Krystal Biotech (KRYS) Gross Margin (2023 - 2026)

Krystal Biotech's (KRYS) quarterly Gross Margin came in at 94.57% in Q1 2026, up 27.0% year-on-year from 74.46% in Q1 2025, and up 0.77% quarter-over-quarter from 93.85% in Q4 2025.

Krystal Biotech (KRYS) Gross Margin (2023 - 2026) Analysis & Trends

Krystal Biotech has disclosed Gross Margin across 4 years of filings, most recently posting 94.57% for Q1 2026.

  • Gross Margin for Q1 2026 came in at 94.57%, up 27.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 94.17% (up 96.0% YoY), and the FY2025 annual result was 94.08%, up 98.0% from the prior year.
  • Gross Margin came in at 94.57% for Q1 2026 at Krystal Biotech, up from 93.85% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 97.39% in Q3 2023 to a low of 91.45% in Q2 2024.
  • The 4-year median for Gross Margin is 94.3% (2025), against an average of 94.02%.
  • Across the five-year window, Gross Margin slumped 537 bps in 2024 and surged 361 bps in 2025, its largest moves.
  • Krystal Biotech's Gross Margin stood at 93.19% in 2023, then rose by 1 bps to 94.57% in 2024, then declined by 1 bps to 93.85% in 2025, then gained by 1 bps to 94.57% in 2026.
  • The last three Gross Margin figures came in at 94.57% (Q1 2026), 93.85% (Q4 2025), and 95.64% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn 94.57%

Historic Data

Download Data
DateValue
Mar 31, 2026 94.57%
Dec 31, 2025 93.85%
Sep 30, 2025 95.64%
Jun 30, 2025 92.54%
Mar 31, 2025 94.30%
Dec 31, 2024 94.57%
Sep 30, 2024 92.03%
Jun 30, 2024 91.45%
Mar 31, 2024 94.66%
Dec 31, 2023 93.19%
Sep 30, 2023 97.39%