Krystal Biotech (KRYS) Gross Margin (2023 - 2026)
Krystal Biotech's Gross Margin came in at 94.60% for Q2 2026, up 2.06 percentage points from 92.54% a year earlier and up 0.03 percentage points from the prior quarter.
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Analysis
Krystal Biotech (KRYS) Gross Margin (2023 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Krystal Biotech reported Gross Margin of 94.64%, up 1.27 percentage points year-over-year; for FY2025, it was 94.08%, up 0.98 percentage points from FY2024.
- Going back by year, Gross Margin was 93.09% in FY2024 (-0.80 pp) and 93.90% in FY2023.
- The five-year range for quarterly Gross Margin is 91.45% (Q2 2024) to 97.39% (Q3 2023).
- Year-over-year, Gross Margin increased in five of the last eight quarters, with an average year-over-year change of +0.25 percentage points.
- The fastest year-over-year change in Gross Margin over five years came in Q3 2025 (a gain of 3.61 percentage points), and the weakest in Q3 2024 (a drop of 5.37 percentage points).
- Business Quant data shows KRYS's Gross Margin at 94.57% (Q1 2026), 93.85% (Q4 2025) and 95.64% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 68.19% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 74.74% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 73.54% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 78.02% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 83.60% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 72.04% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 79.76% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 72.78% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 85.33% |
| 10 | Krystal Biotech | 9.98 Bn | 6.75 Bn | 112.79 Mn | 94.60% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 94.60% |
| Mar 31, 2026 | 94.57% |
| Dec 31, 2025 | 93.85% |
| Sep 30, 2025 | 95.64% |
| Jun 30, 2025 | 92.54% |
| Mar 31, 2025 | 94.30% |
| Dec 31, 2024 | 94.57% |
| Sep 30, 2024 | 92.03% |
| Jun 30, 2024 | 91.45% |
| Mar 31, 2024 | 94.66% |
| Dec 31, 2023 | 93.19% |
| Sep 30, 2023 | 97.39% |
API Access
Krystal Biotech Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=KRYS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "KRYS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=KRYS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();