.2 million and a median of -$30.4 million in 2022 frame the typical range for EBITDA.
- The sharpest annual moves came in 2023 and 2025: EBITDA sank 112.99% in 2023, then surged 106.0% in 2025.
- A 5-year view of EBITDA shows it stood at -$30.4 million in 2022, then sank by 63.03% to -$49.6 million in 2023, then jumped by 31.48% to -$34.0 million in 2024, then jumped by 54.32% to -$15.5 million in 2025, then soared by 92.25% to -$1.2 million in 2026.
- Business Quant data shows LXRX's EBITDA at -$1.2 million in Q1 2026, -$15.5 million in Q4 2025, and -$12.7 million in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Lexicon Pharmaceuticals | 804.48 Mn | 633.82 Mn | 20.99 Mn | -1.20 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1.20 Mn |
| Dec 31, 2025 | -15.53 Mn |
| Sep 30, 2025 | -12.73 Mn |
| Jun 30, 2025 | 3.21 Mn |
| Mar 31, 2025 | -25.39 Mn |
| Dec 31, 2024 | -34.00 Mn |
| Sep 30, 2024 | -64.27 Mn |
| Jun 30, 2024 | -53.57 Mn |
| Mar 31, 2024 | -48.48 Mn |
| Dec 31, 2023 | -49.61 Mn |
| Sep 30, 2023 | -50.54 Mn |
| Jun 30, 2023 | -44.84 Mn |
| Mar 31, 2023 | -31.67 Mn |
| Dec 31, 2022 | -30.43 Mn |
| Sep 30, 2022 | -23.73 Mn |
| Jun 30, 2022 | -24.70 Mn |
| Mar 31, 2022 | -23.50 Mn |
| Dec 31, 2021 | -25.62 Mn |
| Sep 30, 2021 | -23.12 Mn |
| Jun 30, 2021 | -18.08 Mn |