Krystal Biotech (KRYS) Gross Margin (2023 - 2026)
Krystal Biotech (KRYS) reported Gross Margin of 94.57% for Q1 2026, up 27.0% on a YoY basis from 74.46% in Q1 2025, and up 0.77% sequentially from 93.85% in Q4 2025.
Krystal Biotech (KRYS) Gross Margin (2023 - 2026) Analysis & Trends
Krystal Biotech (KRYS) has 4 years of Gross Margin data on file, last reported at 94.57% in Q1 2026.
- For the quarter ending Q1 2026, Gross Margin rose 27.0% year-over-year to 94.57%; the trailing twelve-month figure through Mar 2026 stood at 94.17% (up 97.0% YoY), and the FY2025 full-year result was 94.08%, up 98.0% from the prior year.
- Gross Margin improved to 94.57% in Q1 2026, from 93.85% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 97.39% in Q3 2023 to a low of 91.45% in Q2 2024.
- A 4-year average of 94.02% and a median of 94.3% in 2025 frame the typical range for Gross Margin.
- Across the five-year window, Gross Margin plunged 537 bps in 2024 and surged 361 bps in 2025, its largest moves.
- Tracing KRYS's Gross Margin over 4 years: stood at 93.19% in 2023, then grew by 1 bps to 94.57% in 2024, then retreated by 1 bps to 93.85% in 2025, then climbed by 1 bps to 94.57% in 2026.
- Business Quant data shows KRYS's Gross Margin at 94.57% in Q1 2026, 93.85% in Q4 2025, and 95.64% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | - |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 88.95% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 90.68% |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | - |
| 10 | Krystal Biotech | 9.84 Bn | 9.02 Bn | 110.08 Mn | 94.57% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 94.57% |
| Dec 31, 2025 | 93.85% |
| Sep 30, 2025 | 95.64% |
| Jun 30, 2025 | 92.54% |
| Mar 31, 2025 | 94.30% |
| Dec 31, 2024 | 94.57% |
| Sep 30, 2024 | 92.03% |
| Jun 30, 2024 | 91.45% |
| Mar 31, 2024 | 94.65% |
| Dec 31, 2023 | 93.19% |
| Sep 30, 2023 | 97.39% |