Over the past 12 months, Karyopharm Therapeutics insiders sold $349,759 of stock on the open market (38.23K shares) and made no open-market purchases.
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Richard A. Paulson | President And Ceo | 347,378 | 0 | 347,378 | 27.8% | 15 May, 2026 |
| 2 | Sohanya Roshan Cheng | Evp Chief Commercial Officer | 134,175 | 0 | 134,175 | 10.7% | 15 May, 2026 |
| 3 | Stuart Poulton | Evp, Chief Development Officer | 116,601 | 0 | 116,601 | 9.3% | 30 Jul, 2026 |
| 4 | Michael Mano | Evp, Closecretary | 112,922 | 0 | 112,922 | 9.0% | 15 May, 2026 |
| 5 | Michael Kauffman | Chief Executive Officer | 47,586 | 59,878 | 107,465 | 8.6% | 02 Mar, 2022 |
| 6 | Lori Macomber | Evp, Cfo Treasurer | 85,105 | 0 | 85,105 | 6.8% | 04 Feb, 2026 |
| 7 | Reshma Rangwala | Evp Chief Medical Officer | 80,145 | 0 | 80,145 | 6.4% | 15 May, 2026 |
| 8 | Sharon Shacham | Chief Scientific Officer | 63,879 | 0 | 63,879 | 5.1% | 31 Mar, 2022 |
| 9 | Michael Mason | Evp, Cfo Treasurer | 52,657 | 0 | 52,657 | 4.2% | 05 Sep, 2024 |
| 10 | Kristin Abate | Chief Accounting Officer | 23,404 | 0 | 23,404 | 1.9% | 02 Oct, 2026 |
| 11 | Garen G Bohlin | Director | 18,517 | 0 | 18,517 | 1.5% | 26 May, 2026 |
| 12 | Barry E Greene | Director | 16,415 | 0 | 16,415 | 1.3% | 26 May, 2026 |
| 13 | Deepika Pakianathan | Director | 15,508 | 0 | 15,508 | 1.2% | 26 May, 2026 |
| 14 | Chen Schor | Director | 15,508 | 0 | 15,508 | 1.2% | 26 May, 2026 |
| 15 | Zhen Su | Director | 15,508 | 0 | 15,508 | 1.2% | 26 May, 2026 |
| 16 | Christy J. Oliger | Director | 15,508 | 0 | 15,508 | 1.2% | 26 May, 2026 |
| 17 | Ran Frenkel | Evp, Chief Dev. Officer | 11,220 | 0 | 11,220 | 0.9% | 02 Mar, 2022 |
| 18 | Jatin Shah | Evp, Chief Medical Officer | 8,630 | 0 | 8,630 | 0.7% | 22 Feb, 2022 |
| 19 | Stephen Mitchener | Svp, Chief Business Officer | 8,555 | 0 | 8,555 | 0.7% | 02 Mar, 2023 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 01 Oct, 2026 | Kristin Abate | Chief Accounting Officer | Disposed S | 378 | $1.19 | $450 | 23,404 | Direct |
| 01 Sep, 2026 | Kristin Abate | Chief Accounting Officer | Disposed S | 19 | $2.02 | $38 | 23,782 | Direct |
| 28 Jul, 2026 | Stuart Poulton | Evp, Chief Development Officer | Disposed S | 189 | $7.10 | $1.34K | 94,632 | Direct |
| 21 May, 2026 | Deepika Pakianathan | Director | Acquired A | 15,508 | $0.00 | $0 | 15,508 | Direct |
| 21 May, 2026 | Barry E Greene | Director | Acquired A | 15,508 | $0.00 | $0 | 16,415 | Direct |
| 21 May, 2026 | Chen Schor | Director | Acquired A | 15,508 | $0.00 | $0 | 15,508 | Direct |
| 21 May, 2026 | Zhen Su | Director | Acquired A | 15,508 | $0.00 | $0 | 15,508 | Direct |
| 21 May, 2026 | Christy J. Oliger | Director | Acquired A | 15,508 | $0.00 | $0 | 15,508 | Direct |
| 21 May, 2026 | Garen G Bohlin | Director | Acquired A | 15,508 | $0.00 | $0 | 18,517 | Direct |
| 13 May, 2026 | Sohanya Roshan Cheng | Evp Chief Commercial Officer | Acquired A | 947 | $0.00 | $0 | 108,264 | Direct |
| 13 May, 2026 | Michael Mano | Evp, Closecretary | Acquired A | 700 | $0.00 | $0 | 94,664 | Direct |
| 13 May, 2026 | Reshma Rangwala | Evp Chief Medical Officer | Acquired A | 947 | $0.00 | $0 | 57,237 | Direct |
| 13 May, 2026 | Stuart Poulton | Evp, Chief Development Officer | Acquired A | 896 | $0.00 | $0 | 95,224 | Direct |
| 13 May, 2026 | Kristin Abate | Chief Accounting Officer | Acquired A | 121 | $0.00 | $0 | 23,854 | Direct |
| 13 May, 2026 | Richard A. Paulson | President And Ceo | Acquired A | 4,920 | $0.00 | $0 | 271,950 | Direct |
| 14 May, 2026 | Sohanya Roshan Cheng | Evp Chief Commercial Officer | Disposed S | 324 | $9.50 | $3.08K | 107,940 | Direct |
| 14 May, 2026 | Michael Mano | Evp, Closecretary | Disposed S | 266 | $9.50 | $2.53K | 94,398 | Direct |
| 14 May, 2026 | Reshma Rangwala | Evp Chief Medical Officer | Disposed S | 408 | $9.50 | $3.88K | 56,829 | Direct |
| 14 May, 2026 | Stuart Poulton | Evp, Chief Development Officer | Disposed S | 403 | $9.50 | $3.83K | 94,821 | Direct |
| 14 May, 2026 | Richard A. Paulson | President And Ceo | Disposed S | 2,203 | $9.50 | $20.93K | 269,747 | Direct |