Legend Biotech (LEGN) Operating Expenses (2019 - 2025)

Legend Biotech (LEGN) posted Operating Expenses of -$138.3 million for Q4 2025, up 6.47% on a QoQ basis from -$147.9 million in Q3 2025, and little changed year-over-year from -$138.0 million in Q4 2024.

Legend Biotech (LEGN) Operating Expenses (2019 - 2025) Analysis & Trends

Legend Biotech's Operating Expenses history runs 7 years deep, the most recent figure standing at -$138.3 million for Q4 2025.

  • Quarterly Operating Expenses changed 0.22% year-over-year to -$138.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$550.5 million (changed 0.03% YoY) and the FY2025 annual result came in at -$550.5 million, changed 0.04% from the prior year.
  • Operating Expenses was -$138.3 million for Q4 2025 at Legend Biotech, up from -$147.9 million in the prior quarter.
  • Across five years, Operating Expenses topped out at -$79836.0 in Q1 2021 and bottomed at -$172.4 million in Q2 2021.
  • A 5-year average of -$111.6 million and a median of -$125.9 million in 2022 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2022 — Operating Expenses slumped 117898.15% — and 2023, when it soared 99.87%.
  • Legend Biotech's Operating Expenses stood at -$103.6 million in 2021, then retreated by 3.66% to -$107.4 million in 2022, then surged by 99.87% to -$134390.0 in 2023, then sank by 103032.67% to -$138.6 million in 2024, then increased by 0.22% to -$138.3 million in 2025.
  • Business Quant data shows LEGN's Operating Expenses at -$138.3 million in Q4 2025, -$147.9 million in Q3 2025, and -$130.9 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Legend Biotech 8.26 Bn 7.36 Bn - -138.30 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -138.30 Mn
Sep 30, 2025 -147.87 Mn
Jun 30, 2025 -130.90 Mn
Mar 31, 2025 -133.39 Mn
Dec 31, 2024 -138.60 Mn
Sep 30, 2024 -130.82 Mn
Jun 30, 2024 -147.98 Mn
Mar 31, 2024 -132.89 Mn
Dec 31, 2023 -134,390.00
Sep 30, 2023 -123.96 Mn
Jun 30, 2023 -123.54 Mn
Mar 31, 2023 -107.09 Mn
Dec 31, 2022 -107.44 Mn
Sep 30, 2022 -127.76 Mn
Jun 30, 2022 -86.88 Mn
Mar 31, 2022 -94.21 Mn
Dec 31, 2021 -103.65 Mn
Sep 30, 2021 -84.12 Mn
Jun 30, 2021 -172.44 Mn
Mar 31, 2021 -79,836.00