Krystal Biotech (KRYS) Gross Margin (2023 - 2026)
Krystal Biotech's (KRYS) quarterly Gross Margin came in at 94.57% in Q1 2026, up 27.0% year-on-year from 74.46% in Q1 2025, and up 0.77% quarter-over-quarter from 93.85% in Q4 2025.
Krystal Biotech (KRYS) Gross Margin (2023 - 2026) Analysis & Trends
Krystal Biotech has disclosed Gross Margin across 4 years of filings, most recently posting 94.57% for Q1 2026.
- Gross Margin for Q1 2026 came in at 94.57%, up 27.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 94.17% (up 96.0% YoY), and the FY2025 annual result was 94.08%, up 98.0% from the prior year.
- Gross Margin came in at 94.57% for Q1 2026 at Krystal Biotech, up from 93.85% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 97.39% in Q3 2023 to a low of 91.45% in Q2 2024.
- The 4-year median for Gross Margin is 94.3% (2025), against an average of 94.02%.
- Across the five-year window, Gross Margin slumped 537 bps in 2024 and surged 361 bps in 2025, its largest moves.
- Krystal Biotech's Gross Margin stood at 93.19% in 2023, then rose by 1 bps to 94.57% in 2024, then declined by 1 bps to 93.85% in 2025, then gained by 1 bps to 94.57% in 2026.
- The last three Gross Margin figures came in at 94.57% (Q1 2026), 93.85% (Q4 2025), and 95.64% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Krystal Biotech | 10.23 Bn | 9.41 Bn | 110.03 Mn | 94.57% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 94.57% |
| Dec 31, 2025 | 93.85% |
| Sep 30, 2025 | 95.64% |
| Jun 30, 2025 | 92.54% |
| Mar 31, 2025 | 94.30% |
| Dec 31, 2024 | 94.57% |
| Sep 30, 2024 | 92.03% |
| Jun 30, 2024 | 91.45% |
| Mar 31, 2024 | 94.66% |
| Dec 31, 2023 | 93.19% |
| Sep 30, 2023 | 97.39% |