Lexicon Pharmaceuticals (LXRX) EBIT Margin (2010 - 2026)
Lexicon Pharmaceuticals' EBIT Margin came in at -3835.26% for Q2 2026, down 3848.20 percentage points from 12.94% a year earlier and down 3830.54 percentage points from the prior quarter.
Powered by 
Analysis
Lexicon Pharmaceuticals (LXRX) EBIT Margin (2010 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Lexicon Pharmaceuticals reported EBIT Margin of -131.43%, up 71.15 percentage points year-over-year; for FY2025, it came in at -98.21%, up 536.00 percentage points from FY2024.
- EBIT Margin has increased in each of the last three years, with a five-year change of +101.00 percentage points (FY2020 to FY2025).
- Going back by year, EBIT Margin was -634.20% in FY2024 (+13630.75 pp), -14264.95% in FY2023 (+58224.26 pp), -72489.21% in FY2022 (-43264.38 pp) and -29224.83% in FY2021 (-29025.62 pp).
- The Q2 2026 figure represents the lowest quarterly EBIT Margin since Q1 2024.
- Year-over-year, EBIT Margin increased in six of the last eight quarters, with an average year-over-year change of +5058.97 percentage points.
- The fastest year-over-year change in EBIT Margin over five years came in Q1 2024 (a gain of 125746.56 percentage points), and the weakest in Q4 2021 (a drop of 177180.83 percentage points).
- Business Quant data shows LXRX's EBIT Margin at -4.72% (Q1 2026), -269.07% (Q4 2025) and -85.93% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Lexicon Pharmaceuticals | 849.05 Mn | 275.61 Mn | 653,000.00 | -3,835.26% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3,835.26% |
| Mar 31, 2026 | -4.72% |
| Dec 31, 2025 | -269.07% |
| Sep 30, 2025 | -85.93% |
| Jun 30, 2025 | 12.94% |
| Mar 31, 2025 | -2,034.79% |
| Dec 31, 2024 | -123.28% |
| Sep 30, 2024 | -3,639.60% |
| Jun 30, 2024 | -3,360.90% |
| Mar 31, 2024 | -4,011.77% |
| Dec 31, 2023 | -6,657.69% |
| Sep 30, 2023 | -30,636.42% |
| Jun 30, 2023 | -13,955.84% |
| Mar 31, 2023 | -129,758.33% |
| Dec 31, 2022 | -108,135.71% |
| Sep 30, 2022 | -59,217.95% |
| Jun 30, 2022 | -68,591.43% |
| Dec 31, 2021 | -180,928.57% |
| Sep 30, 2021 | -99,834.78% |
| Jun 30, 2021 | -7,674.79% |
API Access
Lexicon Pharmaceuticals EBIT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebit-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebit-margin", "ticker": "LXRX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebit-margin&ticker=LXRX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();