Legend Biotech (LEGN) Operating Expenses (2019 - 2025)
Legend Biotech (LEGN) posted Operating Expenses of -$138.3 million for Q4 2025, up 6.47% on a QoQ basis from -$147.9 million in Q3 2025, and little changed year-over-year from -$138.0 million in Q4 2024.
Legend Biotech (LEGN) has 7 years of Operating Expenses data on file, last reported at -$138.3 million in Q4 2025.
- In Q4 2025, Operating Expenses changed 0.22% year-over-year to -$138.3 million; the TTM figure through Dec 2025 stood at -$550.5 million (changed 0.03% YoY), while the FY2025 annual figure was -$550.5 million, changed 0.04% from the prior year.
- Operating Expenses grew to -$138.3 million in Q4 2025, from -$147.9 million in the prior quarter.
- Across five years, Operating Expenses topped out at -$79836.0 in Q1 2021 and bottomed at -$148.0 million in Q2 2024.
- A 5-year average of -$107.6 million and a median of -$123.8 million in 2023 frame the typical range for Operating Expenses.
- Annual changes were most pronounced in 2022 — Operating Expenses tumbled 117898.15% — and 2023, when it jumped 99.87%.
- Year by year, Operating Expenses stood at -$103.6 million in 2021, then fell by 3.66% to -$107.4 million in 2022, then jumped by 99.87% to -$134390.0 in 2023, then slumped by 103032.67% to -$138.6 million in 2024, then grew by 0.22% to -$138.3 million in 2025.
- The last three Operating Expenses figures came in at -$138.3 million (Q4 2025), -$147.9 million (Q3 2025), and -$130.9 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.97 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 4.33 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -138.30 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 15.76 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.85 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 2.96 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 898.54 Mn |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | 445.22 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -138.30 Mn |
| Sep 30, 2025 | -147.87 Mn |
| Jun 30, 2025 | -130.90 Mn |
| Mar 31, 2025 | -133.39 Mn |
| Dec 31, 2024 | -138.60 Mn |
| Sep 30, 2024 | -130.82 Mn |
| Jun 30, 2024 | -147.98 Mn |
| Mar 31, 2024 | -132.89 Mn |
| Dec 31, 2023 | -134,390.00 |
| Sep 30, 2023 | -123.96 Mn |
| Jun 30, 2023 | -123.54 Mn |
| Mar 31, 2023 | -107.09 Mn |
| Dec 31, 2022 | -107.44 Mn |
| Sep 30, 2022 | -127.76 Mn |
| Jun 30, 2022 | -86.88 Mn |
| Mar 31, 2022 | -94.21 Mn |
| Dec 31, 2021 | -103.65 Mn |
| Sep 30, 2021 | -84.12 Mn |
| Jun 30, 2021 | -92.71 Mn |
| Mar 31, 2021 | -79,836.00 |
| Dec 31, 2020 | -76.11 Mn |
| Sep 30, 2020 | -69.69 Mn |
| Jun 30, 2020 | -58.08 Mn |
| Mar 31, 2020 | -51.43 Mn |
| Dec 31, 2019 | -68.15 Mn |
| Sep 30, 2019 | -43.91 Mn |
| Jun 30, 2019 | -34.25 Mn |