Growth Metrics

Krystal Biotech (KRYS) Gross Margin (2023 - 2025)

Krystal Biotech (KRYS) has disclosed Gross Margin for 3 consecutive years, with 93.84% as the latest value for Q4 2025.

  • Quarterly Gross Margin fell 72.0% to 93.84% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 94.08% through Dec 2025, up 98.0% year-over-year, with the annual reading at 94.08% for FY2025, 98.0% up from the prior year.
  • Gross Margin hit 93.84% in Q4 2025 for Krystal Biotech, down from 95.64% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 97.39% in Q3 2023 to a low of 91.45% in Q2 2024.
  • Historically, Gross Margin has averaged 93.96% across 3 years, with a median of 94.07% in 2025.
  • Biggest five-year swings in Gross Margin: tumbled -537bps in 2024 and later surged 362bps in 2025.
  • Year by year, Gross Margin stood at 93.19% in 2023, then rose by 1bps to 94.57% in 2024, then dropped by -1bps to 93.84% in 2025.
  • Business Quant data shows Gross Margin for KRYS at 93.84% in Q4 2025, 95.64% in Q3 2025, and 92.54% in Q2 2025.