Lexicon Pharmaceuticals LXRX
NASDAQ LXRX
$2.23 -0.03 (-1.11%)
As of: Sep 4, 2026 · 2:31 PM EDT

Lexicon Pharmaceuticals (LXRX) EBITDA (2010 - 2026)

Lexicon Pharmaceuticals (LXRX) posted quarterly EBITDA of -$996000.0 for Q1 2026, up 96.12% year-over-year from -$507848.9 in Q1 2025, and up 93.26% quarter-over-quarter from -$14.8 million in Q4 2025.

Analysis

Lexicon Pharmaceuticals (LXRX) EBITDA (2010 - 2026) Analysis & Trends

Lexicon Pharmaceuticals (LXRX) has reported EBITDA for 17 consecutive years, with -$996000.0 the latest figure, recorded in Q1 2026.

  • In Q1 2026, EBITDA rose 96.12% year-over-year to -$996000.0; the TTM figure through Mar 2026 stood at -$24.2 million (up 86.35% YoY), while the FY2025 annual figure was -$48.9 million, up 75.19% from the prior year.
  • EBITDA improved to -$996000.0 in Q1 2026 per LXRX's latest filing, from -$14.8 million in the prior quarter.
  • Across five years, EBITDA topped out at $3.7 million in Q2 2025 and bottomed at -$63.7 million in Q3 2024.
  • Historically, EBITDA has averaged -$30.6 million across 5 years, with a median of -$30.3 million in 2022.
  • Annual changes were most pronounced in 2023 — EBITDA tumbled 114.9% — and 2025, when it surged 106.75%.
  • Lexicon Pharmaceuticals' EBITDA stood at -$30.3 million in 2022, then sank by 54.36% to -$46.7 million in 2023, then advanced by 29.95% to -$32.7 million in 2024, then surged by 54.85% to -$14.8 million in 2025, then surged by 93.26% to -$996000.0 in 2026.
  • Business Quant data shows LXRX's EBITDA at -$996000.0 in Q1 2026, -$14.8 million in Q4 2025, and -$12.2 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 138.78 Bn 130.92 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.50 Bn 77.51 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.51 Bn 58.32 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.06 Bn 52.92 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.04 Bn 44.04 Bn - -505.13 Mn
6 BeOne Medicines 40.04 Bn 34.94 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.45 Bn 32.14 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.41 Bn 27.57 Bn - 133.12 Mn
9 Insmed 27.42 Bn 26.26 Bn 358.27 Mn -1.55 Mn
10 Lexicon Pharmaceuticals 978.15 Mn 787.54 Mn 653,000.00 -26.54 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -26.54 Mn
Mar 31, 2026 -996,000.00
Dec 31, 2025 -14.78 Mn
Sep 30, 2025 -12.19 Mn
Jun 30, 2025 3.74 Mn
Mar 31, 2025 -25.68 Mn
Dec 31, 2024 -32.74 Mn
Sep 30, 2024 -63.69 Mn
Jun 30, 2024 -55.35 Mn
Mar 31, 2024 -45.33 Mn
Dec 31, 2023 -46.74 Mn
Sep 30, 2023 -49.63 Mn
Jun 30, 2023 -44.24 Mn
Mar 31, 2023 -31.14 Mn
Dec 31, 2022 -30.28 Mn
Sep 30, 2022 -23.10 Mn
Jun 30, 2022 -24.01 Mn
Mar 31, 2022 -23.38 Mn
Dec 31, 2021 -25.33 Mn
Sep 30, 2021 -22.96 Mn