Growth Metrics

Krystal Biotech (KRYS) Gross Margin (2023 - 2025)

Krystal Biotech's Gross Margin history spans 3 years, with the latest figure at 93.84% for Q4 2025.

  • For Q4 2025, Gross Margin fell 72.0% year-over-year to 93.84%; the TTM value through Dec 2025 reached 94.08%, up 98.0%, while the annual FY2025 figure was 94.08%, 98.0% up from the prior year.
  • Gross Margin for Q4 2025 was 93.84% at Krystal Biotech, down from 95.64% in the prior quarter.
  • Across five years, Gross Margin topped out at 97.39% in Q3 2023 and bottomed at 91.45% in Q2 2024.
  • The 3-year median for Gross Margin is 94.07% (2025), against an average of 93.96%.
  • The largest annual shift saw Gross Margin plummeted -537bps in 2024 before it soared 361bps in 2025.
  • A 3-year view of Gross Margin shows it stood at 93.19% in 2023, then increased by 1bps to 94.57% in 2024, then fell by -1bps to 93.84% in 2025.
  • Per Business Quant, the three most recent readings for KRYS's Gross Margin are 93.84% (Q4 2025), 95.64% (Q3 2025), and 92.54% (Q2 2025).